P:Norepinephrine uptake inhibitor

Pain Term Category Drug class Synonyms Norepinephrine Uptake Inhibitors Pain Specific No Documents 30 Hot Single Events 33 Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Norepinephrine uptake inhibitor. They are ordered first by their pain relevance and then by number of times they were reported for Norepinephrine uptake inhibitor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT127437	deltaFosB Negative_regulation of Vta1	1	0.01	0.09	1.06	95.56

Single Events

The table below shows the top 200 pain related interactions that have been reported for Norepinephrine uptake inhibitor. They are ordered first by their pain relevance and then by number of times they were reported in Norepinephrine uptake inhibitor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT6824	Regulation of Gene_expression of Pdyn	114	0.62	9.48	66.73	100.00
2	INT5596	Negative_regulation of Gene_expression of Pdyn	41	0.59	5.34	24.36	99.98
3	INT5597	Gene_expression of Pdyn	433	0.78	62.97	235.47	99.70
4	INT49850	Negative_regulation of PDE4A	105	0.58	76.91	26.59	99.66
5	INT27170	Gene_expression of Maoa	13	0.67	3.88	7.5	99.66
6	INT13415	Positive_regulation of Hpse	58	0.70	24.9	25.53	98.48
7	INT31774	Positive_regulation of Vta1	67	0.44	14.52	71.79	98.44
8	INT53384	Positive_regulation of FosB	41	0.69	8.43	28.91	98.00
9	INT69621	Positive_regulation of Positive_regulation of Hpse	7	0.42	4.1	2.85	96.04
10	INT5598	Negative_regulation of Pdyn	95	0.59	14.4	55.43	95.60
11	INT70572	Gene_expression of Fst	33	0.78	5.22	8.24	95.00
12	INT33094	Regulation of Localization of Ca2	28	0.38	8.65	9.96	94.80
13	INT53385	Positive_regulation of Gene_expression of FosB	26	0.70	9.18	26.33	94.12
14	INT6228	Localization of Htr1a	14	0.78	0.46	6.2	93.28
15	INT50587	Regulation of Localization of Htr1a	1	0.44	0	0.52	93.28
16	INT21527	Gene_expression of FosB	47	0.78	11.2	34.39	93.20
17	INT1437	Negative_regulation of Pomc	132	0.59	35.22	60.97	93.08
18	INT5593	Positive_regulation of Gene_expression of Pdyn	114	0.70	29.1	74.46	92.76
19	INT4822	Localization of Ca2	417	0.80	99.57	96.45	92.08
20	INT6762	Binding of Srms	56	0.31	6.62	30.27	91.24
21	INT1316	Positive_regulation of Acot1	129	0.60	18.86	56.13	91.24
22	INT940	Negative_regulation of Ptgs1	219	0.59	104.34	95.97	90.12
23	INT112986	Positive_regulation of S100b	19	0.70	17.61	6.86	88.80
24	INT20060	Protein_catabolism of Acot1	6	0.56	0.22	2.45	88.48
25	INT22721	Regulation of Protein_catabolism of Acot1	2	0.23	0.17	0.53	88.48
26	INT605	Regulation of Acot1	61	0.62	10.7	26.34	88.08
27	INT24420	Transcription of Pomc	13	0.69	3.32	4.54	86.76
28	INT112988	Positive_regulation of Transcription of S100b	2	0.47	1.62	1.36	85.56
29	INT5595	Positive_regulation of Pdyn	223	0.70	48.37	130.14	85.12
30	INT10120	Negative_regulation of Positive_regulation of Pdyn	14	0.58	6.05	10.19	85.12
31	INT112987	Transcription of S100b	2	0.53	1.61	1.35	84.76
32	INT84965	Gene_expression of MAOA	15	0.75	6.9	6.06	80.08
33	INT244283	Negative_regulation of Gene_expression of MAOA	2	0.27	1.7	2.5	80.08
34	INT3188	Regulation of Localization of Acot1	84	0.59	8.94	38.56	79.96
35	INT29322	Negative_regulation of Srms	5	0.37	0.31	3.37	78.92
