P:Central grey

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pChart

Pain Term
Category Anatomy
Synonyms Periaqueductal Gray, Periaqueductal Grey, Periaqueductyl Gray, Periaqueductyl Grey
Pain Specific No
Documents 1569
Hot Single Events 200
Hot Interactions 113

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Central grey. They are ordered first by their pain relevance and then by number of times they were reported for Central grey. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63 100.00
2 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99 100.00
3 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99 100.00
4 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24 100.00
5 INT107029 Cpox Regulation of Pag1 1 0.01 1.24 1.15 100.00
6 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13 100.00
7 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2 100.00
8 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2 100.00
9 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2 100.00
10 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38 100.00
11 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38 100.00
12 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38 100.00
13 INT53847 Pag1 Regulation of Gabrd 1 0.01 1 1.08 100.00
14 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64 100.00
15 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62 100.00
16 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92 100.00
17 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65 100.00
18 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65 100.00
19 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06 100.00
20 INT53843 Penk Regulation of Pag1 1 0.07 0.9 1.01 100.00
21 INT53846 Positive_regulation of Penk Regulation of Pag1 1 0.07 0.9 1.01 100.00
22 INT53844 Penk Regulation of Kitl 1 0.00 0.9 1 100.00
23 INT53845 Positive_regulation of Penk Regulation of Kitl 1 0.00 0.9 1 100.00
24 INT291965 Phex Negative_regulation of Pag1 1 0.05 0.82 0.43 100.00
25 INT25660 Binding of Penk and Pag1 1 0.01 0.67 1.19 100.00
26 INT38422 Zbtb7a Positive_regulation of Pag1 1 0.30 0.66 0.54 100.00
27 INT231968 Binding of Cpn1 and Rvm 1 0.11 1.57 2.45 100.00
28 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44 100.00
29 INT38131 Pag1 Negative_regulation of Gsr 1 0.01 0.72 0.58 100.00
30 INT266065 Positive_regulation of Binding of Ceacam3 and PAG1 1 0.03 1.44 0.63 100.00
31 INT266062 Binding of Ceacam3 and PAG1 1 0.02 1.44 0.63 100.00
32 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04 100.00
33 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19 100.00
34 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17 100.00
35 INT46892 Positive_regulation of Binding of Pag1 and Nrm 1 0.01 0.61 0.63 100.00
36 INT144062 Grm8 Regulation of Localization of Pag1 1 0.21 0.63 0.79 100.00
37 INT46891 Binding of Pag1 and Nrm 1 0.01 0.61 0.63 100.00
38 INT107030 Cpox Regulation of Cpox Regulation of Pag1 1 0.01 0.62 0.57 100.00
39 INT37874 Positive_regulation of Pag1 Regulation of Nrm 1 0.04 0.59 0.71 100.00
40 INT37873 Pag1 Regulation of Nrm 2 0.04 1.1 2.41 100.00
41 INT2428 Pag1 Regulation of Kitl 1 0.00 0.41 0.38 100.00
42 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3 100.00
43 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3 100.00
44 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48 100.00
45 INT266063 PAG1 Regulation of Gene_expression of Creb1 1 0.06 0.53 0.12 100.00
46 INT132696 Binding of Arc and Pag1 1 0.00 0.5 0.67 100.00
47 INT53842 Abat Regulation of Gabrd 1 0.04 1 1.08 99.96
48 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62 99.96
49 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17 99.84
50 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43 99.68
51 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97 99.54
52 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52 99.52
53 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52 99.52
54 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52 99.52
55 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01 99.44
56 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19 99.42
57 INT141171 Ptz1a Positive_regulation of Gene_expression of Fos 1 0.07 0.5 0.69 99.20
58 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15 99.12
59 INT134584 Arrb2 Regulation of Arrb2 Regulation of Oprm1 1 0.19 0.62 1.07 98.64
60 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44 98.60
61 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26 98.44
62 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34 98.32
63 INT231967 Binding of Psmd1 and Cpn1 1 0.06 1.39 2.25 98.28
64 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86 98.12
65 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25 98.12
66 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 98.12
67 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61 98.00
68 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51 98.00
69 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4 98.00
70 INT35982 LH Negative_regulation of tf 1 0.03 0.18 0.77 97.20
71 INT34472 Penk Regulation of Slc3a1 2 0.03 0.42 1.74 96.84
72 INT68540 Penk Regulation of Ndst4 1 0.00 0.35 0.5 96.84
73 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66 96.56
74 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25 96.40
75 INT33314 Binding of Ap1m1 and Ap1m2 1 0.07 0.97 5.42 96.24
