P:Medulla

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pChart

Pain Term
Category Anatomy
Synonyms Brainstem
Pain Specific No
Documents 6149
Hot Single Events 200
Hot Interactions 189

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Medulla. They are ordered first by their pain relevance and then by number of times they were reported for Medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39 100.00
2 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34 100.00
3 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34 100.00
4 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34 100.00
5 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33 100.00
6 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33 100.00
7 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74 100.00
8 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23 100.00
9 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02 100.00
10 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95 100.00
11 INT253826 Cck Regulation of Nts 1 0.21 0.36 0.94 100.00
12 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46 100.00
13 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35 100.00
14 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35 100.00
15 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35 100.00
16 INT253835 Binding of DST and Fos 1 0.02 0 0.55 100.00
17 INT253832 Binding of Fos and Nts 1 0.14 0 0.54 100.00
18 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44 100.00
19 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82 100.00
20 INT31276 Oxt Negative_regulation of Cpe 1 0.01 0 0.31 100.00
21 INT31275 Avp Negative_regulation of Cpe 1 0.00 0 0.31 100.00
22 INT31277 Penk Negative_regulation of Cpe 1 0.12 0 0.29 100.00
23 INT30378 Binding of Sst and Penk 1 0.28 0.52 1.01 100.00
24 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67 100.00
25 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66 100.00
26 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42 100.00
27 INT146240 Binding of AP1B1 and Mrgprc 1 0.08 0.82 0.85 99.90
28 INT10552 Penk Positive_regulation of Regulation of Cebpz 1 0.44 0.25 1.03 99.82
29 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52 99.68
30 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5 99.68
31 INT354235 Aif1 Regulation of P2ry12 1 0.20 0.49 0.45 99.68
32 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15 99.68
33 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69 99.68
34 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23 99.64
35 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 0.40 0 0.2 99.56
36 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29 99.44
37 INT88445 Uncx Positive_regulation of Gene_expression of Penk 1 0.10 0 0.17 99.36
38 INT16933 Tsc22d3 Positive_regulation of Localization of Penk 2 0.24 0 0.76 99.36
39 INT37905 Cck Negative_regulation of Binding of Nts 1 0.64 0 0.61 99.28
40 INT37906 Cck Negative_regulation of Nts 1 0.64 0 0.61 99.28
41 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56 99.24
42 INT91539 Pomc Positive_regulation of Pomc Positive_regulation of P9Ehs1 1 0.03 0.84 3.13 99.24
43 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67 99.24
44 INT88447 Uncx Negative_regulation of Binding of Jun 1 0.07 0 0.22 99.14
45 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34 99.04
46 INT158399 Binding of Preb and Frg1 1 0.01 0.3 0.62 99.04
47 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93 98.84
48 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14 98.74
49 INT61510 Binding of Trh and Gm14673 1 0.01 0 0.48 98.68
50 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57 98.56
51 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53 98.52
52 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53 98.52
53 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62 98.36
54 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27 98.20
55 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11 98.16
56 INT119918 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 1.64 98.16
57 INT85791 Prlh Regulation of Localization of Prl 1 0.23 0 0.26 98.08
58 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53 98.00
59 INT35982 LH Negative_regulation of tf 1 0.03 0.18 0.77 97.96
60 INT14621 Gal Regulation of Npy 1 0.30 0 0.7 97.92
61 INT79593 Binding of Reg1 and LMTK2 1 0.00 0.32 0.53 97.84
62 INT35984 Ptger2 Positive_regulation of fut10 1 0.10 0.86 0.14 97.84
63 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27 97.84
64 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15 97.84
