J:Bioorg. Med. Chem.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT119917	Zfp821 Positive_regulation of Positive_regulation of Oprd1	1	2	0.01	0	1.82
2	INT119918	Zfp821 Positive_regulation of Binding of ACAA1	1	2	0.00	0	1.64
3	INT143950	Negative_regulation of NFKB1 Positive_regulation of Gene_expression of RELA	1	1	0.45	0.46	0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT58061	Gene_expression of Trpv1	2	1117	0.78	451.54	637.59
2	INT5660	Binding of Oprd1	7	477	0.48	71.86	342.06
3	INT4941	Positive_regulation of Oprd1	2	345	0.70	74.26	304.41
4	INT6406	Binding of Oprm1	2	280	0.48	40.54	226.26
5	INT26472	Regulation of Oprm1	1	191	0.62	35.84	173.1
6	INT6042	Binding of Oprm1	2	248	0.48	31.77	154.34
7	INT5061	Negative_regulation of Mme	1	306	0.59	51.97	136.9
8	INT4658	Binding of OPRM1	2	188	0.48	25.96	136.24
9	INT64201	Negative_regulation of Trpv1	1	203	0.59	79.18	119.75
10	INT8413	Gene_expression of Ptgs1	1	248	0.78	110.17	108.58
11	INT293	Protein_catabolism of Penk	1	161	1.00	11.71	98.45
12	INT6437	Binding of YY1	4	154	0.47	26.3	90.46
13	INT4830	Binding of Trpv1	1	158	0.48	45.11	84.2
14	INT15613	Negative_regulation of Ptgs2	4	160	0.59	71.08	65.08
15	INT73048	Gene_expression of MMP9	2	268	0.77	159.75	57.81
16	INT83602	Positive_regulation of Gene_expression of TRPV1	1	114	0.70	51.19	56.35
17	INT52692	Gene_expression of Ptgs2	1	160	0.78	85.06	55.73
18	INT49436	Binding of TRPV1	3	145	0.48	38.35	55.08
19	INT37219	Gene_expression of TACR1	2	56	0.78	32.4	54.16
20	INT26500	Gene_expression of MMP2	2	201	0.78	110.57	46.9
21	INT4850	Binding of Tac1	1	57	0.47	14.25	42.17
22	INT16194	Binding of CNR1	1	82	0.48	20.75	39.59
23	INT115	Negative_regulation of Maoa	2	65	0.59	16.27	38.66
24	INT6067	Positive_regulation of Positive_regulation of Oprd1	2	37	0.69	6.56	36.58
25	INT11292	Gene_expression of Mme	1	77	0.78	20.98	35.85
26	INT59466	Gene_expression of ISYNA1	2	204	0.77	112.57	35.48
27	INT34465	Regulation of Oprd1	1	34	0.45	7.14	34.29
28	INT9053	Negative_regulation of ALOX5	1	97	0.58	40.34	29.94
29	INT56072	Negative_regulation of NFKB1	2	94	0.59	53.16	28.19
30	INT55737	Positive_regulation of MMP2	1	101	0.68	59.11	27.71
31	INT6382	Regulation of Binding of Oprd1	1	36	0.61	7	26.48
32	INT73047	Positive_regulation of MMP9	1	133	0.68	73.22	26.42
33	INT53015	Gene_expression of TP53INP2	1	50	0.78	9.05	26.23
34	INT55170	Gene_expression of NFKB1	2	97	0.77	52.75	23.04
35	INT34488	Negative_regulation of MMP2	2	85	0.59	41.98	21.72
36	INT4420	Positive_regulation of GOT1	1	103	0.64	88.4	18.38
37	INT8332	Positive_regulation of OPRD1	1	30	0.61	3.88	17.65
38	INT103245	Positive_regulation of Gene_expression of MMP9	1	64	0.68	36.86	15.7
39	INT26501	Positive_regulation of Gene_expression of MMP2	1	51	0.67	39	15.16
40	INT60197	Gene_expression of JUN	1	90	0.78	42.32	14.61
41	INT2396	Regulation of Maoa	1	25	0.62	6.04	13.27
42	INT20715	Binding of Sigmar1	1	45	0.48	4.03	13.17
