J:Diagn Pathol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT316546 Binding of GH1 and SST 2 1 0.03 0.55 0.54
2 INT305547 VEGFA Positive_regulation of Gtf3a 2 1 0.00 1.83 0.48
3 INT263917 Binding of SST and Sstr5 2 1 0.02 0.56 0.45
4 INT354195 Binding of GH1 and Sstr5 1 1 0.00 0.1 0.17
5 INT354114 Binding of CALR and SST 1 1 0.01 0.1 0.16
6 INT311666 Binding of BCL2 and TP53 1 1 0.19 1.26 0.14
7 INT354194 Mtpn Negative_regulation of MIR524 1 1 0.00 0.08 0.11
8 INT354120 Binding of IGF2 and IGFBP5 1 1 0.01 0.45 0.09
9 INT354124 Binding of IGF2 and IGFBP3 1 1 0.01 0.45 0.09
10 INT321597 Binding of MUC1 and MIB1 1 1 0.19 0.98 0.08
11 INT354113 Binding of IGFBP3 and MIR524 1 1 0.01 0.69 0.07
12 INT354125 Binding of IGFBP3 and MIR15B 1 1 0.00 0.7 0.07
13 INT214437 NCAM1 Regulation of CHGA 1 1 0.05 1.21 0.07
14 INT354126 Binding of IGFALS and MIR125A 1 1 0.23 0.7 0.07
15 INT354111 Binding of IGFBP3 and MIR125A 1 1 0.11 0.7 0.07
16 INT354109 Binding of IGFALS and MIR15B 1 1 0.00 0.7 0.07
17 INT354116 Binding of IGFALS and MIR524 1 1 0.02 0.69 0.07
18 INT213903 Binding of EGFR and ERBB2 10 1 0.37 5.03 0.04
19 INT204246 ETFA Regulation of CD68 1 1 0.37 1.05 0.04
20 INT204247 S100B Regulation of CD68 1 1 0.03 1.05 0.04
21 INT354123 MIR124-1 Negative_regulation of Gene_expression of CTDSP1 1 1 0.01 0.15 0
22 INT305038 CD99 Regulation of DES 1 1 0.12 1.25 0
23 INT305542 Binding of Rb1 and Trp53 1 1 0.00 0.9 0
24 INT354122 MIR126 Regulation of PIK3CG 1 3 0.03 2.01 0
25 INT353872 Binding of KCNH1 and KCNH2 1 1 0.25 0.98 0
26 INT192956 Binding of CD2 and KIT 1 1 0.03 0.62 0
27 INT321642 Binding of Cd3e and Spn 1 2 0.00 1.08 0
28 INT354112 MIR126 Regulation of Localization of MIR381 1 1 0.01 0.7 0
29 INT305540 Binding of Trp53 and Tpt1 1 1 0.07 0.9 0
30 INT192955 Binding of KIT and VCAM1 1 1 0.05 0.63 0
31 INT353870 Binding of KCNH1 and KCNH2 Negative_regulation of KCNH1 1 1 0.28 0.98 0
32 INT354115 MIR222 Regulation of Gene_expression of CDKN1B 1 1 0.07 0.98 0
33 INT354127 MIR381 Regulation of GH1 1 1 0.00 0.69 0
34 INT307586 Binding of EGFR and CDCP1 1 1 0.01 0.51 0
35 INT305541 Binding of Bcl2 and Trp53 1 1 0.05 0.9 0
36 INT305539 Binding of Mki67 and Trp53 1 1 0.20 0.91 0
37 INT353871 Negative_regulation of Binding of KCNH1 and KCNH2 1 1 0.30 0.98 0
38 INT354119 MIR381 Regulation of Localization of MIR126 1 1 0.01 0.7 0
39 INT354110 MIR126 Regulation of GH1 1 1 0.01 0.69 0
40 INT307585 Binding of EGFR and MET 1 1 0.11 0.52 0
41 INT305543 Binding of Top2a and Trp53 1 1 0.37 0.91 0
42 INT252851 Binding of GFAP and Ema 1 1 0.05 1.98 0
43 INT307584 Binding of EGFR and IGF1R 1 1 0.03 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT1912 Gene_expression of Calca 7 1152 0.78 453.25 739.84
2 INT443 Localization of POMC 5 1020 0.81 284.52 443.17
3 INT467 Gene_expression of POMC 16 1048 0.78 332.8 394.16
4 INT720 Positive_regulation of POMC 2 807 0.70 237.37 353.83
5 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
