J:Diabetes

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT30423 Penk Regulation of Localization of Ins1 4 2 0.26 0.77 4.42
2 INT30424 Penk Regulation of Localization of Sst 1 3 0.20 0 3.1
3 INT75283 SST Negative_regulation of Localization of INS 2 1 0.47 1.45 0.96
4 INT30422 Penk Regulation of Ins1 1 1 0.06 0 0.85
5 INT30425 Penk Regulation of Sst 1 1 0.20 0 0.84
6 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 1 0.03 0 0.81
7 INT133854 Mcc Positive_regulation of Ngf 1 1 0.00 0.9 0.56
8 INT40728 SST Regulation of IRG1 1 1 0.11 0.36 0.38
9 INT141760 Nfkb1 Regulation of CADM1 1 1 0.02 1.18 0.16
10 INT141761 Nfkb1 Regulation of Positive_regulation of CADM1 1 1 0.01 1.21 0.16
11 INT141759 Nfkb1 Regulation of PECAM1 1 1 0.01 1.18 0.16
12 INT141753 Nfkb1 Regulation of Ptgs2 1 1 0.16 1.18 0.16
13 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 1 0.16 1.21 0.16
14 INT141762 Nfkb1 Regulation of Positive_regulation of PECAM1 1 1 0.01 1.21 0.16
15 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 1 0.17 0.07 0.14
16 INT31224 POMC Regulation of PPY 2 1 0.03 0 0.1
17 INT31225 POMC Regulation of Gene_expression of PPY 2 1 0.04 0 0.1
18 INT32621 POMC Positive_regulation of Positive_regulation of GCG 1 1 0.35 0.05 0.06
19 INT32622 POMC Negative_regulation of Negative_regulation of GCG 1 1 0.30 0.05 0.05
20 INT112644 INS Negative_regulation of OVGP1 1 1 0.43 0 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT292 Localization of Penk 6 876 0.81 88.44 669.14
2 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
3 INT6580 Negative_regulation of Ptgs1 5 929 0.59 381.53 376.26
4 INT720 Positive_regulation of POMC 3 807 0.70 237.37 353.83
5 INT49750 Negative_regulation of CPOX 2 735 0.58 360.06 274.19
6 INT1005 Localization of Sst 10 385 0.81 26.31 244.56
7 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
8 INT2651 Positive_regulation of Pomc 6 403 0.70 95.72 206.24
9 INT50670 Gene_expression of CPOX 2 763 0.76 442.13 195.02
10 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
11 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
12 INT5513 Negative_regulation of Pomc 6 295 0.59 60.9 158.63
13 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
14 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
15 INT65054 Positive_regulation of Nfkb1 1 285 0.70 149.33 126.73
16 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
17 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
18 INT90 Localization of Gast 8 400 0.81 137.67 113
19 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
20 INT74058 Gene_expression of Nos1 1 260 0.78 80.04 95.71
21 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
22 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
23 INT5610 Positive_regulation of Insr 4 140 0.69 37.26 86.24
24 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
25 INT4631 Positive_regulation of Sst 1 127 0.70 17.37 83.29