76 INT121000 Binding of PAG1 and Nrm 1 0.13 0.67 1.25 96.04
77 INT99160 Binding of Mpo and Nrm 1 0.38 0.92 0.45 95.76
78 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06 95.76
79 INT105786 Positive_regulation of Binding of SGCG and Nts 1 0.22 0.31 0.59 95.40
80 INT105787 Binding of SGCG and Nts 1 0.17 0.31 0.59 95.40
81 INT101966 Pnoc Positive_regulation of Kcnj9 1 0.14 0.26 0.46 94.64
82 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23 94.24
83 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01 94.12
84 INT338391 Thim Positive_regulation of Cpb2 1 0.08 0.37 0.19 94.08
85 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72 92.68
86 INT126303 Binding of Rgs7 and Pag1 1 0.15 0.41 0.72 92.44
87 INT126305 Binding of Rgs10 and Pag1 1 0.16 0.41 0.72 92.20
88 INT126306 Binding of Rgs11 and Pag1 1 0.18 0.41 0.72 91.80
89 INT99159 Nrm Positive_regulation of Mpo 1 0.44 0.85 0.36 91.52
90 INT124158 Binding of Oprm1 and Rgs7 1 0.30 0.18 0.62 91.20
91 INT124161 Binding of Rgs7 and Rgs11 1 0.29 0.18 0.62 91.20
92 INT124159 Binding of Oprm1 and Rgs11 1 0.31 0.18 0.62 90.84
93 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89 90.24
94 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92 90.24
95 INT264931 Binding of Gnaz and Hrh1 1 0.01 0.83 1.12 90.04
96 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65 89.44
97 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8 89.16
98 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 88.72
99 INT158752 Binding of TRPV1 and Rvm 1 0.05 1.6 3.1 88.24
100 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08 88.24
101 INT123453 Binding of POMC and Penk 1 0.01 0.31 1.23 88.16
102 INT69770 Penk Negative_regulation of Pscs 1 0.11 0.22 3.39 86.24
103 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11 86.20
104 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18 85.20
105 INT116753 Ngf Regulation of Pik3cd 1 0.40 0.29 0.63 83.76
106 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63 83.76
107 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26 83.36
108 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24 83.36
109 INT255710 Binding of INS and LOC691138 1 0.00 0.51 0.12 83.08
110 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05 81.36
111 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58 81.36
112 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18 81.36
113 INT43058 Pomc Regulation of Localization of Rhd 1 0.03 0.19 0.45 80.04
114 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72 78.00
115 INT338392 Thim Negative_regulation of Mors1 1 0.01 0.4 0.69 76.92
116 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21 76.80
117 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05 76.48
118 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05 76.48
119 INT61675 Binding of Gpm6a and Man2a2 1 0.00 0.08 1.67 76.04
120 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15 75.92
121 INT131314 crz Regulation of Oprl1 1 0.06 0.08 1.08 75.52
122 INT61165 Binding of Pag1 and Pcyt1a 1 0.01 0.33 0.73 75.00
123 INT61164 Binding of Pomc and Pcyt1a 1 0.17 0.24 0.61 75.00
124 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48 73.60
125 INT61674 Gpm6a Regulation of Oprd1 1 0.01 0.07 1.62 72.96
126 INT124160 Binding of Rgs9 and Mors1 1 0.23 0.28 0.9 72.36
127 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52 72.16
128 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55 71.44
129 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55 71.04
130 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66 70.16
131 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64 70.16
132 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 0.03 0.13 3.64 65.72
133 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 0.44 0.13 0.62 65.12
134 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85 63.88
135 INT119548 Fos Regulation of Gene_expression of Nfe2l2 1 0.48 0.47 0.25 63.04
136 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 62.28
137 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3 60.00
138 INT307046 Tmie Positive_regulation of Cnr1 1 0.05 0.31 0.69 60.00
139 INT158809 Pag1 Regulation of Rvm 1 0.02 1.28 2.33 58.84
140 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49 51.96
141 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48 51.96
142 INT236338 Negative_regulation of Binding of PCSK1 and GOPC 1 0.06 0.19 0.2 50.12
143 INT236339 Binding of PCSK1 and GOPC 1 0.05 0.14 0.17 50.00
144 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12 49.08
145 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12 49.08
146 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 45.68
147 INT102841 Pdcl Regulation of Oprd1 1 0.02 0.12 0.77 44.40
148 INT98379 Regulation of Binding of Pomc and Oprd1 1 0.01 0.35 0.23 44.20
149 INT98380 Binding of Pomc and Oprd1 1 0.02 0.35 0.23 44.20
150 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45 43.20
151 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 41.20
152 INT185515 Binding of Igf1 and Csf2 1 0.29 0.4 0.15 38.84
153 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1 35.16
154 INT348403 FDPS Negative_regulation of FDPS Negative_regulation of Fdps 1 0.03 0.79 0.71 34.64
155 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12 31.12
156 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92 27.80