43	INT57580	Positive_regulation of TACR1	1	18	0.69	9.35	12.47
44	INT93715	Negative_regulation of MMP9	2	69	0.55	36.05	11.73
45	INT20131	Negative_regulation of Mthfs	1	18	0.57	7.93	10.54
46	INT89282	Regulation of MMP9	2	39	0.60	25.45	10.34
47	INT85535	Negative_regulation of Gene_expression of Ptgs2	1	27	0.51	16.04	10.01
48	INT53547	Binding of TACR1	3	22	0.48	5.03	9.48
49	INT26502	Negative_regulation of Gene_expression of MMP2	1	39	0.58	21.45	9.42
50	INT14043	Binding of HP	1	52	0.30	26.56	7.76
51	INT58083	Positive_regulation of DYT10	1	10	0.67	3.66	7.12
52	INT108628	Regulation of MMP2	2	27	0.60	14.85	6.06
53	INT86475	Binding of ACAA1	2	7	0.28	1.83	5.11
54	INT55171	Gene_expression of RELA	2	80	0.75	17.17	4.47
55	INT54776	Binding of Cckbr	1	5	0.42	0	4.45
56	INT2397	Gene_expression of Maoa	1	12	0.77	11.85	3.88
57	INT39691	Positive_regulation of NR1I3	4	2	0.59	1.46	3.88
58	INT67724	Regulation of Gene_expression of ISYNA1	2	14	0.51	5.99	3.62
59	INT17496	Regulation of Maob	1	7	0.60	6.49	3.62
60	INT29356	Positive_regulation of Binding of YY1	1	8	0.67	0.22	3.49
61	INT15757	Gene_expression of JUND	1	11	0.75	2.47	2.86
62	INT130705	Gene_expression of TFAM	1	50	0.77	38.85	2.79
63	INT106468	Regulation of Gene_expression of MMP2	1	11	0.50	3.53	2.77
64	INT143952	Regulation of Gene_expression of MMP9	1	14	0.53	10.16	2.73
65	INT11235	Positive_regulation of IFNA2	1	27	0.69	15.32	2.57
66	INT68781	Negative_regulation of TFAM	1	15	0.58	10.01	2.42
67	INT137960	Positive_regulation of FASLG	1	8	0.67	6.5	2.34
68	INT94181	Gene_expression of VIPR1	1	7	0.58	0.55	1.79
69	INT75503	Regulation of Gene_expression of JUN	1	6	0.21	2.87	1.11
70	INT143956	Regulation of Positive_regulation of MMP9	1	5	0.40	2.61	1.11
71	INT126711	Gene_expression of Bcmo1	1	5	0.60	0.44	1.03
72	INT83253	Positive_regulation of Git1	6	7	0.41	1.4	0.87
73	INT127452	Positive_regulation of CDK5	1	5	0.32	1.88	0.87
74	INT83251	Negative_regulation of Git1	6	7	0.59	1.4	0.81
75	INT65846	Negative_regulation of Pltct1	1	2	0.53	0.23	0.78
76	INT143953	Regulation of Positive_regulation of MMP2	1	3	0.44	2.25	0.69
77	INT39730	Gene_expression of PFDN4	1	4	0.75	2.4	0.59
78	INT144092	Localization of Nono	1	1	0.29	0.5	0.57
79	INT127451	Positive_regulation of Cdk1	1	1	0.20	0.27	0.4
80	INT9344	Regulation of Atp9a	1	6	0.28	1.74	0.37
81	INT83252	Negative_regulation of Negative_regulation of Git1	4	3	0.43	1	0.35
82	INT84000	Positive_regulation of Negative_regulation of Git1	2	3	0.40	0.61	0.34
83	INT84001	Negative_regulation of Positive_regulation of Git1	4	1	0.36	1.22	0.34
84	INT136550	Binding of FOXI2	1	1	0.01	0.37	0.3
85	INT67725	Positive_regulation of Binding of TACR1	1	1	0.04	0.09	0.28
86	INT143954	Regulation of Gene_expression of JUND	1	1	0.20	0.48	0.23
87	INT143955	Negative_regulation of Negative_regulation of NFKB1	1	1	0.35	0.48	0.2
88	INT108952	Regulation of DPYS	1	1	0.08	0	0.1
89	INT108953	Binding of DPYS	1	1	0.05	0.09	0.08