P:COX2

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This page displays the top molecular interactions and top single events that were mentioned in the literature for COX2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for COX2. They are ordered first by their pain relevance and then by number of times they were reported for COX2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1 1.65
2 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22 0.87
3 INT253475 Ncapg2 Positive_regulation of Gene_expression of Fpr3 1 0.21 3.11 0.47 0.69
4 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 0.66
5 INT253482 H37 Positive_regulation of Gene_expression of Gopc 1 0.00 3.99 0.4 0.63
6 INT267123 ROS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.01 1.05 0.31 0.62
7 INT253469 H37 Negative_regulation of Gene_expression of Gopc 1 0.00 1.5 0.31 0.62
8 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54 0.60
9 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77 0.60
10 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73 0.59
11 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24 0.56
12 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28 0.56
13 INT253473 Ncapg2 Positive_regulation of Gene_expression of Gopc 1 0.08 1.26 0.27 0.53
14 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54 0.51
15 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54 0.50
16 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56 0.49
17 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55 0.49
18 INT196879 Cpox Negative_regulation of Gene_expression of Tbxa2r 1 0.04 0.8 0.56 0.49
19 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46 0.48
20 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46 0.48
21 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03 0.45
22 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57 0.42
23 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5 0.42
24 INT253485 Fpr3 Regulation of Gene_expression of Ptger2 1 0.10 2.87 0.17 0.34
25 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 0.34
26 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59 0.31
27 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59 0.31
28 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 0.29
29 INT126385 Ptger2 Positive_regulation of Positive_regulation of Il6 1 0.01 0.07 0.35 0.27
30 INT253467 H37 Positive_regulation of Fpr3 1 0.00 1.27 0.13 0.27
31 INT253486 H37 Positive_regulation of Gene_expression of Fpr3 1 0.00 1.17 0.13 0.26
32 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 0.26
33 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44 0.24
34 INT253476 Ptger2 Negative_regulation of Fpr3 1 0.14 1.22 0.12 0.24
35 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97 0.23
36 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 0.20
37 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 0.20
38 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 0.20
39 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76 0.20
40 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71 0.20
41 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3 0.20
42 INT142450 B4GALNT1 Regulation of Gene_expression of PTGIS 1 0.02 0.24 0.27 0.20
43 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27 0.20
44 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19 0.20
45 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 0.20
46 INT168809 Nfkb1 Positive_regulation of Transcription of Trub1 1 0.02 0.44 0.28 0.20
47 INT145015 CREB5 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.06 0.51 0.22 0.20
48 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 0.20
49 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26 0.20
50 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26 0.20
51 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22 0.20
52 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22 0.20
53 INT159593 Regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.38 0.46 0.74 0.20
54 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19 0.20
55 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25 0.19
56 INT141109 Sftpa1 Positive_regulation of Mapk1 1 0.77 0.65 0.27 0.18
57 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67 0.17
58 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09 0.17
59 INT294116 CIITA Regulation of Gene_expression of HLA-E 1 0.05 0.05 0.08 0.17
60 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49 0.15
61 INT253487 Ncapg2 Positive_regulation of Fpr3 1 0.21 0.73 0.08 0.15
62 INT321826 Stat3 Positive_regulation of Localization of CSF2 1 0.02 0 0.12 0.12
63 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64 0.12
64 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4 0.12
65 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51 0.11
66 INT197113 RETNLB Regulation of IL1B 1 0.00 1.27 0.44 0.11
67 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 0.11
68 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52 0.11
69 INT355583 Binding of EGFR and ANGPTL4 1 0.12 2.14 0.05 0.10
70 INT355589 Binding of EGFR and LTBP1 1 0.11 2.15 0.05 0.10
71 INT355586 Binding of LTBP1 and ANGPTL4 1 0.10 2.15 0.05 0.10
72 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 0.10
73 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 0.10
74 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 0.10
75 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 0.10
76 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58 0.10
77 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55 0.10
78 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49 0.10
79 INT145433 Binding of CPOX and HMOX2 1 0.01 0.42 0.49 0.10
80 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47 0.10
81 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47 0.10
82 INT157150 Positive_regulation of PTGIR Negative_regulation of Gene_expression of TNF 1 0.12 0.97 0.34 0.10
83 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33 0.10
84 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31 0.10
85 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31 0.10
86 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31 0.10
87 INT107615 IL1B Positive_regulation of PTGES 2 0.55 0.05 0.26 0.10
88 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26 0.10
89 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25 0.10
90 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24 0.10
91 INT102620 PTAFR Regulation of Gene_expression of IL6 1 0.24 0.29 0.24 0.10
92 INT102622 PTAFR Regulation of IL6 1 0.24 0.29 0.24 0.10
93 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24 0.10
94 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23 0.10
95 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21 0.10
96 INT92580 IGF2 Positive_regulation of Gene_expression of PTGER2 1 0.07 0.43 0.15 0.10
97 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15 0.10
98 INT92583 IGF2 Positive_regulation of Transcription of PTGER2 1 0.07 0.43 0.15 0.10
99 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15 0.10
100 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05 0.10
101 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05 0.10
102 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05 0.10
103 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62 0.10
104 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41 0.10
105 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24 0.10
106 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15 0.10
107 INT124261 Jun Regulation of Gene_expression of Cpox 1 0.13 0.44 0.32 0.10
108 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32 0.10
109 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21 0.10
110 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87 0.10
111 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24 0.10
112 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54 0.10
113 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14 0.10
114 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52 0.10
115 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79 0.10
116 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51 0.10
117 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31 0.10
118 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9 0.10
119 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 0.05 0.27 0.13 0.10
120 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13 0.10
