P:Medulla

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This page displays the top molecular interactions and top single events that were mentioned in the literature for Medulla. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Medulla. They are ordered first by their pain relevance and then by number of times they were reported for Medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23 1.80
2 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56 1.63
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52 1.38
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5 1.38
5 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27 1.36
6 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39 1.30
7 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34 1.30
8 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92 1.12
9 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57 1.12
10 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34 1.05
11 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34 1.05
12 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33 1.05
13 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33 1.05
14 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64 1.03
15 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1 1.03
16 INT91539 Pomc Positive_regulation of Pomc Positive_regulation of P9Ehs1 1 0.03 0.84 3.13 1.00
17 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8 0.89
18 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74 0.88
19 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09 0.69
20 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23 0.68
21 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02 0.62
22 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67 0.59
23 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 0.55
24 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59 0.46
25 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59 0.46
26 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95 0.44
27 INT253826 Cck Regulation of Nts 1 0.21 0.36 0.94 0.44
28 INT84085 Binding of Gucy1a2 and Nisch 1 0.00 0.22 0.35 0.42
29 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35 0.41
30 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56 0.41
31 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 0.41
32 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 0.39
33 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46 0.38
34 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35 0.38
35 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35 0.38
36 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35 0.38
37 INT14621 Gal Regulation of Npy 1 0.30 0 0.7 0.38
38 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16 0.38
39 INT354235 Aif1 Regulation of P2ry12 1 0.20 0.49 0.45 0.37
40 INT146240 Binding of AP1B1 and Mrgprc 1 0.08 0.82 0.85 0.35
41 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55 0.35
42 INT105422 Fosl2 Positive_regulation of Gene_expression of Penk 1 0.31 0 0.55 0.35
43 INT105421 Fos Positive_regulation of Gene_expression of Penk 1 0.54 0 0.55 0.35
44 INT135498 Binding of YY1 and MRGPRX4 1 0.00 0.2 0.62 0.35
45 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95 0.35
46 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63 0.34
47 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34 0.33
48 INT88445 Uncx Positive_regulation of Gene_expression of Penk 1 0.10 0 0.17 0.33
49 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94 0.33
50 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93 0.33
51 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69 0.33
52 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68 0.33
53 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 0.30
54 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15 0.30
55 INT88447 Uncx Negative_regulation of Binding of Jun 1 0.07 0 0.22 0.30
56 INT158399 Binding of Preb and Frg1 1 0.01 0.3 0.62 0.29
57 INT24336 Negative_regulation of Binding of PRB1 and RTCA 1 0.00 0.1 0.45 0.28
58 INT16933 Tsc22d3 Positive_regulation of Localization of Penk 2 0.24 0 0.76 0.28
59 INT24335 Positive_regulation of Binding of PRB1 and RTCA 1 0.00 0.09 0.44 0.28
60 INT24334 Binding of PRB1 and RTCA 1 0.00 0.09 0.44 0.27
61 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 0.27
62 INT85791 Prlh Regulation of Localization of Prl 1 0.23 0 0.26 0.27
63 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34 0.27
64 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69 0.26
65 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02 0.25
66 INT354306 Binding of Rgs4 and Rgs1 1 0.40 0.36 0.98 0.24
67 INT36733 Positive_regulation of Prn Negative_regulation of Gene_expression of Mtap 1 0.16 0.44 0.28 0.24
68 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66 0.23
69 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41 0.23
70 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41 0.23
71 INT253835 Binding of DST and Fos 1 0.02 0 0.55 0.23
72 INT85792 Prlh Positive_regulation of Localization of Prl 1 0.39 0 0.24 0.23
73 INT253832 Binding of Fos and Nts 1 0.14 0 0.54 0.22
74 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46 0.22
75 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44 0.20
76 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82 0.20
77 INT31276 Oxt Negative_regulation of Cpe 1 0.01 0 0.31 0.20
78 INT31275 Avp Negative_regulation of Cpe 1 0.00 0 0.31 0.20
79 INT31277 Penk Negative_regulation of Cpe 1 0.12 0 0.29 0.20
80 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53 0.20
81 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53 0.20
82 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11 0.20
83 INT119918 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 1.64 0.20
84 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53 0.20
85 INT79593 Binding of Reg1 and LMTK2 1 0.00 0.32 0.53 0.20
86 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03 0.20
87 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26 0.20
88 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32 0.19
89 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72 0.19
90 INT253829 Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72 0.19
91 INT253833 Positive_regulation of Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72 0.19
92 INT61510 Binding of Trh and Gm14673 1 0.01 0 0.48 0.19
93 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 0.19
94 INT144343 Binding of Npffr2 and Qrfp 1 0.37 0 0.37 0.19