36	INT2640	Gene_expression of Pomc	424	0.78	120.72	155.37	78.80
37	INT1353	Negative_regulation of Localization of Acot1	153	0.53	15.05	75.17	78.08
38	INT1352	Localization of Acot1	728	0.80	73.01	296.01	77.36
39	INT40034	Localization of Maoa	7	0.80	2.17	3.69	76.64
40	INT2416	Negative_regulation of MAOA	92	0.59	42.24	36.5	75.36
41	INT5594	Regulation of Pdyn	137	0.62	27.04	86.63	75.00
42	INT1023	Negative_regulation of Pxk	13	0.59	0.76	2.7	73.68
43	INT25965	Gene_expression of Pxk	9	0.78	2	0.78	73.68
44	INT59095	Regulation of Regulation of Srms	1	0.23	0	0.41	73.44
45	INT29853	Regulation of Srms	3	0.53	0.09	1.31	72.96
46	INT50585	Positive_regulation of Line	1	0.40	0	1.02	71.68
47	INT195085	Gene_expression of S100b	12	0.56	12.26	2.33	71.56
48	INT1438	Localization of Pomc	360	0.81	101.26	116.47	71.36
49	INT15347	Positive_regulation of Localization of Pomc	81	0.70	28.1	31.01	71.36
50	INT439	Localization of Gnrh1	976	0.81	100.96	363.25	70.88
51	INT4289	Positive_regulation of Localization of Gnrh1	202	0.70	12.3	84.01	70.88
52	INT50586	Regulation of Line	1	0.23	0	1.03	67.68
53	INT6176	Positive_regulation of Htr1a	117	0.67	28.23	66.17	57.68
54	INT108433	Negative_regulation of Mat1a	16	0.57	14.15	2.82	57.20
55	INT54052	Gene_expression of App	33	0.78	25.08	14.7	47.48
56	INT39846	Gene_expression of Olr1746	12	0.75	0.61	3.22	25.00
57	INT127436	Positive_regulation of Tfap2d	1	0.08	0	0.33	25.00
58	INT158	Localization of Prl	2431	0.81	378.96	952.2	5.00
59	INT155	Positive_regulation of Prl	1233	0.70	317.93	457.82	5.00
60	INT16260	Gene_expression of Bdnf	671	0.78	283.44	339.1	5.00
61	INT16259	Positive_regulation of Bdnf	336	0.70	183.48	209.82	5.00
62	INT16253	Positive_regulation of Gene_expression of Bdnf	196	0.70	92.67	113.01	5.00
63	INT49651	Gene_expression of Creb1	276	0.78	114.77	111.96	5.00
64	INT1169	Negative_regulation of Bche	322	0.59	149.22	61.27	5.00
65	INT8713	Regulation of Tac1	56	0.60	25.29	45.94	5.00
66	INT88617	Positive_regulation of Gene_expression of Creb1	90	0.69	51.69	44.29	5.00
67	INT96557	Binding of Bdnf	46	0.47	21.74	24.26	5.00
68	INT9231	Binding of Htr3a	27	0.47	7.29	13.04	5.00
69	INT56031	Positive_regulation of App	25	0.69	13.46	7.37	5.00
70	INT50105	Localization of CTSB	29	0.78	10.98	5.21	5.00
71	INT78116	Positive_regulation of Gene_expression of App	12	0.70	10.78	4.52	5.00
72	INT52402	Negative_regulation of Htr2c	7	0.42	1.46	4.21	5.00
73	INT6063	Positive_regulation of Bche	17	0.66	6.07	3.08	5.00
74	INT54055	Regulation of Gene_expression of App	7	0.62	4.04	2.93	5.00
75	INT229111	Localization of SLC6A3	5	0.68	1.12	2.48	5.00
76	INT81154	Gene_expression of HCRT	10	0.75	5.32	2.22	5.00
77	INT39008	Localization of App	13	0.77	9.07	2.05	5.00
78	INT50106	Positive_regulation of Localization of CTSB	9	0.33	3.15	1.69	5.00
79	INT148883	Gene_expression of HCRTR1	8	0.36	24.82	1.35	5.00
80	INT244284	Binding of SLC18A2	1	0.23	1.87	1.34	5.00
81	INT103488	Positive_regulation of Localization of App	5	0.50	3.05	1.28	5.00
82	INT99281	Negative_regulation of HCRT	3	0.57	2.26	0.71	5.00
83	INT264605	Negative_regulation of Binding of Htr3a	1	0.01	1.12	0.64	5.00
84	INT148884	Negative_regulation of HCRTR1	7	0.23	7.23	0.53	5.00