26 INT2155 Negative_regulation of Sst 2 111 0.59 16.58 77.74
27 INT7534 Gene_expression of Ifng 2 193 0.78 111.02 68.6
28 INT8388 Positive_regulation of Vip 1 142 0.70 39.72 67.61
29 INT7280 Positive_regulation of Localization of Sst 2 97 0.70 5.64 63.37
30 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
31 INT12175 Positive_regulation of PDYN 1 86 0.69 18.27 62.04
32 INT1437 Negative_regulation of Pomc 1 132 0.59 35.22 60.97
33 INT6623 Gene_expression of NA 1 231 0.78 45.78 59.36
34 INT1307 Positive_regulation of Localization of Pomc 2 120 0.70 24.58 58.48
35 INT1200 Negative_regulation of Ins1 4 274 0.58 155.17 56.14
36 INT69876 Negative_regulation of Nfkb1 1 147 0.58 89.81 55.5
37 INT5034 Negative_regulation of Insr 9 100 0.55 28.08 54.5
38 INT1486 Negative_regulation of Cpe 2 85 0.59 28.78 54.08
39 INT22546 Positive_regulation of Gene_expression of Casp3 1 97 0.70 47.89 51.92
40 INT5118 Regulation of SST 2 97 0.62 34.35 51.74
41 INT5957 Positive_regulation of Cpe 1 65 0.69 21.07 51.22
42 INT5098 Negative_regulation of Localization of Sst 3 70 0.58 3.56 51.17
43 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
44 INT17915 Gene_expression of Insr 5 141 0.75 47.45 48.59
45 INT531 Gene_expression of GH1 3 376 0.75 193.45 46.24
46 INT2275 Negative_regulation of Localization of Ins1 8 183 0.59 51.02 44.94
47 INT27493 Negative_regulation of Casp3 1 114 0.56 56.89 44.63
48 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
49 INT8465 Regulation of Ptgs1 2 100 0.57 36.03 44.41
50 INT5214 Localization of Cpe 1 49 0.73 13.3 44.36
51 INT2782 Regulation of Gene_expression of Pomc 1 75 0.62 15.04 38.97
52 INT64558 Negative_regulation of Nos1 1 88 0.58 26.76 36.78
53 INT65055 Negative_regulation of Nfkb1 2 83 0.58 44.85 34.94
54 INT79060 Gene_expression of NOS2 2 116 0.78 69.25 34.84
55 INT7282 Regulation of Localization of Sst 2 58 0.62 1.92 34.83
56 INT48924 Positive_regulation of Mapk3 3 107 0.67 50.53 34.05
57 INT11325 Gene_expression of HLA-E 1 209 0.76 98.05 33.72
58 INT65536 Negative_regulation of Positive_regulation of Nfkb1 1 77 0.59 38.86 33.33
59 INT985 Negative_regulation of GH1 1 213 0.57 89.53 32.39
60 INT5418 Negative_regulation of Alox5 1 108 0.57 42.09 31.17
61 INT2278 Regulation of Localization of Gast 5 81 0.62 16.93 30.64
62 INT1179 Negative_regulation of Ace 1 157 0.59 67.03 30.46
63 INT1473 Localization of Gcg 3 95 0.80 17.35 30.31
64 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
65 INT91 Positive_regulation of Localization of Gast 4 96 0.70 23.22 29.36
66 INT5300 Regulation of Insr 1 54 0.60 11.33 29.26
67 INT55908 Gene_expression of Ngfr 3 74 0.78 34.46 28.8
68 INT62710 Gene_expression of HGF 5 160 0.78 88.27 26.14
69 INT100423 Gene_expression of Bax 1 141 0.75 98.43 24.48
70 INT79061 Positive_regulation of NOS2 4 92 0.65 58.89 23.96
71 INT250 Regulation of GHRH 2 65 0.61 17.46 23.19
