J:BMC Biotechnol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT254761 Igh-Dex Positive_regulation of Apoe 1 2 0.00 0.08 0.52
2 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 2 0.02 0.05 0.49
3 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 2 0.00 0 0.42
4 INT297972 MAPK14 Negative_regulation of ING5 1 3 0.21 1.67 0.33
5 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 1 0.00 0.32 0.28
6 INT254769 Binding of LDLR and Apoe 1 4 0.03 0 0.28
7 INT254772 DNMT1 Positive_regulation of Apoe 1 1 0.02 0 0.25
8 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 1 0.01 0.07 0.24
9 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 1 0.01 0.31 0.23
10 INT254770 Regulation of Binding of DNMT1 and Igh-Dex 1 1 0.00 0 0.22
11 INT297965 MAPK14 Negative_regulation of GADD45A 1 2 0.05 1 0.21
12 INT254771 Binding of DNMT1 and Igh-Dex 1 1 0.00 0 0.19
13 INT297967 MAPK14 Negative_regulation of SCUBE3 1 1 0.01 0.67 0.12
14 INT235385 INCENP Negative_regulation of Bche 1 1 0.01 0.19 0.11
15 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 1 0.21 0.26 0.08
16 INT231166 Binding of Aggf1 and Cphx 1 1 0.00 0.2 0.08
17 INT297970 Binding of BMP2 and IL17C 1 1 0.15 0.26 0.08
18 INT297964 Binding of CDK8 and MAP3K11 1 1 0.26 0.29 0.07
19 INT297969 Positive_regulation of Binding of CDK8 and MAP3K11 1 1 0.35 0.29 0.07
20 INT297971 Positive_regulation of Binding of CDK8 and MAPK1 1 1 0.22 0.3 0.07
21 INT297963 Binding of CDK8 and MAPK1 1 1 0.16 0.29 0.07
22 INT298000 MAP3K4 Positive_regulation of Gene_expression of Gadd45b 1 1 0.27 0.72 0.03
23 INT298002 Gene_expression of Gadd45b Positive_regulation of MAPK14 1 1 0.29 0.67 0.03
24 INT298001 Gene_expression of Gadd45b Positive_regulation of MAP3K4 1 1 0.25 0.72 0.03
25 INT297962 MAP3K4 Positive_regulation of MAPK14 1 1 0.21 0.66 0.03
26 INT231167 Cphx Positive_regulation of Gene_expression of Dmd 1 1 0.02 0.17 0
27 INT231168 Binding of Dmd and Nos1 1 1 0.11 0.06 0
28 INT231169 Gnas Positive_regulation of Gene_expression of Dmd 1 1 0.00 0.19 0
29 INT297966 CDKN1A Positive_regulation of TP53 1 1 0.08 0.49 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5972 Gene_expression of IL1B 3 948 0.78 510.91 263.97
2 INT1893 Localization of Gh 1 1041 0.79 340.23 256.58
3 INT120811 Gene_expression of Gopc 1 1174 0.59 428.49 150.55
4 INT812 Localization of INS 1 1026 0.81 515.6 145.31
5 INT60694 Gene_expression of Il10 1 567 0.78 369.48 143.69
6 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 52 1138 0.72 311.58 119.18
7 INT170025 Gene_expression of Fig4 5 588 0.67 183.27 113.32
8 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
9 INT49171 Gene_expression of Nos1 5 241 0.78 140.7 104.76
10 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
11 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
12 INT75999 Gene_expression of BDNF 21 344 0.78 114.19 83.12
13 INT1498 Gene_expression of Gh 1 521 0.75 220.84 81.16