65 INT135498 Binding of YY1 and MRGPRX4 1 0.00 0.2 0.62 97.80
66 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03 97.80
67 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28 97.76
68 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69 97.72
69 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95 97.64
70 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8 97.56
71 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92 97.52
72 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68 97.52
73 INT66580 Binding of Ap1s1 and Rare2 1 0.00 0.07 0.76 97.52
74 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83 97.52
75 INT56181 sch Regulation of Positive_regulation of Nppa 1 0.07 0.08 0.14 97.42
76 INT36733 Positive_regulation of Prn Negative_regulation of Gene_expression of Mtap 1 0.16 0.44 0.28 97.40
77 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02 97.40
78 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4 97.40
79 INT289049 Binding of Slc38a1 and Sat2 1 0.02 0 0.05 97.36
80 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55 97.32
81 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66 97.24
82 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21 97.16
83 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1 97.04
84 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32 97.04
85 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 96.88
86 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64 96.68
87 INT105422 Fosl2 Positive_regulation of Gene_expression of Penk 1 0.31 0 0.55 96.64
88 INT5217 Binding of GRDX and Tas2r124 1 0.11 0.37 0.05 96.60
89 INT5216 Binding of GRDX and Ighg3 1 0.42 0.37 0.05 96.60
90 INT71518 Binding of INSRR and Nisch 1 0.00 0.22 0.35 96.56
91 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34 96.56
92 INT214165 Agrp Negative_regulation of Localization of Npy 1 0.23 0.06 0.1 96.56
93 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12 96.40
94 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 96.36
95 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09 96.24
96 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 0.03 0 0.44 96.24
97 INT105421 Fos Positive_regulation of Gene_expression of Penk 1 0.54 0 0.55 95.96
98 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 95.96
99 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 95.92
100 INT84085 Binding of Gucy1a2 and Nisch 1 0.00 0.22 0.35 95.72
101 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48 95.72
102 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21 95.48
103 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 95.32
104 INT144343 Binding of Npffr2 and Qrfp 1 0.37 0 0.37 95.28
105 INT144345 Binding of Qrfpr and Qrfp 1 0.40 0 0.34 95.28
106 INT144344 Binding of Npvf and Qrfp 1 0.16 0 0.34 95.28
107 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92 95.16
108 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63 95.08
109 INT83869 Oprm1 Regulation of Gene_expression of Fos 1 0.01 0 0.18 94.84
110 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05 94.68
111 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 94.24
112 INT275802 Hcrt Regulation of Rem1 1 0.20 0.95 0.17 94.20
113 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84 93.76
114 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16 93.68
115 INT46085 Binding of MET and Penk 1 0.02 0.06 0.83 93.60
116 INT46084 Binding of SELL and Penk 1 0.02 0.06 0.83 93.60
117 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1 93.32
118 INT257805 Binding of Car3 and Gopc 1 0.18 0 0.25 93.16
119 INT46076 Binding of MET and SELL 1 0.39 0.06 0.83 93.08
120 INT40854 Man2a2 Regulation of Regulation of Eef1a1 1 0.03 0 0.25 93.04
121 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38 92.88
122 INT106547 Oprm1 Regulation of Oprm1 1 0.04 0 0.23 92.72
123 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09 92.56
124 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 92.40
125 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 92.40
126 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53 90.96
127 INT214156 Pomc Negative_regulation of Gene_expression of Npy 1 0.39 0.07 0.09 90.88
128 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12 90.40
129 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64 90.32
130 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 89.68
131 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64 89.68
132 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08 89.52