72 INT71875 Localization of Nfkb1 6 92 0.78 48.13 22.94
73 INT21503 Binding of Ptgs1 1 45 0.48 15.6 22.29
74 INT3593 Gene_expression of ADRA1D 1 70 0.75 29.48 20.87
75 INT955 Gene_expression of GHRH 2 126 0.78 59.91 20.74
76 INT7017 Regulation of Npr1 1 45 0.52 3.38 20.05
77 INT65907 Negative_regulation of Gene_expression of Ngf 3 36 0.59 19.5 20.03
78 INT35086 Positive_regulation of Gene_expression of Ifng 2 40 0.69 22.55 18.35
79 INT9900 Positive_regulation of Vwf 1 80 0.69 51.85 18.13
80 INT107454 Positive_regulation of Stat3 3 43 0.68 19.63 17.69
81 INT64046 Negative_regulation of DYT10 1 20 0.57 7.86 16.15
82 INT6110 Negative_regulation of Gene_expression of Ins1 1 83 0.56 60.59 16.07
83 INT6381 Negative_regulation of Chat 1 51 0.59 19.68 15.86
84 INT79458 Localization of Prkca 1 30 0.81 11.13 15.78
85 INT74449 Positive_regulation of B4GALNT1 2 53 0.30 34.49 14.96
86 INT105387 Gene_expression of HIF1A 2 116 0.77 98.62 14.66
87 INT17035 Positive_regulation of TFPI 2 55 0.61 34.88 14.18
88 INT49089 Gene_expression of Rab38 1 22 0.45 6.79 13.76
89 INT78480 Localization of Nfkb1 4 39 0.80 23.14 13.64
90 INT71879 Negative_regulation of Localization of Nfkb1 4 30 0.57 21.8 13.48
91 INT15921 Positive_regulation of Serpine1 2 85 0.68 81.24 13.4
92 INT6575 Positive_regulation of Localization of Gcg 2 33 0.69 3.48 13.31
93 INT28952 Negative_regulation of Gene_expression of IGF1 1 75 0.58 41.11 12.32
94 INT90673 Gene_expression of LOX 2 66 0.65 69.71 12.18
95 INT5515 Negative_regulation of Positive_regulation of Pomc 6 25 0.58 8.73 11.88
96 INT787 Localization of Ptgs1 3 31 0.80 12.36 11.55
97 INT95369 Positive_regulation of Gene_expression of NOS2 2 36 0.55 25.09 11.37
98 INT1108 Gene_expression of PPY 1 58 0.75 36.57 10.76
99 INT17349 Negative_regulation of Akr1b1 2 41 0.59 27.03 10.65
100 INT90114 Regulation of Gene_expression of Nos1 1 18 0.62 6.38 10.52
101 INT952 Negative_regulation of GHRH 1 57 0.56 25.3 10.34
102 INT48131 Gene_expression of Slc2a4 2 32 0.78 14.64 10.16
103 INT99505 Gene_expression of Bcl2l1 1 42 0.77 33.12 10.15
104 INT65058 Binding of Nfkb1 1 36 0.45 19.87 10.02
105 INT102110 Positive_regulation of Gene_expression of Bax 1 42 0.67 35.77 9.51
106 INT62997 Gene_expression of Kcnj6 1 17 0.77 2.16 9.44
107 INT111133 Negative_regulation of Mapk3 1 31 0.57 10.89 8.9
108 INT90674 Negative_regulation of LOX 1 56 0.57 38.01 8.58
109 INT3658 Regulation of Gcg 1 28 0.53 12.89 8.58
110 INT28671 Positive_regulation of Gene_expression of HLA-E 1 43 0.67 22.85 8.39
111 INT18021 Positive_regulation of Binding of Oprm1 1 16 0.70 2.53 8.38
112 INT75921 Negative_regulation of Ngfr 2 13 0.59 8.58 8.35
113 INT12762 Negative_regulation of Positive_regulation of Ins1 1 24 0.59 8.51 8.28
114 INT99430 Positive_regulation of Gene_expression of Slc2a4 2 18 0.66 10.45 7.79
115 INT126583 Positive_regulation of PARP1 1 50 0.68 41.44 7.78