6 INT68684 Gene_expression of VEGFA 10 2371 0.78 1742.52 259.2
7 INT1562 Localization of Crh 4 499 0.81 126.74 236.68
8 INT438 Gene_expression of Crh 16 376 0.78 159.11 169.17
9 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
10 INT5497 Positive_regulation of Crh 1 299 0.70 125.54 131.14
11 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
12 INT252 Localization of GH1 27 529 0.80 227.4 122.05
13 INT6128 Positive_regulation of Localization of POMC 2 256 0.70 68.77 121.64
14 INT17612 Gene_expression of CRP 1 676 0.78 580.61 119.03
15 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
16 INT90091 Gene_expression of GOPC 6 967 0.67 366.22 103.6
17 INT5780 Regulation of Gene_expression of Calca 1 90 0.62 59.52 85.03
18 INT68682 Positive_regulation of VEGFA 2 640 0.70 454.14 81.65
19 INT39565 Gene_expression of Ptger2 2 424 0.75 229.28 72.68
20 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
21 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
22 INT8347 Gene_expression of SST 1 181 0.78 104.59 65.45
23 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
24 INT73048 Gene_expression of MMP9 3 268 0.77 159.75 57.81
25 INT82650 Gene_expression of Bcl2 7 312 0.78 211.71 55.03
26 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
27 INT19775 Localization of Il1 1 183 0.78 145.5 50.91
28 INT53083 Gene_expression of Ptgs2 1 153 0.78 90.04 50.39
29 INT531 Gene_expression of GH1 6 376 0.75 193.45 46.24
30 INT20492 Gene_expression of MMP12 6 89 0.76 81.36 46.12
31 INT16364 Gene_expression of HLA-DRA 2 234 0.78 118.81 45.01
32 INT13556 Gene_expression of CD4 2 367 0.78 230.82 41.74
33 INT3987 Positive_regulation of IGHE 1 316 0.70 283.2 40.16
34 INT1931 Positive_regulation of Gene_expression of POMC 5 116 0.70 37.26 38.67
35 INT77307 Gene_expression of Bcl2 1 399 0.77 319.77 38
36 INT101992 Localization of VEGFA 3 413 0.81 258.23 36.15
37 INT255 Regulation of Localization of GH1 2 89 0.62 18.71 35.3
38 INT1624 Gene_expression of Cea 2 212 0.76 180.44 34.21
39 INT10248 Gene_expression of KRT20 3 436 0.78 231.96 32.88
40 INT691 Binding of SST 2 67 0.48 24.66 32.67
41 INT985 Negative_regulation of GH1 2 213 0.57 89.53 32.39
42 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
43 INT65960 Gene_expression of BCL2 15 352 0.78 312.03 30.73
44 INT7412 Positive_regulation of SST 4 71 0.70 24.44 29.48
45 INT28361 Gene_expression of TP53 9 443 0.78 384.86 28.8
46 INT1196 Positive_regulation of Positive_regulation of POMC 1 51 0.70 15.99 28.58
47 INT6174 Regulation of Gene_expression of POMC 1 49 0.61 9.75 27.69
48 INT100861 Binding of CRP 1 179 0.48 175.2 26.45
49 INT17739 Gene_expression of S100B 6 226 0.78 132.7 26.4
50 INT19856 Gene_expression of CD8A 1 240 0.75 147.86 26.39
51 INT9682 Positive_regulation of IGF1 1 238 0.70 120.03 26.36
52 INT20462 Binding of ESR1 1 210 0.44 102.7 26.34
53 INT15777 Gene_expression of Pvalb 1 66 0.78 25.97 26.13
54 INT130176 Positive_regulation of Gene_expression of CRP 1 125 0.66 137.06 25.9