157 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92 27.80
158 INT71070 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Cck 1 0.26 0 1.24 25.00
159 INT6409 Binding of NFKBIL1 and Oprm1 1 0.00 0 0.8 25.00
160 INT6408 Binding of NFKBIL1 and Ap1m2 1 0.00 0 0.8 25.00
161 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49 25.00
162 INT218840 Cysltr1 Positive_regulation of Ltp 2 0.02 1.04 1.06 24.84
163 INT296299 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Rbm39 1 0.00 0.59 0.79 19.28
164 INT296297 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Car2 1 0.01 0.59 0.77 19.28
165 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78 17.56
166 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1 16.32
167 INT290821 CRX Positive_regulation of Cort 1 0.14 0.51 0.41 12.72
168 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14 12.56
169 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14 12.56
170 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94 12.24
171 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65 5.00
172 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
173 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6 5.00
174 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18 5.00
175 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
176 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88 5.00
177 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
178 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08 5.00
179 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07 5.00
180 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01 5.00
181 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
182 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
183 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 5.00
184 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78 5.00
185 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71 5.00
186 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71 5.00
187 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
188 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
189 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
190 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
191 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
192 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57 5.00
193 INT245347 Binding of Penk and Vta1 1 0.05 0.14 1.53 5.00
194 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
195 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
196 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
197 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
198 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
199 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
200 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Central grey. They are ordered first by their pain relevance and then by number of times they were reported in Central grey. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
2 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79 100.00
3 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 100.00
4 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
5 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 100.00
6 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 100.00
7 INT7800 Localization of Pag1 51 0.56 33.06 53.74 100.00
8 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 100.00
9 INT254567 Positive_regulation of Gene_expression of PAG1 10 0.39 31.15 24.26 100.00
10 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29 100.00
11 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
12 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
13 INT19580 Binding of Pag1 24 0.30 15.13 20.88 100.00
14 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 100.00
15 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
16 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52 100.00
17 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
18 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 100.00
19 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 100.00
20 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 100.00
21 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 100.00
22 INT42459 Positive_regulation of Gene_expression of Pag1 19 0.25 13.49 12.22 100.00
23 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 100.00
24 INT21934 Negative_regulation of Negative_regulation of Pag1 11 0.39 7.91 11.37 100.00
25 INT254566 Negative_regulation of Gene_expression of PAG1 7 0.33 9.51 9.91 100.00
26 INT99058 Regulation of PAG1 18 0.45 21.62 18.5 100.00
27 INT28857 Negative_regulation of Positive_regulation of Pag1 11 0.30 8.46 10.19 100.00
28 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
29 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 100.00
30 INT66868 Positive_regulation of Ceacam3 40 0.69 26.61 28.9 100.00
31 INT81419 Localization of PAG1 10 0.64 11.1 8.01 100.00
32 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89 100.00
33 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
34 INT66867 Gene_expression of Ceacam3 58 0.67 30.44 40.7 100.00
35 INT7801 Positive_regulation of Localization of Pag1 7 0.32 5.96 8.67 100.00
36 INT63553 Binding of PAG1 14 0.48 12.51 14.76 100.00
37 INT254570 Regulation of Gene_expression of PAG1 3 0.35 6.72 5.76 100.00
38 INT118905 Positive_regulation of Positive_regulation of PAG1 8 0.40 7.55 12.25 100.00