116 INT116552 Positive_regulation of Localization of Nfkb1 2 16 0.61 12.7 7.74
117 INT31226 Localization of PPY 1 20 0.78 9.93 6.8
118 INT74944 Positive_regulation of Gene_expression of HGF 5 31 0.70 17.69 6.68
119 INT3041 Positive_regulation of MIA3 2 34 0.56 21.11 6.49
120 INT11826 Positive_regulation of LDLR 1 62 0.62 45.09 6.21
121 INT25193 Negative_regulation of Pck1 1 20 0.57 5.66 6.05
122 INT25822 Negative_regulation of Positive_regulation of Cpe 1 7 0.29 2.43 6.02
123 INT141751 Localization of Syt1 2 21 0.78 11.19 5.98
124 INT86799 Gene_expression of Pck1 1 20 0.65 6.22 5.8
125 INT3894 Negative_regulation of Localization of Gcg 2 18 0.52 2.7 5.77
126 INT94428 Negative_regulation of Gene_expression of NOS2 1 20 0.47 11.61 5.62
127 INT6276 Negative_regulation of Positive_regulation of Pomc 1 12 0.57 3.65 5.49
128 INT9325 Gene_expression of Igf1r 1 14 0.77 8.74 5.48
129 INT92398 Negative_regulation of Localization of Nfkb1 2 17 0.42 11.24 5.4
130 INT141750 Positive_regulation of Localization of Syt1 2 10 0.67 5.53 5.28
131 INT87211 Positive_regulation of Localization of Nfkb1 4 27 0.59 15.84 5.25
132 INT18681 Gene_expression of Thy1 1 80 0.71 38.8 5.23
133 INT6577 Regulation of Alox5 2 18 0.47 9.19 5.06
134 INT22022 Regulation of PPY 1 8 0.26 5.52 5.02
135 INT64160 Negative_regulation of Gene_expression of Prkca 1 8 0.43 3.01 4.72
136 INT82354 Positive_regulation of PECAM1 1 25 0.34 22.93 4.69
137 INT116614 Positive_regulation of Gene_expression of Bcl2l1 1 12 0.67 11.39 4.68
138 INT24620 Negative_regulation of Gene_expression of Insr 4 14 0.39 6.98 4.61
139 INT141000 Negative_regulation of GSK 3 24 0.57 9.46 4.4
140 INT8744 Regulation of Localization of Gcg 3 14 0.60 2.06 4.3
141 INT94427 Positive_regulation of Positive_regulation of NOS2 1 14 0.47 11.15 4.3
142 INT4360 Gene_expression of Hypism 1 29 0.22 38.1 4.07
143 INT17548 Negative_regulation of Serpine1 1 30 0.57 24.69 3.93
144 INT9677 Negative_regulation of Gene_expression of GH1 1 46 0.48 23.32 3.68
145 INT8748 Positive_regulation of Localization of Gcg 1 24 0.67 9.74 3.46
146 INT14060 Negative_regulation of Negative_regulation of Insr 2 6 0.53 3.53 3.44
147 INT61540 Negative_regulation of Gene_expression of Ngfr 3 11 0.59 6.36 3.43
148 INT74946 Negative_regulation of Gene_expression of HGF 2 14 0.58 6.29 3.39
149 INT99348 Negative_regulation of PARP1 2 38 0.58 30.96 3.36
150 INT52694 Negative_regulation of Positive_regulation of Ptgs2 1 9 0.43 4.72 3.11
151 INT76403 Gene_expression of Cnp 1 16 0.70 8.36 3.07
152 INT95778 Gene_expression of Prkcb 1 5 0.75 2.3 2.97
153 INT89133 Transcription of NOS2 1 13 0.71 6.84 2.93
154 INT2256 Regulation of Gip 1 14 0.47 4.69 2.91
155 INT32623 Negative_regulation of Regulation of INS 1 16 0.43 10.96 2.9
156 INT65053 Positive_regulation of Binding of Nfkb1 1 11 0.65 3.78 2.84
157 INT8652 Protein_catabolism of Ace 1 10 0.94 4.7 2.74