14 INT3034 Localization of Ngf 2 126 0.81 50.81 72.84
15 INT11380 Negative_regulation of IL1B 3 215 0.59 125.62 72.35
16 INT546 Binding of ALB 1 311 0.48 85.98 60.14
17 INT79093 Positive_regulation of Nos1 1 101 0.70 46.89 59.61
18 INT16258 Gene_expression of Ntf3 23 121 0.78 53.93 59.03
19 INT6477 Gene_expression of IL1RN 44 213 0.77 114.69 58.62
20 INT52264 Gene_expression of IK 3 180 0.77 90.87 51.87
21 INT64110 Positive_regulation of Gene_expression of Nos1 2 68 0.70 58.11 51.64
22 INT1232 Positive_regulation of Pdpk1 1 78 0.42 24.33 50.17
23 INT170646 Negative_regulation of Fig4 2 213 0.37 81.29 46.92
24 INT16364 Gene_expression of HLA-DRA 1 234 0.78 118.81 45.01
25 INT5973 Regulation of IL1B 1 109 0.62 66.6 39.88
26 INT101992 Localization of VEGFA 1 413 0.81 258.23 36.15
27 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
28 INT691 Binding of SST 1 67 0.48 24.66 32.67
29 INT28361 Gene_expression of TP53 1 443 0.78 384.86 28.8
30 INT66200 Gene_expression of Gfap 2 215 0.78 88.04 28.25
31 INT83708 Negative_regulation of MAPK1 1 156 0.57 84.93 27.85
32 INT55737 Positive_regulation of MMP2 1 101 0.68 59.11 27.71
33 INT116861 Gene_expression of Apoe 56 182 0.78 100.41 27.26
34 INT86534 Positive_regulation of MAPK14 4 81 0.62 57.81 23.62
35 INT6868 Gene_expression of GFAP 2 136 0.78 84.65 22.7
36 INT171924 Gene_expression of MAPK14 1 60 0.65 54.38 21.68
37 INT101517 Negative_regulation of PPARA 1 168 0.57 112.24 21.41
38 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 5 134 0.61 34.87 20.15
39 INT11803 Positive_regulation of Il2 2 62 0.70 31.44 18.93
40 INT3060 Negative_regulation of Bche 1 94 0.59 46.75 18.51
41 INT103469 Positive_regulation of Gene_expression of BDNF 5 59 0.67 24.39 18.36
42 INT170033 Positive_regulation of Gene_expression of Fig4 1 59 0.43 20.99 16.69
43 INT93361 Gene_expression of Trp53 2 208 0.78 175.35 16.65
44 INT69203 Positive_regulation of Ntf3 4 43 0.66 19.16 16.49
45 INT14887 Gene_expression of Mbp 1 55 0.75 36.13 16.11
46 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 9 95 0.43 24.83 15.69
47 INT170855 Negative_regulation of GOPC 1 188 0.38 70.92 15.41
48 INT170335 Gene_expression of INCENP 19 176 0.54 91.62 15.31
49 INT34590 Gene_expression of ALPP 1 199 0.75 89.85 15.1
50 INT2843 Gene_expression of Epo 2 100 0.78 62.01 14.66
51 INT69952 Positive_regulation of IK 1 45 0.32 16.08 14.59
52 INT88544 Gene_expression of MMRN1 12 102 0.75 68.8 14.55
53 INT26545 Gene_expression of Hras1 5 173 0.78 79.54 13.21
54 INT72565 Localization of IL1RN 15 45 0.80 23.59 13.17
55 INT75224 Positive_regulation of Gene_expression of Ntf3 2 23 0.69 11.79 13.08
56 INT16256 Regulation of Ntf3 1 15 0.49 9.75 13.07
57 INT63361 Gene_expression of CD44 1 126 0.77 71.58 12.96
58 INT174838 Localization of INCENP 5 80 0.64 19.05 12.89
59 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
60 INT158124 Gene_expression of COL5A2 1 136 0.69 72.3 12.44