95 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84 0.19
96 INT144345 Binding of Qrfpr and Qrfp 1 0.40 0 0.34 0.19
97 INT35982 LH Negative_regulation of tf 1 0.03 0.18 0.77 0.19
98 INT144344 Binding of Npvf and Qrfp 1 0.16 0 0.34 0.18
99 INT66580 Binding of Ap1s1 and Rare2 1 0.00 0.07 0.76 0.18
100 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1 0.18
101 INT35984 Ptger2 Positive_regulation of fut10 1 0.10 0.86 0.14 0.18
102 INT30378 Binding of Sst and Penk 1 0.28 0.52 1.01 0.18
103 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75 0.18
104 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 0.03 0 0.44 0.17
105 INT83869 Oprm1 Regulation of Gene_expression of Fos 1 0.01 0 0.18 0.17
106 INT353630 Binding of Psmd1 and Shbdp1 1 0.02 0 0.76 0.17
107 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12 0.16
108 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08 0.16
109 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94 0.16
110 INT88451 Uncx Regulation of Transcription of Penk 1 0.06 0 0.17 0.16
111 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17 0.16
112 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93 0.16
113 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 0.16
114 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08 0.16
115 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34 0.16
116 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 0.16
117 INT46085 Binding of MET and Penk 1 0.02 0.06 0.83 0.15
118 INT46084 Binding of SELL and Penk 1 0.02 0.06 0.83 0.15
119 INT46076 Binding of MET and SELL 1 0.39 0.06 0.83 0.15
120 INT104162 HTR1D Regulation of Localization of CALCA 1 0.31 0.28 0.58 0.15
121 INT340318 Gopc Regulation of Ntrk2 1 0.24 0.1 0.08 0.15
122 INT106871 Grip2 Regulation of Tacr3 1 0.00 0 0.32 0.15
123 INT10552 Penk Positive_regulation of Regulation of Cebpz 1 0.44 0.25 1.03 0.15
124 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21 0.15
125 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39 0.15
126 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 0.15
127 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31 0.15
128 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21 0.15
129 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05 0.15
130 INT48999 Penk Regulation of Nts 1 0.28 0 0.66 0.15
131 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57 0.15
132 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 0.15
133 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02 0.15
134 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46 0.15
135 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 0.14
136 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12 0.14
137 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55 0.14
138 INT304497 Mknk1 Positive_regulation of Nos1 1 0.19 0.53 0.3 0.14
139 INT304536 Mknk1 Positive_regulation of PRKG1 1 0.03 0.53 0.3 0.14
140 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67 0.14
141 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36 0.14
142 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36 0.13
143 INT135500 Positive_regulation of YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52 0.13
144 INT135501 MRGPRX4 Positive_regulation of YY1 1 0.00 0.06 0.52 0.13
145 INT135497 YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52 0.13
146 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4 0.13
147 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 0.13
148 INT83868 Oprd1 Positive_regulation of Gene_expression of Fos 1 0.01 0 0.75 0.13
149 INT305509 Slc17a7 Positive_regulation of Ex 1 0.05 0.09 0.23 0.13
150 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35 0.13
151 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35 0.13
152 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89 0.13
153 INT135503 MRGPRX4 Regulation of YY1 1 0.01 0.05 0.5 0.13
154 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38 0.12
155 INT165478 Prok2 Positive_regulation of Positive_regulation of Kcnma1 1 0.02 0 0.25 0.11
156 INT334590 IRF6 Positive_regulation of Localization of Ptger2 1 0.00 0 0.15 0.11
157 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23 0.11
158 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92 0.11
159 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11 0.10
160 INT188288 Ghrl Regulation of Gene_expression of Pou1f1 1 0.07 0 0.3 0.10
161 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67 0.10
162 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66 0.10
163 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42 0.10
164 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 0.40 0 0.2 0.10
165 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29 0.10
166 INT37905 Cck Negative_regulation of Binding of Nts 1 0.64 0 0.61 0.10
167 INT37906 Cck Negative_regulation of Nts 1 0.64 0 0.61 0.10
168 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14 0.10
169 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62 0.10
170 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27 0.10
171 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15 0.10
172 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83 0.10
173 INT56181 sch Regulation of Positive_regulation of Nppa 1 0.07 0.08 0.14 0.10
174 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02 0.10
175 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4 0.10
176 INT289049 Binding of Slc38a1 and Sat2 1 0.02 0 0.05 0.10
177 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 0.10
178 INT5217 Binding of GRDX and Tas2r124 1 0.11 0.37 0.05 0.10
179 INT5216 Binding of GRDX and Ighg3 1 0.42 0.37 0.05 0.10
180 INT214165 Agrp Negative_regulation of Localization of Npy 1 0.23 0.06 0.1 0.10
181 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 0.10
182 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 0.10
183 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48 0.10
184 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92 0.10
185 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05 0.09
186 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 0.09
187 INT275802 Hcrt Regulation of Rem1 1 0.20 0.95 0.17 0.09
188 INT257805 Binding of Car3 and Gopc 1 0.18 0 0.25 0.09
189 INT40854 Man2a2 Regulation of Regulation of Eef1a1 1 0.03 0 0.25 0.09
190 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38 0.09
191 INT106547 Oprm1 Regulation of Oprm1 1 0.04 0 0.23 0.09
192 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09 0.09
193 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 0.09