39 INT21967 Positive_regulation of Positive_regulation of Pag1 5 0.31 5.72 6.86 100.00
40 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 100.00
41 INT38130 Negative_regulation of Gene_expression of Pag1 8 0.28 6.16 7.99 100.00
42 INT112338 Localization of Rvm 11 0.31 9.51 17.61 100.00
43 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07 100.00
44 INT51320 Regulation of Localization of Pag1 4 0.17 3.34 6.15 100.00
45 INT21933 Regulation of Negative_regulation of Pag1 5 0.28 5.48 5.29 100.00
46 INT114578 Positive_regulation of Gene_expression of Ceacam3 18 0.47 14.95 12.22 100.00
47 INT477 Localization of Avp 813 0.81 131.58 300.4 100.00
48 INT32596 Regulation of Gene_expression of Il2 13 0.61 6.85 7.83 100.00
49 INT1209 Binding of Kitl 14 0.37 6.72 4.3 100.00
50 INT101193 Regulation of Gene_expression of Pag1 13 0.22 8.62 6.77 100.00
51 INT7524 Localization of Kitl 9 0.74 3.45 5.49 100.00
52 INT1613 Binding of Nts 58 0.48 10.55 28.18 100.00
53 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47 100.00
54 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19 100.00
55 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 100.00
56 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 100.00
57 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06 100.00
58 INT27805 Regulation of Avpr1a 5 0.60 3.11 5.19 100.00
59 INT38421 Positive_regulation of Zbtb7a 2 0.50 1.52 1.86 100.00
60 INT266051 Phosphorylation of PAG1 1 0.10 2.51 1.11 100.00
61 INT92716 Negative_regulation of PAG1 6 0.51 5.82 6.32 100.00
62 INT266050 Regulation of Binding of PAG1 1 0.06 2.96 1.25 100.00
63 INT166814 Transcription of Pag1 5 0.46 3.95 3.71 100.00
64 INT260159 Negative_regulation of Positive_regulation of PAG1 2 0.33 1.86 3.39 100.00
65 INT88255 Regulation of Positive_regulation of Kitl 2 0.00 1.72 3.47 100.00
66 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24 100.00
67 INT7287 Positive_regulation of Transcription of Penk 103 0.70 19.81 50.37 100.00
68 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99 100.00
69 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93 100.00
70 INT83325 Regulation of Gene_expression of Il2ra 8 0.48 3.59 2.36 100.00
71 INT132682 Phosphorylation of Pag1 7 0.71 5.61 5.75 100.00
72 INT13352 Regulation of Kitl 11 0.45 3.91 6.07 100.00
73 INT166815 Negative_regulation of Localization of Pag1 2 0.10 1.8 1.95 100.00
74 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 100.00
75 INT110291 Regulation of Ceacam3 8 0.61 7 8.24 100.00
76 INT139401 Binding of Ceacam3 2 0.37 2.32 2.17 100.00
77 INT255708 Transcription of PAG1 2 0.53 0.84 2.08 100.00
78 INT22630 Positive_regulation of Binding of Cck 4 0.48 2.27 5.92 100.00
79 INT20028 Positive_regulation of Gene_expression of Ghrh 9 0.50 1.52 2.62 100.00
80 INT6928 Regulation of Tfpi 4 0.26 1.06 2.61 100.00
81 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4 100.00
82 INT83328 Regulation of Gene_expression of Cd4 6 0.43 2.55 1.42 100.00
83 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 100.00
84 INT83330 Regulation of Gene_expression of Cd8a 1 0.23 0.88 1.16 100.00
85 INT18456 Positive_regulation of Transcription of Sst 5 0.49 1.09 3.78 100.00
86 INT35425 Positive_regulation of Transcription of Gpi 2 0.10 0.75 1.01 100.00
87 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 100.00
88 INT260160 Regulation of Positive_regulation of PAG1 1 0.35 1.1 1.4 100.00
89 INT28735 Localization of Reln 2 0.12 1.49 1.7 100.00
90 INT88961 Positive_regulation of Negative_regulation of Pag1 1 0.24 1.05 0.6 100.00
91 INT63912 Regulation of Negative_regulation of Kitl 1 0.00 0.59 0.77 100.00
92 INT118358 Regulation of Regulation of Pag1 3 0.32 1.77 1.43 100.00
93 INT50968 Regulation of Zbtb7a 1 0.38 0.51 0.74 100.00
94 INT39577 Regulation of Lss 1 0.08 0.5 0.85 100.00
95 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22 100.00
96 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33 100.00
97 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
98 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21 100.00
99 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68 100.00
100 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 100.00
101 INT255704 Positive_regulation of Transcription of PAG1 1 0.06 0.35 0.21 100.00
102 INT50990 Regulation of Cpb2 12 0.37 2.71 7.07 100.00
103 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64 100.00
104 INT162547 Negative_regulation of Binding of Pag1 1 0.16 0.64 1.61 100.00
105 INT162546 Positive_regulation of Binding of Pag1 1 0.19 0.63 1.6 100.00
106 INT165449 Negative_regulation of Gene_expression of Ceacam3 5 0.36 2.47 3.45 100.00
107 INT254569 Regulation of Localization of PAG1 2 0.20 3.08 1.23 100.00
108 INT263969 Negative_regulation of Localization of PAG1 1 0.36 2.72 0.61 100.00
109 INT263967 Positive_regulation of Localization of PAG1 1 0.43 2.83 0.61 100.00
110 INT7715 Regulation of Drd2 35 0.62 10.79 22.3 100.00
111 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04 100.00
112 INT72615 Negative_regulation of Rcor2 1 0.32 0.17 1.24 100.00
113 INT39804 Positive_regulation of gt 1 0.01 0.1 0.86 100.00
114 INT259517 Positive_regulation of Localization of Ps 1 0.03 0.43 0.36 100.00
115 INT98942 Gene_expression of Dtd1 1 0.52 0.36 0.3 100.00
116 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.98
