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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT169768 Binding of Slc6a4 and Mir16-1 1 2 0.33 0 1.25
2 INT169769 Mir16-1 Regulation of Slc6a4 1 1 0.24 0 0.74
3 INT136682 Binding of BRAF and MC1R 2 1 0.49 3.16 0.57
4 INT168200 Binding of CA1 and Nav1 1 1 0.11 0 0.39
5 INT132382 Nos2 Positive_regulation of PTGS2 1 1 0.02 0.1 0.23
6 INT102380 Ptgs1 Negative_regulation of Binding of Tbxa2r 1 1 0.04 0.16 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT18357 Gene_expression of TRPV1 1 825 0.78 307.11 382.81
2 INT16260 Gene_expression of Bdnf 1 671 0.78 283.44 339.1
3 INT9381 Positive_regulation of TRPV1 1 523 0.70 187.4 276.05
4 INT94450 Gene_expression of Nav1 1 359 0.78 131.85 275.46
5 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
6 INT48953 Positive_regulation of Nos2 3 486 0.70 239.85 131.87
7 INT16253 Positive_regulation of Gene_expression of Bdnf 1 196 0.70 92.67 113.01
8 INT69764 Positive_regulation of Cnr1 2 126 0.70 67.8 91.49
9 INT74376 Gene_expression of Cnr1 1 173 0.78 73.43 89.7
10 INT21737 Binding of MC1R 1 129 0.48 45.45 56.54
11 INT31186 Negative_regulation of Insrr 1 81 0.37 24.91 55.94
12 INT49436 Binding of TRPV1 1 145 0.48 38.35 55.08
13 INT37219 Gene_expression of TACR1 3 56 0.78 32.4 54.16
14 INT62426 Gene_expression of Mc1r 1 127 0.78 42.99 48.01
15 INT111051 Negative_regulation of Nav1 1 64 0.59 25.51 47.27
16 INT50308 Binding of Cnr1 1 61 0.48 14.41 33.52
17 INT67620 Negative_regulation of Gene_expression of Bdnf 1 53 0.59 22.45 28.5
18 INT91775 Gene_expression of Slc6a4 5 102 0.78 26.45 28.23
19 INT74726 Negative_regulation of Slc6a4 1 61 0.59 21.01 27.84
20 INT111081 Gene_expression of CA1 1 19 0.75 51.09 26.64
21 INT11625 Localization of App 1 98 0.78 55.46 20.86
22 INT79955 Localization of Cnr1 1 26 0.81 8.44 19.06
23 INT100096 Regulation of Slc6a4 1 24 0.62 7.25 12.28
24 INT17619 Regulation of COMT 1 12 0.45 8.46 12.22
25 INT64451 Negative_regulation of MC1R 1 21 0.59 4.94 9.22
26 INT85651 Positive_regulation of ACACA 1 17 0.67 4.73 8.63
27 INT34009 Binding of Tbxa2r 1 33 0.36 17.98 8.01
28 INT60148 Regulation of Sigmar1 1 20 0.43 7.23 7.76
29 INT20348 Negative_regulation of Tbxa2r 1 47 0.59 19.88 7.68
30 INT99262 Gene_expression of Defb42 1 16 0.31 9.99 7.38
31 INT112873 Gene_expression of Glyr1 1 28 0.76 2.88 5.94
32 INT55917 Binding of Sigmar1 2 26 0.45 12.65 5.58
33 INT133638 Gene_expression of Dbh 3 9 0.78 1.23 5.46
34 INT140142 Positive_regulation of Sigmar1 1 17 0.63 3.78 5.26
35 INT122675 Negative_regulation of Gene_expression of Slc6a4 3 14 0.59 6.4 4.69
36 INT99263 Localization of Defb42 1 7 0.16 4.03 4.46
37 INT139533 Binding of Il23r 2 17 0.47 7.67 4.14
38 INT102850 Gene_expression of Trpv3 1 12 0.56 2.06 4.01
39 INT112872 Negative_regulation of Glyr1 2 9 0.42 2.4 3.59
40 INT126223 Binding of Nos2 3 17 0.37 6 3.22
41 INT99261 Negative_regulation of Localization of Defb42 1 5 0.11 2.71 2.83
42 INT99260 Negative_regulation of Defb42 2 6 0.11 2.98 2.79
43 INT102379 Negative_regulation of Ptgir 1 7 0.51 4.23 2.68
44 INT169765 Gene_expression of Mir16-1 2 6 0.63 3.21 2.47
45 INT120726 Positive_regulation of Gene_expression of Slc6a4 1 4 0.68 0.51 2.34
46 INT105760 Negative_regulation of Casr 1 5 0.58 0.93 2.17
47 INT133637 Negative_regulation of Gene_expression of Dbh 1 2 0.43 0.25 1.46
48 INT169762 Regulation of Mir16-1 2 1 0.22 0 1.25
49 INT74464 Binding of GNPTAB 2 9 0.17 3.32 1.17
50 INT169759 Localization of S100a1 1 5 0.43 0.78 0.9
51 INT158000 Binding of APLNR 1 4 0.21 0.2 0.9
52 INT169764 Positive_regulation of Mir16-1 1 1 0.56 0 0.77
53 INT169766 Negative_regulation of S100a1 1 1 0.15 0 0.77
54 INT169760 Negative_regulation of Mir16-1 1 1 0.47 0 0.77
55 INT169767 Positive_regulation of Gene_expression of Mir16-1 1 1 0.38 0 0.75
56 INT133639 Positive_regulation of Gene_expression of Dbh 1 1 0.50 0 0.75
57 INT169761 Regulation of Gene_expression of Mir16-1 1 1 0.22 0 0.63
58 INT118549 Negative_regulation of Phosphorylation of Glyr1 1 1 0.32 0.35 0.54
59 INT118550 Phosphorylation of Glyr1 1 1 0.61 0.35 0.53
60 INT110772 Binding of Tjp1 1 2 0.32 1.12 0.3
61 INT132377 Negative_regulation of Binding of Nos2 1 5 0.29 0.75 0.28
62 INT169701 Positive_regulation of Gene_expression of Fam38a 2 1 0.50 0.33 0.16
63 INT169702 Positive_regulation of Gene_expression of Fam38b 2 1 0.69 0.33 0.16
64 INT110775 Binding of AMICA1 1 1 0.14 0.56 0.1
65 INT169700 Gene_expression of Fam38a 1 1 0.78 0.17 0.08
66 INT169699 Gene_expression of Fam38b 1 1 0.77 0.17 0.08
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