121 INT141113 Sftpa1 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.46 0.32 0.14 0.10
122 INT141110 Negative_regulation of Sftpa1 Positive_regulation of Mapk1 1 0.47 0.31 0.14 0.10
123 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14 0.10
124 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39 0.10
125 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14 0.10
126 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 0.09
127 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 0.09
128 INT144043 IL13 Positive_regulation of PTGES 1 0.32 0.43 0.37 0.09
129 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37 0.09
130 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18 0.09
131 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17 0.09
132 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22 0.09
133 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37 0.09
134 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46 0.09
135 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3 0.09
136 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07 0.09
137 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46 0.09
138 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46 0.09
139 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9 0.09
140 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 0.09
141 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46 0.09
142 INT254230 Ik Negative_regulation of Gene_expression of TNF 1 0.00 1.29 0.65 0.08
143 INT197112 Binding of IL1B and TP53TG3 1 0.03 1.17 0.31 0.08
144 INT195122 Il1 Positive_regulation of Gene_expression of Gtf3a 1 0.02 1.38 0.5 0.08
145 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14 0.08
146 INT222183 Binding of HDLBP and PLA2G15 1 0.01 0.7 0.57 0.08
147 INT176623 Binding of PTGER2 and NDRG1 1 0.00 0.1 0.16 0.08
148 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95 0.08
149 INT166787 CD44 Negative_regulation of Gene_expression of PTGER1 1 0.04 0.15 0.2 0.08
150 INT166791 CD44 Positive_regulation of Gene_expression of PTGER1 1 0.05 0.15 0.2 0.08
151 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42 0.08
152 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42 0.08
153 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33 0.08
154 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33 0.08
155 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33 0.08
156 INT324527 PGE Positive_regulation of Egfr Positive_regulation of Phosphorylation of Egfr 1 0.38 1.05 0.33 0.08
157 INT144046 IL13 Negative_regulation of Gene_expression of PTGES 1 0.30 0.48 0.35 0.08
158 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35 0.08
159 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35 0.08
160 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35 0.08
161 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35 0.08
162 INT266660 PTGER2 Positive_regulation of Gene_expression of MMP9 1 0.06 0.08 0.12 0.08
163 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15 0.08
164 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 0.44 0.54 0.18 0.07
165 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18 0.07
166 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18 0.07
167 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18 0.07
168 INT196886 Ly6 Positive_regulation of Binding of Ly6 and Prkca 1 0.00 0.18 0.25 0.07
169 INT196880 Binding of Ly6 and Prkca 1 0.01 0.18 0.25 0.07
170 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 0.07
171 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42 0.07
172 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 0.07
173 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57 0.07
174 INT171261 IL8 Positive_regulation of MMP1 1 0.04 0.05 0.07 0.06
175 INT171275 IL8 Positive_regulation of PTGER2 1 0.01 0.05 0.07 0.06
176 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 0.06
177 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35 0.06
178 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31 0.06
179 INT197115 Binding of MCF2 and RETNLB 1 0.00 1.06 0.7 0.06
180 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11 0.05
181 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03 0.05
182 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31 0.05

Single Events

The table below shows the top 200 pain related interactions that have been reported for COX2. They are ordered first by their pain relevance and then by number of times they were reported in COX2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 1.29
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 1.81
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 0.08
4 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 4.88
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 0.85
6 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 0.59
7 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 0.18
8 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 0.08
9 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 0.10
10 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 4.73
11 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 0.20
12 INT2649 Regulation of Calca 433 0.62 146.05 330.95 0.13
13 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 0.44
14 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 24.29
15 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 0.24
16 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 2.00
17 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 0.10
18 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 4.56
19 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 0.23
20 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 0.57
21 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 2.09
22 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 4.16
23 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 0.10
24 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 0.45
25 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 0.43
26 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 0.25
27 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 0.20
28 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 3.58
29 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.24
30 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 1.94
31 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 1.91
32 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 0.50
33 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 0.28
34 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 0.54
35 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 0.55
36 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 4.26
37 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 0.26
38 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 0.08
39 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 2.87
40 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 3.83
41 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 3.62
42 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 0.38
43 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 0.80
44 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 0.08
45 INT812 Localization of INS 1026 0.81 515.6 145.31 0.10
46 INT9660 Regulation of TNF 363 0.62 312.94 139.99 0.10
47 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 0.06
48 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 0.10
49 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 2.54
50 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 1.15
51 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 0.20
52 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 1.61
53 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 0.12
54 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 0.46
55 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 0.10
56 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 1.01
57 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 0.75
58 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 18.30
59 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 0.07
60 INT12339 Localization of IL8 437 0.81 251.87 117.39 0.37
61 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 0.15
62 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 0.58
63 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 0.20
64 INT90 Localization of Gast 400 0.81 137.67 113 0.20
65 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 0.38