117 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96 99.98
118 INT292 Localization of Penk 876 0.81 88.44 669.14 99.98
119 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 99.98
120 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.98
121 INT5033 Negative_regulation of tf 39 0.54 13.37 48.62 99.98
122 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 99.98
123 INT91979 Positive_regulation of Positive_regulation of Nkx1-1 3 0.23 2.06 3.06 99.98
124 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98 99.98
125 INT84796 Positive_regulation of Binding of 2 0.46 0.66 1.39 99.98
126 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72 99.96
127 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 99.96
128 INT19582 Binding of NPHS1 1 0.02 0.28 0.4 99.96
129 INT19581 Regulation of NPHS1 3 0.25 2.38 0.5 99.96
130 INT1396 Binding of Penk 355 0.48 22.79 269.65 99.92
131 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34 99.92
132 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 99.92
133 INT10520 Regulation of Rvm 20 0.24 10.15 20.52 99.92
134 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25 99.92
135 INT64447 Transcription of Mc4r 14 0.61 6.08 15.29 99.92
136 INT64445 Gene_expression of Mc4r 17 0.78 5.06 12.91 99.92
137 INT64449 Negative_regulation of Gene_expression of Mc4r 7 0.58 2 7.86 99.92
138 INT64446 Negative_regulation of Transcription of Mc4r 4 0.43 1.01 4.8 99.92
139 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31 99.92
140 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 99.90
141 INT41230 Gene_expression of Nrm 16 0.67 6.37 21.67 99.90
142 INT132686 Positive_regulation of Phosphorylation of NTRK2 1 0.13 0.98 1.06 99.90
143 INT132684 Phosphorylation of NTRK2 1 0.21 0.97 1.04 99.90
144 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.88
145 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 99.86
146 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91 99.84
147 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 99.84
148 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 99.84
149 INT1308 Localization of Pomc 457 0.81 66.83 217.5 99.84
150 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77 99.84
151 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75 99.84
152 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.84
153 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 99.84
154 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.84
155 INT44745 Localization of Nrm 5 0.65 2.04 4.92 99.84
156 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38 99.84
157 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 99.84
158 INT108940 Transcription of Arrb1 1 0.47 0.3 3.08 99.84
159 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73 99.84
160 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1 99.84
161 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84 99.84
162 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 99.82
163 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 99.82
164 INT73340 Negative_regulation of Faah 134 0.59 38.67 85.03 99.82
165 INT21747 Localization of crf 8 0.47 5.32 5.06 99.82
166 INT74674 Transcription of TAC1 7 0.67 1 3.01 99.82
167 INT155407 Transcription of crf 1 0.04 0.91 1.04 99.82
168 INT255705 Transcription of C12orf39 1 0.69 0.75 0.37 99.82
169 INT255706 Positive_regulation of Transcription of C12orf39 1 0.67 0.35 0.21 99.82
170 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 99.78
171 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92 99.76
172 INT2366 Binding of Cck 192 0.48 30.64 163.46 99.76
173 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03 99.74
174 INT81415 Gene_expression of Gabrp 2 0.30 1.49 1.84 99.74
175 INT22170 Negative_regulation of D1Jor3 23 0.38 3.54 9.16 99.72
176 INT894 Binding of Avp 84 0.48 29.16 29.63 99.72
177 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 99.72
178 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 99.70
179 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 99.70
180 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.70
181 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.70
182 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.68
183 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 99.68
184 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 99.68
185 INT8363 Localization of Nts 135 0.81 14.29 61.71 99.68
186 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.68
187 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 99.68
188 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 99.68
189 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 99.68
190 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 99.68
191 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37 99.68
192 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.68
193 INT12231 Positive_regulation of Localization of Nts 17 0.70 4.54 13.85 99.68
194 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 99.68
195 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 99.68
196 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 99.68
197 INT1463 Binding of Pomc 129 0.48 15.89 56.27 99.68
198 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78 99.68
199 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 99.68
200 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 99.68
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