158 INT18585 Regulation of Ugt1a10 2 4 0.03 0.54 2.69
159 INT141752 Negative_regulation of Localization of Syt1 2 5 0.42 4.96 2.68
160 INT115250 Positive_regulation of Slc2a4 1 16 0.67 8.13 2.64
161 INT39414 Gene_expression of SNRPB 3 37 0.59 14.07 2.52
162 INT130633 Negative_regulation of Gene_expression of Pck1 1 6 0.37 3.19 2.48
163 INT126581 Positive_regulation of Gli3 1 6 0.35 1.59 2.48
164 INT140993 Negative_regulation of Positive_regulation of Stat3 1 6 0.38 3.39 2.39
165 INT68087 Regulation of Vwf 1 9 0.39 8.06 2.36
166 INT39413 Negative_regulation of SNRPB 1 7 0.31 2.57 2.36
167 INT53476 Positive_regulation of Localization of Ptgs1 3 6 0.49 2.88 2.35
168 INT3182 Negative_regulation of PPY 1 12 0.42 4.65 2.28
169 INT24621 Regulation of Gene_expression of Insr 1 9 0.42 2.68 2.18
170 INT95781 Positive_regulation of Gene_expression of Prkcb 1 3 0.07 1.86 2.17
171 INT15983 Regulation of Gcg 1 6 0.58 1.67 2.16
172 INT6635 Negative_regulation of Cnp 1 9 0.57 5.85 2.15
173 INT89130 Positive_regulation of Transcription of NOS2 1 7 0.50 3.32 2.14
174 INT140991 Negative_regulation of Stat3 1 15 0.53 7.55 2.04
175 INT93009 Regulation of HBN1 1 24 0.17 17.6 2.03
176 INT55106 Positive_regulation of Sub1 1 8 0.20 3.81 1.93
177 INT9336 Negative_regulation of Gene_expression of Igf1r 1 4 0.42 3.53 1.92
178 INT101010 Positive_regulation of Positive_regulation of B4GALNT1 1 5 0.06 4.49 1.83
179 INT98580 Positive_regulation of CADM1 1 11 0.49 10.16 1.78
180 INT80195 Regulation of Gene_expression of Rab38 1 2 0.04 2.23 1.66
181 INT13951 Regulation of Nil 1 4 0.10 2.96 1.6
182 INT140247 Negative_regulation of Negative_regulation of Ngfr 2 3 0.33 3.15 1.59
183 INT98773 Negative_regulation of Localization of Gcg 4 10 0.53 9.59 1.5
184 INT104941 Negative_regulation of Prkcb 1 4 0.39 2.94 1.47
185 INT140245 Binding of Gli3 1 3 0.36 2.65 1.46
186 INT18587 Localization of Ugt1a10 1 2 0.05 0.17 1.45
187 INT61753 Binding of HBN1 1 13 0.09 21.66 1.38
188 INT98020 Gene_expression of PCK1 1 4 0.53 1.21 1.37
189 INT95939 Positive_regulation of GSK 2 19 0.67 10 1.33
190 INT140992 Positive_regulation of Pak2 2 1 0.27 1.15 1.31
191 INT99532 Positive_regulation of PCK1 1 2 0.25 1.19 1.25
192 INT48129 Negative_regulation of Slc2a4 1 7 0.59 3.19 1.21
193 INT45553 Negative_regulation of PCK1 1 3 0.43 0.73 1.17
194 INT99530 Negative_regulation of Gene_expression of PCK1 1 1 0.05 0.54 1.17
195 INT99533 Negative_regulation of Positive_regulation of PCK1 1 1 0.05 0.54 1.17
196 INT99531 Positive_regulation of Gene_expression of PCK1 1 1 0.05 0.54 1.16
197 INT18586 Negative_regulation of Regulation of Ins1 1 8 0.43 2.89 1.15
198 INT23834 Negative_regulation of AKR1B1 1 8 0.55 3.79 1.15
199 INT135289 Negative_regulation of Akr1b3 3 4 0.58 5.35 1.15
200 INT25432 Negative_regulation of Gene_expression of GHRH 1 6 0.37 2.9 1.12
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