61 INT48335 Negative_regulation of NOSTRIN 2 38 0.56 16.22 12.05
62 INT16255 Negative_regulation of Ntf3 1 21 0.51 12.92 11.93
63 INT87844 Binding of IL1RN 1 40 0.41 24.37 11.92
64 INT52625 Regulation of IL1RN 1 30 0.61 19.12 11.31
65 INT25963 Gene_expression of DES 1 122 0.75 98.81 11.25
66 INT13240 Gene_expression of TF 1 94 0.76 57.81 10.99
67 INT6474 Positive_regulation of Gene_expression of IL1RN 1 34 0.69 21.87 10.99
68 INT62895 Gene_expression of NOSTRIN 1 51 0.75 28.8 10.68
69 INT72579 Localization of BDNF 4 56 0.80 14.84 10.65
70 INT101474 Positive_regulation of Gene_expression of Gfap 1 61 0.70 38.3 10.35
71 INT17741 Gene_expression of MBP 2 67 0.78 23.67 9.65
72 INT23178 Gene_expression of H1 4 38 0.68 13.37 9.09
73 INT108931 Negative_regulation of BDNF 1 38 0.59 19.61 8.84
74 INT17024 Gene_expression of COL1A2 2 69 0.77 36.38 8.29
75 INT156396 Localization of Tg(CAG-EGFP)D4Nagy 1 61 0.55 13.63 8.17
76 INT81777 Negative_regulation of Gene_expression of IK 2 22 0.08 11.55 8.09
77 INT71381 Localization of Nos1 1 33 0.79 11.46 8.05
78 INT2093 Gene_expression of GAST 1 50 0.78 32.32 7.98
79 INT71689 Localization of Ntf3 1 23 0.73 11.1 7.91
80 INT70814 Negative_regulation of Il2 1 40 0.56 13.36 7.22
81 INT197493 Localization of Apoe 32 61 0.79 27.48 7.06
82 INT76120 Gene_expression of Ptprc 2 102 0.59 30.42 7.02
83 INT132860 Binding of BDNF 1 33 0.47 14.7 6.99
84 INT142264 Positive_regulation of Apoe 11 47 0.50 26.35 6.94
85 INT182351 Positive_regulation of Gene_expression of Apoe 22 38 0.50 19.78 6.72
86 INT8101 Binding of INCENP 1 42 0.31 16.2 6.68
87 INT23246 Gene_expression of HLA-DRB4 1 37 0.64 36.79 6.61
88 INT74865 Gene_expression of Igh-Dex 1 16 0.22 8.95 6.59
89 INT28122 Gene_expression of MSC 3 111 0.58 26.83 6.57
90 INT11258 Gene_expression of Gnas 5 58 0.58 21.6 6.33
91 INT103477 Negative_regulation of Gene_expression of BDNF 2 23 0.52 10.63 6.26
92 INT93359 Positive_regulation of Trp53 1 90 0.70 69.77 6.24
93 INT17551 Positive_regulation of Gene_expression of HLA-DRA 1 31 0.70 15.39 6
94 INT112545 Phosphorylation of TP53 1 28 0.80 14.13 5.93
95 INT63042 Binding of Apoe 8 59 0.48 31.23 5.88
96 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 2 51 0.53 15.32 5.86
97 INT16257 Regulation of Gene_expression of Ntf3 1 8 0.43 4 5.63
98 INT125534 Regulation of Tg(CAG-EGFP)D4Nagy 1 31 0.39 13.88 5.58
99 INT95696 Gene_expression of Dmd 61 130 0.68 26.02 5.34
100 INT134966 Localization of Col7a1 1 23 0.42 16.4 5.24
101 INT19391 Gene_expression of Nt5e 1 44 0.72 13.99 5.14
102 INT23551 Negative_regulation of CNDP2 1 13 0.38 3.05 5.05
103 INT60066 Positive_regulation of NPEPPS 1 17 0.22 11.99 4.83
104 INT94453 Gene_expression of ITGB1 2 50 0.75 18.41 4.72
105 INT92199 Negative_regulation of Gene_expression of IL1RN 3 14 0.58 10.11 4.71
106 INT81485 Negative_regulation of IL1RN 2 19 0.57 8.3 4.69
107 INT26546 Positive_regulation of Gene_expression of Hras1 2 35 0.70 16.59 4.54