133 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59 89.44
134 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59 89.44
135 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 89.24
136 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56 89.04
137 INT122832 AP1B1 Negative_regulation of Gene_expression of FLII 1 0.01 0 0.47 88.64
138 INT106871 Grip2 Regulation of Tacr3 1 0.00 0 0.32 88.56
139 INT24336 Negative_regulation of Binding of PRB1 and RTCA 1 0.00 0.1 0.45 87.80
140 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75 87.52
141 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 87.36
142 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11 87.32
143 INT340318 Gopc Regulation of Ntrk2 1 0.24 0.1 0.08 87.28
144 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02 87.20
145 INT88451 Uncx Regulation of Transcription of Penk 1 0.06 0 0.17 86.72
146 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17 86.72
147 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08 86.56
148 INT175802 Il1 Positive_regulation of Gene_expression of Fos 1 0.00 0.66 0.44 86.48
149 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15 86.04
150 INT24335 Positive_regulation of Binding of PRB1 and RTCA 1 0.00 0.09 0.44 85.92
151 INT85792 Prlh Positive_regulation of Localization of Prl 1 0.39 0 0.24 85.68
152 INT349686 Nmu Positive_regulation of Nmur1 1 0.36 0.2 0.45 85.56
153 INT24334 Binding of PRB1 and RTCA 1 0.00 0.09 0.44 85.52
154 INT287096 Binding of Bdnf and FL 1 0.16 1.15 0.6 85.52
155 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55 85.44
156 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87 85.32
157 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 85.28
158 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97 85.20
159 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 84.96
160 INT237452 Binding of STAR and CHTF8 1 0.00 0.48 0.45 84.96
161 INT151780 Calca Positive_regulation of Camkk2 1 0.01 0.48 0.61 84.76
162 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 84.64
163 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79 84.48
164 INT293121 Avp Regulation of Gene_expression of Agt 1 0.06 0.78 0.04 84.36
165 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43 83.96
166 INT353630 Binding of Psmd1 and Shbdp1 1 0.02 0 0.76 83.92
167 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44 83.64
168 INT158283 Binding of Penk and Accn4 1 0.07 0.87 1.43 83.64
169 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34 83.48
170 INT134488 Il1b Regulation of Oxt 1 0.30 0.08 0.54 82.84
171 INT104162 HTR1D Regulation of Localization of CALCA 1 0.31 0.28 0.58 82.80
172 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46 82.16
173 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75 81.96
174 INT159386 Positive_regulation of TRPV1 Positive_regulation of Localization of Calca 1 0.05 0.44 0.69 81.88
175 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 81.76
176 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94 81.44
177 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18 81.12
178 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18 81.12
179 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31 81.08
180 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 81.00
181 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 80.88
182 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18 80.76
183 INT304497 Mknk1 Positive_regulation of Nos1 1 0.19 0.53 0.3 80.72
184 INT304536 Mknk1 Positive_regulation of PRKG1 1 0.03 0.53 0.3 80.72
185 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51 80.72
186 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 80.56
187 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35 80.32
188 INT57094 Oprl1 Positive_regulation of Negative_regulation of Rtcd1 1 0.01 0.1 0.71 80.12
189 INT305509 Slc17a7 Positive_regulation of Ex 1 0.05 0.09 0.23 80.08
190 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34 80.00
191 INT261047 MZB1 Positive_regulation of Positive_regulation of CA2 1 0.02 0.09 0.3 79.28
192 INT354306 Binding of Rgs4 and Rgs1 1 0.40 0.36 0.98 79.24
193 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08 78.96
194 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 78.96
195 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11 78.80
196 INT119772 Binding of Cd53 and Gfap 1 0.04 1.01 0.81 78.76
197 INT175083 TAF6L Regulation of Gene_expression of PENK 1 0.00 0.05 0.04 78.16
198 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36 77.84
199 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 77.52