194 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 0.09
195 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 0.09
196 INT214156 Pomc Negative_regulation of Gene_expression of Npy 1 0.39 0.07 0.09 0.09
197 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64 0.09
198 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64 0.09
199 INT122832 AP1B1 Negative_regulation of Gene_expression of FLII 1 0.01 0 0.47 0.09
200 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 0.09

Single Events

The table below shows the top 200 pain related interactions that have been reported for Medulla. They are ordered first by their pain relevance and then by number of times they were reported in Medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 54.28
2 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 2.67
3 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 21.11
4 INT158 Localization of Prl 2431 0.81 378.96 952.2 1.77
5 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.10
6 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 0.42
7 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 2.68
8 INT3439 Localization of Abat 1017 0.78 112.39 727.06 5.33
9 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 20.85
10 INT292 Localization of Penk 876 0.81 88.44 669.14 15.13
11 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 1.80
12 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 15.44
13 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 2.30
14 INT797 Regulation of Penk 812 0.62 111.13 542.24 10.85
15 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 13.92
16 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 8.90
17 INT1045 Localization of LH 1211 0.81 87.04 456.25 0.49
18 INT443 Localization of POMC 1020 0.81 284.52 443.17 4.40
19 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 0.66
20 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 0.51
21 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 2.97
22 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 1.88
23 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.69
24 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 12.03
25 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 10.58
26 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 1.04
27 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 1.15
28 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 0.23
29 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 0.67
30 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 13.21
31 INT287 Localization of Cck 518 0.81 86.84 364.04 0.71
32 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 0.51
33 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 1.61
34 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 2.15
35 INT876 Localization of Gh1 843 0.80 67.75 340.82 0.57
36 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 0.73
37 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 0.64
38 INT2649 Regulation of Calca 433 0.62 146.05 330.95 2.63
39 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 0.44
40 INT162 Regulation of Prl 794 0.62 165.01 322.24 0.08
41 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 6.33
42 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 0.05
43 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 5.28
44 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 0.45
45 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 0.12
46 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 1.74
47 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 3.35
48 INT477 Localization of Avp 813 0.81 131.58 300.4 2.11
49 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 0.31
50 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 1.78
51 INT1352 Localization of Acot1 728 0.80 73.01 296.01 3.25
52 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 5.26
53 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 2.14
54 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 5.02
55 INT3579 Localization of Oxt 555 0.81 43.35 292.44 1.82
56 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 0.07
57 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 1.65
58 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 0.35
59 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 0.45
60 INT6852 Localization of TNF 883 0.81 705.95 270.84 0.90
61 INT1396 Binding of Penk 355 0.48 22.79 269.65 3.59
62 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 8.21
63 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 3.40
64 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 0.20
65 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 0.14
66 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 0.24
67 INT1893 Localization of Gh 1041 0.79 340.23 256.58 0.07
68 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 0.07
69 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 2.71
70 INT3948 Regulation of Cck 291 0.62 58.07 255.88 1.31
71 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 0.80
72 INT1005 Localization of Sst 385 0.81 26.31 244.56 0.59
73 INT738 Regulation of POMC 459 0.62 111.19 243.74 2.67
74 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 1.42
75 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 0.46
76 INT1562 Localization of Crh 499 0.81 126.74 236.68 1.28
77 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 0.90
78 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 2.73
79 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 0.23
80 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 1.54
81 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 2.87
82 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 3.22
83 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 1.00
84 INT626 Localization of CALCA 289 0.81 125.39 221.15 1.15
85 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 1.53
86 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 7.56
87 INT1308 Localization of Pomc 457 0.81 66.83 217.5 5.21
88 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 2.24
89 INT6481 Binding of TNF 624 0.48 510.2 214.82 0.24
90 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 0.46
91 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 4.01
92 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 0.38
93 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 0.55
94 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 0.09
95 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 3.01
96 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 5.67