55 INT11159 Gene_expression of EGFR 24 698 0.78 548.93 25.69
56 INT9886 Gene_expression of Ptgs1 1 92 0.77 40.66 25.31
57 INT4877 Gene_expression of MME 1 184 0.78 122.82 24.78
58 INT64185 Gene_expression of TNFRSF11A 1 131 0.76 75.15 24.73
59 INT27933 Gene_expression of NCOR2 1 65 0.72 31.35 24.23
60 INT22708 Gene_expression of MUC1 1 297 0.78 232.71 24.19
61 INT6868 Gene_expression of GFAP 6 136 0.78 84.65 22.7
62 INT91891 Gene_expression of Kit 1 268 0.78 158.89 22.67
63 INT823 Negative_regulation of ESR1 1 144 0.58 63.72 22.52
64 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
65 INT16303 Negative_regulation of Localization of GH1 2 89 0.59 37.31 22.15
66 INT69993 Positive_regulation of Gene_expression of Cpox 1 93 0.55 69.4 22.05
67 INT11161 Gene_expression of HLA-DRB1 4 121 0.78 75.33 20.96
68 INT440 Regulation of Gene_expression of Crh 2 44 0.62 17.71 20.73
69 INT28215 Gene_expression of CDKN1A 2 196 0.76 113.9 18.3
70 INT9900 Positive_regulation of Vwf 2 80 0.69 51.85 18.13
71 INT23635 Positive_regulation of MMP12 1 31 0.59 28.19 17.95
72 INT2120 Gene_expression of CD79A 1 159 0.78 111.69 17.16
73 INT49379 Localization of MMP12 1 26 0.77 13.07 16.93
74 INT13510 Gene_expression of ERBB2 10 530 0.78 405.68 16.79
75 INT93361 Gene_expression of Trp53 30 208 0.78 175.35 16.65
76 INT5841 Gene_expression of Vim 14 181 0.72 138.54 16.33
77 INT10214 Gene_expression of VIM 6 153 0.78 115.88 16.29
78 INT103245 Positive_regulation of Gene_expression of MMP9 1 64 0.68 36.86 15.7
79 INT9783 Gene_expression of INSRR 12 81 0.50 32.99 15.52
80 INT171666 Regulation of GOPC 1 117 0.39 40.41 15.47
81 INT93482 Localization of Rela 2 56 0.78 24.52 14.82
82 INT75502 Positive_regulation of CDKN1A 1 123 0.68 70.75 14.74
83 INT20611 Gene_expression of Asap1 1 55 0.65 23.71 14.62
84 INT52696 Positive_regulation of Ptgs2 1 48 0.70 27.65 14.44
85 INT53080 Positive_regulation of Ptgs1 1 42 0.42 23.58 14.37
86 INT16321 Gene_expression of Cd3e 1 111 0.72 49.9 14.21
87 INT37722 Gene_expression of NCAM1 2 103 0.75 81.57 14.18
88 INT190204 Positive_regulation of Gene_expression of MMP12 1 22 0.67 31.31 13.69
89 INT78472 Gene_expression of CDKN2A 1 223 0.78 173.76 13.61
90 INT12464 Binding of MET 1 38 0.47 10.3 13.15
91 INT46619 Gene_expression of CSF1 4 80 0.73 36.63 12.94
92 INT24876 Gene_expression of CD34 2 172 0.78 91.02 12.39
93 INT8224 Gene_expression of CHGA 2 73 0.75 53.63 12.31
94 INT36287 Binding of CD4 1 96 0.47 58.93 11.88
95 INT111476 Gene_expression of TP63 1 88 0.76 61.08 11.64
96 INT69029 Gene_expression of PTPRC 1 127 0.75 74.26 11.57
97 INT82684 Positive_regulation of Pecam1 1 27 0.49 25.67 11.47
98 INT25963 Gene_expression of DES 4 122 0.75 98.81 11.25
99 INT93129 Negative_regulation of KCNH2 2 42 0.54 9.63 10.85
100 INT6515 Gene_expression of BGLAP 1 110 0.75 45.13 10.81
101 INT15054 Gene_expression of Mme 2 48 0.77 42.52 10.63
102 INT27651 Gene_expression of S100A12 2 45 0.76 52.25 10.51
103 INT94454 Gene_expression of CD68 6 73 0.72 63.94 10.43
