J:Clin Ther

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.


Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT50058 Negative_regulation of Cpox 8 907 0.58 426.28 428.29
2 INT6580 Negative_regulation of Ptgs1 10 929 0.59 381.53 376.26
3 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
4 INT49750 Negative_regulation of CPOX 2 735 0.58 360.06 274.19
5 INT6406 Binding of Oprm1 1 280 0.48 40.54 226.26
6 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
7 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
8 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
9 INT4936 Localization of Tacr1 1 125 0.80 35.7 107.7
10 INT4860 Positive_regulation of CALCA 1 148 0.00 73.35 97.61
11 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
12 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
13 INT5759 Positive_regulation of Ptgs1 2 127 0.69 53.45 53.04
14 INT52611 Negative_regulation of Ptgs2 1 142 0.59 66.31 52.71
15 INT2604 Positive_regulation of Got1 2 223 0.70 154.78 49.51
16 INT7093 Negative_regulation of CYP2B6 1 146 0.58 37.3 48.39
17 INT3252 Negative_regulation of INS 2 428 0.59 271.65 39.52
18 INT11650 Negative_regulation of Gpt 1 122 0.59 69.15 30.36
19 INT19396 Regulation of Rac1 1 66 0.53 37.41 30.01
20 INT16814 Negative_regulation of COX5A 1 74 0.57 33.72 28.63
21 INT59449 Negative_regulation of Timp1 1 76 0.42 54.86 26.99
22 INT49850 Negative_regulation of PDE4A 3 105 0.58 76.91 26.59
23 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
24 INT72370 Gene_expression of Timp1 1 82 0.65 57.52 24.16
25 INT8640 Positive_regulation of HSD11B1 1 332 0.67 377.84 22.36
26 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
27 INT45840 Positive_regulation of Gene_expression of Ptgs1 1 35 0.50 16.07 20.49
28 INT76336 Negative_regulation of PDE5A 4 192 0.59 112.02 20.09
29 INT7581 Binding of ADHD1 1 132 0.46 135.1 19.73
30 INT13510 Gene_expression of ERBB2 3 530 0.78 405.68 16.79
31 INT67855 Negative_regulation of PPIG 2 64 0.57 17.83 13.54
32 INT3602 Negative_regulation of Shbg 1 148 0.53 69.05 11.65
33 INT1735 Gene_expression of HSD11B1 1 199 0.75 257.87 11.5
34 INT37390 Regulation of Crp 1 39 0.46 28.74 11.45
35 INT27687 Regulation of Cp 1 20 0.53 9.75 10.8
36 INT10982 Negative_regulation of Agtr1a 1 42 0.58 22.42 10.29
37 INT25834 Positive_regulation of Dbp 2 59 0.68 24.34 9.32
38 INT33220 Negative_regulation of ras 1 110 0.58 70.21 9.19
39 INT23264 Negative_regulation of Positive_regulation of Ptgs1 1 16 0.39 8.47 8.9
40 INT5458 Negative_regulation of Tbxa2r 1 31 0.54 10.58 8.89
41 INT22798 Regulation of Shbg 1 64 0.60 26.71 8.76
42 INT8637 Negative_regulation of Dbp 3 112 0.50 33.28 8.4
43 INT197 Gene_expression of Hrh2 2 24 0.63 12.35 8.37
44 INT21685 Gene_expression of ras 1 115 0.66 85.6 7.76
45 INT17686 Negative_regulation of Hdl1 1 72 0.36 81.85 7.74