200 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 77.52

Single Events

The table below shows the top 200 pain related interactions that have been reported for Medulla. They are ordered first by their pain relevance and then by number of times they were reported in Medulla. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
2 INT292 Localization of Penk 876 0.81 88.44 669.14 100.00
3 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
4 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
5 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
6 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 100.00
7 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 100.00
8 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
9 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
10 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04 100.00
11 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 100.00
12 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
13 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 100.00
14 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 100.00
15 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 100.00
16 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 100.00
17 INT95726 Positive_regulation of Gene_expression of Naa15 1 0.45 1.43 13.33 100.00
18 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 100.00
19 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
20 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 100.00
21 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67 100.00
22 INT18755 Positive_regulation of Rvm 79 0.60 60 92.93 100.00
23 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 100.00
24 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 100.00
25 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 100.00
26 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
27 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45 100.00
28 INT6107 Localization of Npy 180 0.81 26.76 81.67 100.00
29 INT8049 Regulation of Nts 18 0.53 6.15 10.39 100.00
30 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 100.00
31 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42 100.00
32 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
33 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63 100.00
34 INT8363 Localization of Nts 135 0.81 14.29 61.71 100.00
35 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
36 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67 100.00
37 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09 100.00
38 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 100.00
39 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78 100.00
40 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
41 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93 100.00
42 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
43 INT99270 Negative_regulation of Gene_expression of Pvalb 5 0.08 5.74 3.15 100.00
44 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
45 INT88601 Regulation of Positive_regulation of P9Ehs1 10 0.15 2.6 7.36 100.00
46 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 100.00
47 INT10520 Regulation of Rvm 20 0.24 10.15 20.52 100.00
48 INT209390 Negative_regulation of Localization of Ugcg 4 0.20 3.97 1.11 100.00
49 INT6073 Negative_regulation of Localization of Penk 63 0.59 8.67 53.95 100.00
50 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 100.00
51 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 100.00
52 INT128415 Positive_regulation of Agrp 36 0.64 11.87 3.91 100.00
53 INT127203 Positive_regulation of Mcf2l 14 0.43 9.84 7.03 100.00
54 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 100.00
55 INT127202 Negative_regulation of Mcf2l 8 0.50 6.7 4.15 100.00
56 INT193832 Localization of Ps 19 0.13 6.96 8.04 100.00
57 INT57125 Gene_expression of AP1B1 8 0.18 3.8 4.91 100.00
58 INT8047 Positive_regulation of Nts 20 0.67 7.96 10.35 100.00
59 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41 100.00
60 INT2699 Binding of Cpe 40 0.48 7.07 33.64 100.00
61 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
62 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 100.00
63 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 100.00
64 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 100.00
65 INT102076 Regulation of DST 15 0.22 10 3.5 100.00
66 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 100.00
67 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 100.00
68 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 100.00