104 INT49129 Positive_regulation of GFAP 1 35 0.69 28.78 10.38
105 INT130867 Gene_expression of TNFSF11 2 106 0.77 45.15 10.34
106 INT10019 Binding of CD8A 1 57 0.36 31.49 10.08
107 INT53590 Gene_expression of PRF1 1 33 0.58 23.46 10.02
108 INT33099 Negative_regulation of INSRR 1 32 0.40 13.82 9.85
109 INT2036 Localization of EGF 2 42 0.77 21.5 9.74
110 INT24328 Gene_expression of Egf 2 97 0.75 59.65 9.42
111 INT64346 Positive_regulation of S100B 2 95 0.70 63.11 9.17
112 INT9899 Gene_expression of Vwf 2 91 0.74 45.06 9.13
113 INT64849 Gene_expression of Ret 1 24 0.75 14.36 9.1
114 INT9548 Gene_expression of CHKB 1 99 0.65 50.86 9.03
115 INT82685 Gene_expression of Pecam1 1 36 0.76 27.95 9.01
116 INT49325 Gene_expression of Cd34 8 102 0.78 82.75 8.97
117 INT69264 Gene_expression of KIT 34 207 0.78 179.41 8.95
118 INT80420 Gene_expression of IFI27 2 145 0.78 63.61 8.83
119 INT70017 Positive_regulation of BCL2 1 87 0.67 66.62 8.68
120 INT4991 Positive_regulation of Vim 2 74 0.69 69.84 8.33
121 INT65959 Positive_regulation of Gene_expression of BCL2 1 75 0.70 77.3 8.27
122 INT36798 Gene_expression of Mki67 9 178 0.77 132 8.24
123 INT6557 Gene_expression of Eno2 1 65 0.77 54.42 8.17
124 INT276358 Gene_expression of MIR150 1 42 0.74 38.44 7.82
125 INT84894 Gene_expression of Calb2 3 45 0.73 24.65 7.81
126 INT111607 Gene_expression of CDH1 3 103 0.75 90.45 7.77
127 INT8669 Positive_regulation of Afp 1 66 0.70 58.21 7.67
128 INT74520 Positive_regulation of CD68 3 30 0.61 31.68 7.59
129 INT153300 Negative_regulation of Gene_expression of CRP 1 48 0.58 39.97 7.58
130 INT24891 Gene_expression of SYP 2 55 0.75 45.76 7.53
131 INT91527 Gene_expression of CTSK 3 38 0.78 22.21 7.42
132 INT103154 Gene_expression of FLT1 3 138 0.76 58.5 7.41
133 INT91445 Regulation of Bcl2 1 50 0.56 38.8 7.41
134 INT5381 Gene_expression of FYN 1 18 0.75 7.65 7.35
135 INT102572 Gene_expression of Ccnd1 1 79 0.69 56.37 7.34
136 INT26462 Gene_expression of DNAH8 1 44 0.78 19.36 7.31
137 INT97055 Positive_regulation of Gene_expression of Trp53 1 51 0.70 45.7 7.25
138 INT83531 Gene_expression of KITLG 6 54 0.65 26 7.07
139 INT17049 Localization of CD4 1 57 0.75 35.33 6.89
140 INT25609 Localization of Il1f5 1 17 0.80 10.66 6.71
141 INT84685 Regulation of BCL2 2 67 0.60 72.96 6.65
142 INT6512 Gene_expression of PTH 1 103 0.77 76.29 6.33
143 INT11154 Binding of EGFR 1 149 0.48 96.23 6.29
144 INT93359 Positive_regulation of Trp53 1 90 0.70 69.77 6.24
145 INT86600 Gene_expression of KCNH2 12 37 0.78 14.88 6.14
146 INT92916 Gene_expression of Acta2 3 50 0.74 17.52 6.11
147 INT79425 Gene_expression of SMN1 4 42 0.65 36.37 6.1
148 INT9683 Binding of GH1 1 57 0.47 21.14 5.99
149 INT87470 Gene_expression of SDC1 2 27 0.78 24.86 5.81
150 INT100422 Negative_regulation of Gene_expression of Bcl2 1 46 0.58 28.86 5.7
151 INT38671 Positive_regulation of KRT20 2 62 0.53 40.17 5.6
152 INT87420 Gene_expression of BCL2L1 1 56 0.75 48.84 5.32
153 INT15376 Positive_regulation of Gene_expression of ERBB2 5 215 0.70 168.54 5.23