46 INT11957 Negative_regulation of LPA 2 52 0.59 39.09 6.84
47 INT52180 Binding of Aes 1 38 0.42 23.16 6.7
48 INT15376 Positive_regulation of Gene_expression of ERBB2 3 215 0.70 168.54 5.23
49 INT57638 Positive_regulation of M1 1 7 0.40 6.08 5.03
50 INT7346 Localization of Hrh2 1 15 0.69 5.78 4.79
51 INT2836 Positive_regulation of PAEP 1 51 0.67 26.69 4.57
52 INT29231 Regulation of Dbp 4 44 0.53 10.08 4.47
53 INT146355 Negative_regulation of Aes 1 15 0.51 7.83 4.25
54 INT3405 Gene_expression of BCAR1 1 14 0.71 8.89 4.02
55 INT37380 Negative_regulation of Sis 1 31 0.55 19.89 3.92
56 INT17819 Regulation of Agtr2 1 10 0.51 9.33 3.9
57 INT9748 Negative_regulation of Sysbp1 3 28 0.35 8.93 3.87
58 INT17685 Negative_regulation of Cog1 1 23 0.42 15.65 3.56
59 INT10057 Gene_expression of Ldlr 1 35 0.67 23.99 3.05
60 INT24610 Positive_regulation of CCHCR1 1 9 0.70 1.71 2.59
61 INT81388 Localization of Xpr1 1 6 0.55 2.26 2.09
62 INT35431 Regulation of DFP 1 3 0.25 1.33 1.97
63 INT16205 Localization of ras 1 25 0.73 18.99 1.85
64 INT140175 Regulation of Kit 1 23 0.62 8.59 1.79
65 INT41314 Gene_expression of GGTLC1 1 9 0.59 5.61 1.79
66 INT38207 Positive_regulation of Tes 1 7 0.40 3.47 1.7
67 INT30532 Negative_regulation of DFP 1 4 0.43 0.9 1.7
68 INT52962 Binding of ERBB2 1 77 0.47 50.03 1.49
69 INT83822 Protein_catabolism of CYP2C9 1 3 0.46 1.16 1.31
70 INT79598 Regulation of PDE5A 2 16 0.60 8.68 1.17
71 INT84377 Positive_regulation of Acp1 1 2 0.31 1.11 1.08
72 INT155156 Gene_expression of TCN1 2 13 0.58 3.25 0.99
73 INT94514 Localization of COX5A 1 3 0.78 0.54 0.9
74 INT11949 Negative_regulation of Apob 1 11 0.09 8.13 0.85
75 INT142025 Localization of Bid 1 13 0.69 8.24 0.84
76 INT1869 Negative_regulation of SLC17A5 2 12 0.42 5.51 0.75
77 INT100063 Regulation of CCHCR1 1 4 0.50 0.07 0.74
78 INT84376 Negative_regulation of Acp1 1 1 0.26 0.75 0.71
79 INT57637 Localization of M1 1 6 0.24 2.3 0.69
80 INT69486 Negative_regulation of Bcl2a1c 1 34 0.10 19.03 0.6
81 INT60241 Negative_regulation of HMGCL 1 2 0.06 0.33 0.6
82 INT54407 Regulation of Gene_expression of Hrh2 1 2 0.41 1.63 0.54
83 INT103942 Binding of BPHL 1 11 0.30 14.26 0.53
84 INT140515 Positive_regulation of TSPAN33 1 2 0.44 0.63 0.51
85 INT79597 Positive_regulation of Negative_regulation of PDE5A 1 5 0.50 3.39 0.41
86 INT79599 Protein_catabolism of PDE5A 1 7 1.00 3.16 0.39
87 INT160210 Negative_regulation of Gene_expression of ras 1 7 0.36 3.96 0.27
88 INT34907 Gene_expression of Trdn 1 1 0.07 0.08 0.19
89 INT69485 Regulation of Bcl2a1c 2 14 0.34 9.99 0.13
90 INT72493 Gene_expression of Cd164 2 1 0.15 0 0
91 INT72491 Regulation of Cd164 1 1 0.07 0 0
92 INT90182 Regulation of Igkv2-95-2 1 1 0.00 0 0
93 INT72492 Positive_regulation of Gene_expression of Cd164 1 1 0.12 0 0
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