69 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 100.00
70 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37 100.00
71 INT22003 Negative_regulation of Cpe 25 0.58 6.23 12.94 100.00
72 INT85616 Negative_regulation of Positive_regulation of P9Ehs1 8 0.37 4.17 8.11 100.00
73 INT13572 Localization of Helt 31 0.36 5.85 13.41 100.00
74 INT19199 Negative_regulation of Rvm 16 0.37 10.07 21.73 100.00
75 INT28971 Positive_regulation of Gene_expression of Dbh 4 0.47 0.58 2.39 100.00
76 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7 100.00
77 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38 100.00
78 INT131497 Positive_regulation of Gene_expression of Cybb 4 0.01 2.09 1.3 100.00
79 INT8050 Positive_regulation of Gene_expression of Nts 10 0.66 2.31 4.69 100.00
80 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 100.00
81 INT9157 Negative_regulation of Negative_regulation of Penk 13 0.43 2.3 9.54 100.00
82 INT16879 Binding of Crh 72 0.48 21.65 28.43 100.00
83 INT209387 Negative_regulation of Ugcg 9 0.25 7.61 0.9 100.00
84 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 100.00
85 INT174281 Positive_regulation of Positive_regulation of Agrp 4 0.41 1.71 0.91 100.00
86 INT184677 Negative_regulation of Spaca4 2 0.02 3.19 0.91 100.00
87 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98 100.00
88 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 100.00
89 INT102485 Negative_regulation of Gene_expression of Rvm 2 0.36 1.45 1.38 100.00
90 INT17379 Positive_regulation of Prlh 6 0.64 0.58 3.68 100.00
91 INT249305 Negative_regulation of Preb 7 0.39 0.62 1.12 100.00
92 INT171820 Localization of Fig4 144 0.65 27.38 20.88 100.00
93 INT340203 Regulation of Smyd5 1 0.07 1.5 1.34 100.00
94 INT25607 Binding of Il1 82 0.47 64.4 23.9 100.00
95 INT82854 Gene_expression of MRGPRX1 61 0.75 10.14 10.65 100.00
96 INT13083 Regulation of Tal2 7 0.23 1.73 4.71 100.00
97 INT55859 Binding of Dll1 6 0.35 0 7.64 100.00
98 INT85788 Negative_regulation of Prlh 5 0.54 0.95 1.09 100.00
99 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07 100.00
100 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65 100.00
101 INT214120 Regulation of Positive_regulation of Nts 1 0.06 0.31 0.87 100.00
102 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
103 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
104 INT14548 Localization of Tac1 13 0.78 1.43 7.48 100.00
105 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 100.00
106 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 100.00
107 INT8056 Regulation of Positive_regulation of Penk 34 0.59 4.71 17.66 100.00
108 INT8781 Regulation of Prlh 6 0.45 0.67 3.58 100.00
109 INT44745 Localization of Nrm 5 0.65 2.04 4.92 100.00
110 INT115416 Regulation of Gene_expression of Syt12 1 0.04 0 0.69 100.00
111 INT115417 Gene_expression of Syt12 1 0.10 0 0.68 100.00
112 INT18371 Regulation of Positive_regulation of Npy 8 0.60 2.49 4.38 100.00
113 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 100.00
114 INT63840 Positive_regulation of Positive_regulation of Gabrg1 9 0.49 0.9 4.11 100.00
115 INT87388 Negative_regulation of Positive_regulation of CHAT 1 0.42 0.41 0.34 100.00
116 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24 100.00
117 INT59307 Negative_regulation of Binding of SUPT7L 2 0.57 0.51 1.01 100.00
118 INT1849 Binding of SUPT7L 14 0.47 0.95 5.44 100.00
119 INT50812 Regulation of Positive_regulation of Dbh 2 0.45 1.04 1 100.00
120 INT90903 Positive_regulation of Positive_regulation of Oprk1 13 0.47 3.49 11.18 100.00
121 INT43212 Regulation of Gene_expression of Adra2a 4 0.45 0.24 2.48 100.00
122 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67 100.00
123 INT62987 Positive_regulation of Cat3 1 0.03 0 0.55 100.00
124 INT8391 Positive_regulation of Gene_expression of Nts 23 0.67 5.05 14.59 100.00
125 INT114273 Negative_regulation of Gene_expression of Nts 3 0.24 0.81 1.44 100.00
126 INT27918 Positive_regulation of Klk1c7 6 0.36 2.89 2.84 100.00
127 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16 100.00
128 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63 100.00
129 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69 100.00
130 INT237456 Gene_expression of MESP1 1 0.03 1.33 1.12 100.00
131 INT13650 Positive_regulation of Gene_expression of Adra2a 6 0.50 0.69 4.94 100.00
132 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81 100.00
133 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95 100.00
134 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 100.00