108 INT105171 Phosphorylation of RAF1 1 11 0.74 2.33 4.19
109 INT26584 Gene_expression of Nes 1 76 0.75 24.03 4.17
110 INT156097 Negative_regulation of Localization of VEGFA 1 70 0.58 34.96 4.17
111 INT49700 Regulation of Localization of Ngf 1 6 0.59 1.18 3.95
112 INT75996 Transcription of Ntf3 6 13 0.67 4.03 3.88
113 INT94303 Gene_expression of Upf1 1 44 0.04 11.62 3.87
114 INT103350 Gene_expression of DNMT1 1 15 0.67 9.77 3.83
115 INT62784 Gene_expression of NT5E 1 46 0.65 15.95 3.72
116 INT104624 Negative_regulation of Apoe 2 26 0.59 19.25 3.71
117 INT20455 Positive_regulation of Bche 2 15 0.59 7.22 3.7
118 INT71602 Negative_regulation of Trp53 1 84 0.59 67.77 3.68
119 INT191669 Localization of Igh-Dex 1 8 0.26 4.35 3.54
120 INT139807 Gene_expression of Braf 1 7 0.51 8.78 3.34
121 INT95652 Gene_expression of Krt20 6 54 0.61 53.69 3.31
122 INT30192 Regulation of H1 1 10 0.45 4.01 3.3
123 INT172551 Negative_regulation of INCENP 2 38 0.07 20.83 3.14
124 INT76403 Gene_expression of Cnp 1 16 0.70 8.36 3.07
125 INT181804 Negative_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 7 57 0.50 12.54 3
126 INT37715 Positive_regulation of MSC 1 34 0.48 10.52 2.92
127 INT177551 Negative_regulation of Tg(CAG-EGFP)D4Nagy 1 31 0.37 11.16 2.65
128 INT196919 Regulation of Braf 1 3 0.32 6.14 2.55
129 INT174876 Regulation of Gene_expression of Fig4 1 18 0.39 7.83 2.44
130 INT1864 Regulation of Bche 1 18 0.47 6.18 2.44
131 INT57970 Positive_regulation of Rb1 1 17 0.67 7.03 2.36
132 INT114327 Positive_regulation of RAF1 1 26 0.51 20.87 2.32
133 INT206514 Transcription of Tg(CAG-EGFP)D4Nagy 7 19 0.59 3.25 2.32
134 INT208344 Positive_regulation of Localization of Apoe 14 22 0.48 9.6 2.27
135 INT61684 Localization of COL1A2 1 20 0.73 9.31 2.26
136 INT142265 Regulation of Apoe 1 20 0.60 9.52 2.23
137 INT170469 Gene_expression of THY1 1 66 0.65 11.9 2.15
138 INT68865 Gene_expression of ACOX1 1 13 0.52 5.49 2.09
139 INT117197 Gene_expression of Zmat3 15 19 0.05 8.3 2.05
140 INT181107 Gene_expression of Epcam 6 45 0.73 44.33 1.96
141 INT213431 Positive_regulation of Gene_expression of MMRN1 2 15 0.24 9.91 1.96
142 INT48850 Gene_expression of PKN1 7 16 0.52 1.93 1.92
143 INT14503 Binding of BCHE 2 13 0.48 3.95 1.85
144 INT173641 Regulation of MSC 2 13 0.39 2.85 1.82
145 INT181280 Regulation of Gene_expression of INCENP 1 5 0.07 4 1.78
146 INT222031 Localization of Nt5e 2 16 0.75 3.1 1.73
147 INT194242 Positive_regulation of Gene_expression of MBP 1 9 0.45 4.1 1.71
148 INT205269 Positive_regulation of Plec 1 8 0.43 1.78 1.55
149 INT45065 Gene_expression of Ado 1 3 0.54 2.34 1.55
150 INT19181 Gene_expression of Bche 26 35 0.68 16.93 1.52
151 INT222028 Gene_expression of Msc 11 15 0.29 3.65 1.46
152 INT173654 Localization of MAPK14 2 12 0.62 3.16 1.43
153 INT130014 Positive_regulation of BMP2 1 11 0.66 5.34 1.42
154 INT217388 Negative_regulation of Gene_expression of Apoe 5 11 0.59 6.07 1.4