154 INT70613 Negative_regulation of Gene_expression of BCL2 1 48 0.59 38.91 5.22
155 INT60585 Regulation of TP53 1 59 0.59 54.55 5.21
156 INT3165 Gene_expression of LYZ 2 25 0.65 16.72 5.16
157 INT28084 Positive_regulation of VIM 3 49 0.67 35.12 5.15
158 INT99549 Gene_expression of CDKN1B 1 30 0.75 17 5.15
159 INT10889 Gene_expression of F8 1 60 0.78 41.36 5.06
160 INT11158 Positive_regulation of Gene_expression of EGFR 12 165 0.70 131.26 4.93
161 INT105393 Positive_regulation of Localization of VEGFA 1 66 0.70 45.45 4.9
162 INT18898 Positive_regulation of CHGA 1 38 0.67 28.99 4.86
163 INT56032 Positive_regulation of NCAM1 3 38 0.49 26.01 4.68
164 INT62684 Negative_regulation of TP53 2 66 0.58 66.09 4.62
165 INT68216 Binding of NF1 3 40 0.48 51.24 4.59
166 INT54911 Localization of FOS 1 20 0.78 3.27 4.56
167 INT57749 Negative_regulation of Gene_expression of TP53 2 39 0.56 36.79 4.45
168 INT5870 Negative_regulation of IFNA2 1 20 0.49 12 4.3
169 INT63113 Positive_regulation of HRAS 1 30 0.67 22.85 4.28
170 INT20372 Localization of Il5 2 26 0.41 18.33 4.27
171 INT48518 Gene_expression of ANPEP 1 51 0.78 22.88 4.18
172 INT93016 Binding of TNFRSF11A 1 29 0.47 19.67 4.17
173 INT4988 Gene_expression of KRT1 2 64 0.77 43.4 4.12
174 INT111477 Gene_expression of KRT7 9 90 0.74 86.76 4.07
175 INT75688 Binding of KITLG 5 24 0.30 11.73 4.06
176 INT23317 Gene_expression of Spn 1 20 0.48 14.51 4.01
177 INT80421 Positive_regulation of IFI27 1 26 0.65 15.32 3.93
178 INT68269 Gene_expression of CD99 5 49 0.77 47.38 3.86
179 INT84809 Positive_regulation of Gene_expression of MUC1 1 39 0.70 36.42 3.75
180 INT93399 Gene_expression of Ccnd1 6 38 0.58 21 3.65
181 INT149332 Gene_expression of CD163 2 19 0.75 13.63 3.65
182 INT46621 Positive_regulation of Gene_expression of CSF1 1 17 0.47 10.53 3.59
183 INT19491 Gene_expression of CD19 2 44 0.75 28.8 3.47
184 INT78284 Positive_regulation of PTPRC 2 40 0.49 27.17 3.45
185 INT101068 Negative_regulation of CDCP1 1 27 0.03 17.67 3.45
186 INT5286 Gene_expression of ANTXR2 1 46 0.75 21.06 3.41
187 INT109403 Regulation of Gene_expression of BCL2 2 31 0.60 31.22 3.4
188 INT79270 Gene_expression of MKI67 2 113 0.77 63.52 3.38
189 INT57252 Negative_regulation of PGR 2 22 0.43 12.95 3.33
190 INT95652 Gene_expression of Krt20 1 54 0.61 53.69 3.31
191 INT51607 Positive_regulation of DES 1 33 0.67 32.24 3.29
192 INT67379 Positive_regulation of Cd34 3 38 0.58 26.18 3.28
193 INT36286 Binding of Cd3e 1 33 0.36 10.11 3.21
194 INT190189 Positive_regulation of Localization of MMP12 1 4 0.58 2.87 3.18
195 INT91890 Positive_regulation of Kit 1 36 0.50 25.44 3.06
196 INT11775 Gene_expression of Ema 5 39 0.65 38.12 2.99
197 INT130865 Positive_regulation of TNFSF11 2 29 0.69 12.82 2.99
198 INT48219 Gene_expression of SLC4A1 7 34 0.75 33.18 2.84
199 INT144264 Gene_expression of KCNH1 23 6 0.65 17.69 2.83
200 INT8095 Gene_expression of ERBB3 10 47 0.77 24.85 2.82
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