135 INT251226 Negative_regulation of Negative_regulation of Preb 1 0.32 0.05 0.16 100.00
136 INT135511 Positive_regulation of Positive_regulation of MRGPRX4 1 0.16 0.09 0.78 100.00
137 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53 100.00
138 INT53236 Positive_regulation of Binding of Il1 5 0.40 3.84 1.41 100.00
139 INT85790 Positive_regulation of Transcription of Prlh 1 0.43 0 0.25 100.00
140 INT85785 Negative_regulation of Transcription of Prlh 1 0.40 0 0.25 100.00
141 INT57124 Positive_regulation of AP1B1 4 0.19 0.94 1.74 100.00
142 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93 100.00
143 INT41092 Binding of Nil 2 0.06 1.43 1.04 100.00
144 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 100.00
145 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58 100.00
146 INT135866 Positive_regulation of Positive_regulation of Chrne 1 0.12 0 2.43 100.00
147 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18 100.00
148 INT233003 Negative_regulation of Gene_expression of KRT17 1 0.25 2.13 0.1 100.00
149 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 100.00
150 INT92716 Negative_regulation of PAG1 6 0.51 5.82 6.32 100.00
151 INT355657 Negative_regulation of Transcription of Agtr1a 1 0.38 1.17 0.13 100.00
152 INT22017 Negative_regulation of Nts 11 0.43 1.89 5.64 100.00
153 INT13590 Negative_regulation of Localization of Nts 8 0.42 1.36 4.59 100.00
154 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65 100.00
155 INT67982 Positive_regulation of Positive_regulation of OPRD1 3 0.04 0.33 2.02 100.00
156 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02 100.00
157 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8 100.00
158 INT62986 Positive_regulation of Cdx1 2 0.03 0.16 0.3 100.00
159 INT79347 Regulation of Gene_expression of Sert1 9 0.54 2.57 3.58 100.00
160 INT345989 Regulation of Scamp3 1 0.20 0.24 0.46 100.00
161 INT107657 Positive_regulation of Positive_regulation of Grm5 6 0.69 1.83 8.92 100.00
162 INT31451 Negative_regulation of Gene_expression of Adra2a 4 0.43 1.03 2.72 100.00
163 INT101476 Binding of P2rx6 4 0.24 1.04 1.78 100.00
164 INT73427 Localization of P2rx7 24 0.79 8.65 9.87 100.00
165 INT1473 Localization of Gcg 95 0.80 17.35 30.31 100.00
166 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32 100.00
167 INT51912 Positive_regulation of Transcription of Nts 4 0.45 1.42 1.48 100.00
168 INT42959 Negative_regulation of Vom2r2 3 0.06 0.56 1.43 100.00
169 INT10554 Regulation of Regulation of GPER 3 0.01 0.45 0.76 100.00
170 INT103300 Negative_regulation of Gene_expression of CRTAC1 3 0.44 2.87 0.7 100.00
171 INT157066 Regulation of Gene_expression of Cpb2 1 0.22 0.47 0.64 100.00
172 INT157065 Gene_expression of Cpu3 1 0.02 0.46 0.64 100.00
173 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.98
174 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.98
175 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 99.98
176 INT47764 Binding of Jun 106 0.48 22.62 31.39 99.98
177 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 99.98
178 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 99.98
179 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.98
180 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 99.98
181 INT1158 Regulation of Agt 106 0.61 29.4 30.29 99.98
182 INT13739 Positive_regulation of Positive_regulation of Avp 18 0.70 4.78 8.2 99.98
183 INT154007 Gene_expression of da 46 0.56 15.28 28.22 99.98
184 INT97523 Phosphorylation of NOS1 3 0.46 0.59 2.58 99.98
185 INT147138 Positive_regulation of Phosphorylation of NOS1 1 0.12 0.45 0.8 99.98
186 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 99.96
187 INT14453 Localization of Mme 44 0.80 2.46 14.75 99.96
188 INT4958 Gene_expression of Pcyt1b 18 0.65 3.4 5.66 99.96
189 INT170557 Gene_expression of Lepr 16 0.67 17.26 2.78 99.96
190 INT1353 Negative_regulation of Localization of Acot1 153 0.53 15.05 75.17 99.96
191 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 99.96
192 INT122933 Negative_regulation of Regulation of Calb1 1 0.02 1.12 1.27 99.96
193 INT69075 Regulation of Calb1 6 0.02 2.43 2.31 99.96
194 INT30317 Regulation of TH 14 0.43 7.27 5.38 99.96
195 INT126291 Positive_regulation of Rgs4 3 0.67 1.3 3.19 99.96
196 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 99.96
197 INT85789 Gene_expression of Prlh 10 0.78 4.5 5.47 99.96
198 INT85787 Transcription of Prlh 4 0.53 1.77 2.7 99.96
199 INT44059 Positive_regulation of Vom1r68 4 0.06 0.75 2.09 99.96
200 INT122934 Negative_regulation of Regulation of TH 1 0.03 0.56 0.63 99.96
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