View source for J:Clin Investig


This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.



==Single Events==

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

{| class="wikitable sortable"
|-
! style="color: black; border: 1px solid lightgray;"| Int No
! style="color: black; border: 1px solid lightgray;"| Page link
! style="color: black; border: 1px solid lightgray;" align="center"| Event String
! style="color: black; border: 1px solid lightgray;" align="center"| Reported in Journal
! style="color: black; border: 1px solid lightgray;" align="center"| Documents
! style="color: black; border: 1px solid lightgray;"| TM Confidence
! style="color: black; border: 1px solid lightgray;" align="center"| Disease Relevance
! style="color: black; border: 1px solid lightgray;" align="center"| Pain Relevance
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT796]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''Penk'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1902
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.78
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 275.47
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 1057.59
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT797]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#800000">'''Penk'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 812
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 111.13
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 542.24
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 3
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT5597]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''Pdyn'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 433
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.78
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 62.97
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 235.47
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 4
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT2651]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''Pomc'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 403
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.70
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 95.72
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 206.24
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 5
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT2391]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''PTGS1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 501
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.59
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 207.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 205.6
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT1652]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#800000">'''Pomc'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 387
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 61.01
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 186.51
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 7
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT5116]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''IL2'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 670
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.78
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 291.13
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 146.69
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT2780]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''Penk'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 265
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 32.45
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 143.88
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 9
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT5595]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''Pdyn'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 223
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.70
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 48.37
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 130.14
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 10
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT1878]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''HLA-B'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 440
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.48
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 321.16
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 127.36
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 11
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT4207]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#800000">'''Avp'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 267
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 63.72
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 115.33
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 12
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT5594]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#800000">'''Pdyn'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 137
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 27.04
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 86.63
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 13
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT749]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''HLA-B'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 341
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.75
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 224.12
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 77.37
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 14
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT5593]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''Pdyn'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 114
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.70
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 29.1
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 74.46
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 15
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT15913]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''CYP2D6'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 174
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.59
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 22.45
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 70.91
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 16
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT3375]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''IGHE'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 535
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.77
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 387.47
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 65.46
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 17
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT7565]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Transcription'''</span> of <span style="color:#800000">'''Pomc'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 69
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.72
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 14.46
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 27.41
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 18
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT3466]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''Ptger1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 39
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.75
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 18.34
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 15.75
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 19
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT1734]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''HSD11B1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 116
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 125.13
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 10.52
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 20
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT47860]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''Cyp1a2'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 20
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 6.06
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 10
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 21
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT1925]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''PLAT'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 47
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.75
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 34.76
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 7.88
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 22
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT11823]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''GGT1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 53
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.67
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 45.84
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 7.55
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 23
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT11826]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''LDLR'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.62
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 45.09
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 6.21
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 24
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT10806]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Transcription'''</span> of <span style="color:#800000">'''Pomc'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 13
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.50
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 1.74
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 4.58
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 25
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT32557]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''PTGS1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 8
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.43
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 3.44
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 2.1
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 26
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT10807]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Regulation'''</span> of <span style="color:#800000">'''Chrna3'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.31
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.84
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 27
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT11824]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''GGT1'''</span>
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 3
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 1.39
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.53
|-
|}