155 INT227424 Binding of Prep 1 6 0.35 2.61 1.39
156 INT171975 Negative_regulation of Gene_expression of INCENP 3 8 0.05 5.24 1.35
157 INT186995 Gene_expression of RBFOX3 2 17 0.30 2.31 1.3
158 INT54587 Positive_regulation of Hras1 1 12 0.27 5.54 1.3
159 INT8476 Binding of Bche 3 10 0.37 4.38 1.29
160 INT123413 Positive_regulation of Tpr 3 7 0.03 1.05 1.25
161 INT31381 Positive_regulation of Gbp1 2 5 0.45 1.82 1.22
162 INT216103 Positive_regulation of Dmd 5 15 0.46 5.92 1.21
163 INT129837 Gene_expression of Nes 1 44 0.75 8.05 1.19
164 INT174156 Localization of Trp53 2 16 0.72 13.52 1.18
165 INT127805 Positive_regulation of Phosphorylation of RAF1 1 3 0.45 1.21 1.17
166 INT23199 Binding of LDLR 2 22 0.47 17.08 1.16
167 INT116436 Negative_regulation of Phosphorylation of TP53 1 2 0.40 0.94 1.16
168 INT45067 Negative_regulation of Ado 1 4 0.34 1.51 1.15
169 INT108559 Gene_expression of Pol 2 46 0.45 30.07 1.14
170 INT231162 Localization of Dmd 1 6 0.71 2.27 1.07
171 INT89847 Positive_regulation of Localization of Nos1 1 10 0.49 2.45 1.01
172 INT174839 Localization of BSG 1 4 0.68 2.91 0.98
173 INT87240 Gene_expression of Aggf1 1 14 0.11 8.41 0.93
174 INT143114 Positive_regulation of Gene_expression of HLA-DRB4 1 5 0.29 5.2 0.92
175 INT183184 Negative_regulation of NUDT6 1 3 0.11 1.32 0.91
176 INT11028 Binding of CNDP2 1 6 0.24 3.47 0.87
177 INT109658 Gene_expression of IL1RAPL1 1 3 0.67 1.8 0.87
178 INT19637 Localization of TF 1 14 0.73 5.74 0.86
179 INT231154 Binding of Aggf1 1 2 0.07 2.18 0.84
180 INT93356 Negative_regulation of Gene_expression of Trp53 2 28 0.53 20.61 0.8
181 INT48851 Positive_regulation of Gene_expression of PKN1 2 2 0.27 0.67 0.78
182 INT197495 Negative_regulation of Localization of Apoe 2 6 0.43 2.19 0.73
183 INT216104 Positive_regulation of Gene_expression of Dmd 13 23 0.46 4.52 0.68
184 INT181282 Transcription of INCENP 1 10 0.11 1.21 0.66
185 INT175580 Localization of APOE 1 10 0.76 18.84 0.65
186 INT108558 Transcription of Pol 1 5 0.35 4.67 0.64
187 INT257455 Binding of PDLIM5 1 2 0.08 1.72 0.64
188 INT88237 Gene_expression of Gbp1 1 9 0.65 5.46 0.61
189 INT200164 Binding of Dmd 1 5 0.42 2.35 0.56
190 INT167649 Positive_regulation of Polr2f 1 2 0.07 0.2 0.55
191 INT105782 Positive_regulation of Krt20 1 9 0.20 9.62 0.53
192 INT209510 Binding of Zmat3 2 1 0.02 0.58 0.53
193 INT197322 Protein_catabolism of Apoe 1 6 0.71 3.52 0.51
194 INT178488 Localization of Aggf1 1 9 0.08 6.18 0.5
195 INT231163 Binding of Peg10 6 7 0.06 3.41 0.5
196 INT98594 Positive_regulation of ILK 1 3 0.70 1.74 0.49
197 INT182357 Gene_expression of Klra8 1 13 0.65 19.55 0.48
198 INT79516 Positive_regulation of Gene_expression of Bche 1 3 0.50 1 0.47
199 INT216108 Negative_regulation of Gene_expression of Dmd 5 12 0.45 1.32 0.46
200 INT231144 Gene_expression of Peg10 3 5 0.27 1.91 0.44
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