66 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 0.08
67 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 0.07
68 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 0.24
69 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 3.02
70 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 4.11
71 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 0.17
72 INT12082 Localization of IL6 365 0.81 241.78 105.78 0.63
73 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 0.98
74 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 0.84
75 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 0.39
76 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 1.10
77 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 0.18
78 INT65500 Gene_expression of App 605 0.78 429.94 98.31 0.65
79 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 2.76
80 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 1.38
81 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 0.06
82 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 1.00
83 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 0.08
84 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 1.31
85 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 1.93
86 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 0.07
87 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 0.16
88 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 1.45
89 INT10166 Localization of Tnf 237 0.81 153.95 88.64 0.37
90 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 0.09
91 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 0.51
92 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 0.37
93 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 0.62
94 INT73340 Negative_regulation of Faah 134 0.59 38.67 85.03 0.81
95 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 0.09
96 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 4.12
97 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 0.18
98 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 0.79
99 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 0.49
100 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 1.87
101 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 0.48
102 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 2.02
103 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 0.16
104 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 0.20
105 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 0.20
106 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 0.16
107 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 0.10
108 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 0.25
109 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 7.03
110 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 0.10
111 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 0.15
112 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 0.80
113 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96 0.10
114 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 0.05
115 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 0.07
116 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 2.48
117 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 0.06
118 INT6849 Localization of IL1B 229 0.81 112.56 69.63 2.01
119 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 0.09
120 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 0.05
121 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 0.11
122 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 0.20
123 INT19511 Localization of Il6 212 0.81 118.17 67.67 2.40
124 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 0.13
125 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 0.08
126 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 6.56
127 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 0.13
128 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 0.24
129 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 0.09
130 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 0.10
131 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 0.12
132 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 0.21
133 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 0.06
134 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 0.35
135 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 2.32
136 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 0.47
137 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 0.09
138 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 0.09
139 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 0.18
140 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.71
141 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 2.31
142 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 0.15
143 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 0.40
144 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 0.09
145 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 0.18
146 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 0.79
147 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 0.51
148 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 0.20
149 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 0.67
150 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 0.10
151 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 0.10
152 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 3.78
153 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 0.86
154 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 0.05
155 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 0.10
156 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 0.10
157 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 1.11
158 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 1.78
159 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 0.19
160 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 1.48
161 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 0.10
162 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 7.87
163 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 0.20
164 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 0.32
165 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 0.07
166 INT122041 Binding of Ppara 308 0.48 189.17 51.48 0.97
167 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 0.07
168 INT19775 Localization of Il1 183 0.78 145.5 50.91 0.09
169 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 0.09
170 INT8690 Localization of Tac1 71 0.80 22.98 50.75 0.10
171 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 0.09
172 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 8.05
173 INT9210 Regulation of IL6 166 0.62 125.61 49.95 0.10
174 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 1.40
175 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64 0.10
176 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 0.20
177 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 0.20
178 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 0.10
179 INT654 Localization of REN 250 0.81 75.12 47.86 0.10
180 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 0.10
181 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 0.42
182 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 0.54
183 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 0.18
184 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 0.10
185 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 0.08
186 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 0.30
187 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 0.12
188 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 0.48
189 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 1.05
190 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 1.86
191 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 0.09
192 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 0.26
193 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 0.20
194 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 1.01
195 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 0.83
196 INT13354 Transcription of TNF 108 0.72 85.81 42.32 0.10
197 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 0.40
198 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 0.85
199 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 0.10
200 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 0.05
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