97 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 1.17
98 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 5.21
99 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 0.82
100 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 0.48
101 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 1.86
102 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 0.63
103 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 0.16
104 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 2.43
105 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 2.91
106 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 1.53
107 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 0.13
108 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 4.13
109 INT4803 Transcription of Penk 435 0.72 59.09 182.4 6.81
110 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36 1.47
111 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 2.16
112 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 0.13
113 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 1.17
114 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 0.77
115 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 0.42
116 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1 0.53
117 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93 0.73
118 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 0.43
119 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 0.57
120 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 1.27
121 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 0.23
122 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 0.98
123 INT1114 Localization of Ins1 748 0.80 192.95 165.48 0.90
124 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 0.47
125 INT2366 Binding of Cck 192 0.48 30.64 163.46 0.60
126 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 0.13
127 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 5.08
128 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 2.11
129 INT21185 Binding of Ptprg 213 0.47 13.49 157.75 3.37
130 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 0.08
131 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 1.19
132 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 0.31
133 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.65
134 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 1.19
135 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 11.55
136 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 1.98
137 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 0.69
138 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 0.16
139 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 3.37
140 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 1.39
141 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 0.18
142 INT812 Localization of INS 1026 0.81 515.6 145.31 0.85
143 INT2379 Positive_regulation of Localization of LH 349 0.70 27.86 144.53 0.21
144 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 0.22
145 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 3.04
146 INT9660 Regulation of TNF 363 0.62 312.94 139.99 0.05
147 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 0.16
148 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 0.22
149 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 0.79
150 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 1.40
151 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 0.06
152 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 0.53
153 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 3.13
154 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 0.35
155 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 0.69
156 INT2541 Binding of Calca 200 0.48 67.14 134.62 0.17
157 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 1.12
158 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132 0.85
159 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 2.63
160 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 0.89
161 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 1.74
162 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 0.79
163 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 0.91
164 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 0.74
165 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 2.08
166 INT695 Binding of POMC 304 0.48 56.66 126.85 0.49
167 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 0.80
168 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93 1.70
169 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 0.15
170 INT416 Regulation of LH 253 0.62 31.48 125.55 0.17
171 INT5008 Localization of Calca 204 0.81 80.35 125.16 0.19
172 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 1.02
173 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 0.58
174 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 0.69
175 INT252 Localization of GH1 529 0.80 227.4 122.05 0.36
176 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 0.87
177 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 0.07
178 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 0.39
179 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 6.20
180 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 0.57
181 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73 1.17
182 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 0.47
183 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 2.12
184 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 1.61
185 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 0.05
186 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 0.28
187 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 0.07
188 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 0.47
189 INT12339 Localization of IL8 437 0.81 251.87 117.39 0.06
190 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 0.23
191 INT1438 Localization of Pomc 360 0.81 101.26 116.47 1.66
192 INT4207 Regulation of Avp 267 0.62 63.72 115.33 1.09
193 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 0.25
194 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 1.37
195 INT1793 Localization of CGA 379 0.81 67.38 114.69 0.36
196 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 2.35
197 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 0.41
198 INT90 Localization of Gast 400 0.81 137.67 113 3.24
199 INT1530 Regulation of Gh 382 0.61 115.96 112.47 0.36
200 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 0.55
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