P:Pain threshold

Pain Term Category Other Synonyms None Pain Specific Yes Documents 2582 Hot Single Events 200 Hot Interactions 21

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pain threshold. They are ordered first by their pain relevance and then by number of times they were reported for Pain threshold. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT138961	Dbi Positive_regulation of Chkb	1	0.00	3.05	3.99	100.00
2	INT138959	Dbi Positive_regulation of Penk	1	0.01	3.05	3.99	100.00
3	INT138962	Dbi Positive_regulation of Pomc	1	0.00	1.53	2	100.00
4	INT138960	Dbi Positive_regulation of Avp	1	0.02	1.53	2	100.00
5	INT138958	Dbi Positive_regulation of Positive_regulation of Avp	1	0.02	1.53	2	100.00
6	INT14910	Binding of GPR182 and SIT1	1	0.02	1.87	1.73	97.60
7	INT56308	POMC Negative_regulation of Gene_expression of Il2	1	0.01	0.1	0.67	97.44
8	INT140015	Avp Positive_regulation of Localization of Penk	3	0.63	3.48	6.63	97.12
9	INT262377	Binding of Comt and Fmod	1	0.06	1.47	1.29	95.20
10	INT40209	TNS3 Regulation of POMC	1	0.16	0.27	1.47	94.16
11	INT142490	Avp Regulation of Oxt	1	0.09	0.74	1.4	93.24
12	INT341897	Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt	1	0.32	0.42	1.07	92.88
13	INT89943	Binding of Oprm1 and Il2	1	0.03	0.53	1.28	91.00
14	INT46645	Binding of Gabrg1 and Chrm5	1	0.29	0.09	1	90.48
15	INT340115	Comt Regulation of Localization of Dusp1	1	0.12	0.83	0.83	86.24
16	INT340114	Comt Regulation of Localization of Pain1	1	0.02	0.83	0.83	86.24
17	INT42262	Pomc Positive_regulation of POMC	1	0.21	0.35	0.24	85.48
18	INT284858	Binding of Gabbr1 and Pdzd2	1	0.03	0.24	0.15	83.44
19	INT284856	Regulation of Binding of Gabbr1 and Pdzd2	1	0.04	0.24	0.15	83.44
20	INT82023	Binding of Ntrk1 and Ngf	5	0.53	3.48	3.92	83.04
21	INT51705	Binding of Penk and Naga	1	0.19	0.08	0.69	80.36
22	INT54601	Binding of Mtor and Ache	1	0.20	0.8	1.58	76.20
23	INT34837	Maob Regulation of Negative_regulation of Mme	1	0.48	0.15	0.92	76.12
24	INT130469	Tubgcp2 Negative_regulation of Naalad2	1	0.05	0.44	0.5	76.00
25	INT224822	Binding of ENOX1 and GOPC	1	0.00	0.34	0.34	72.68
26	INT284857	S100a10 Positive_regulation of Gene_expression of Nav1	1	0.16	0.3	0.17	71.08
27	INT145260	Binding of CLU and App	1	0.00	0.74	0.46	65.20
28	INT187845	Binding of ESR1 and Esr2	1	0.01	0.17	0.06	61.40
29	INT226306	CHPT1 Positive_regulation of Localization of DBP	1	0.26	0.65	0.64	55.44
30	INT226308	CHPT1 Positive_regulation of Localization of SHBG	1	0.09	0.65	0.64	55.44
31	INT284860	Binding of Pdzd2 and Nav1	9	0.29	2.33	2.34	44.40
32	INT287746	Anxa1 Positive_regulation of Gene_expression of Lpar1	1	0.07	1.72	2.46	40.52
33	INT309708	Palm Regulation of Positive_regulation of Penk	1	0.19	1.25	0.91	35.96
34	INT340117	Binding of Bdnf and Pain1	1	0.01	2.48	2.55	32.96
35	INT208621	Binding of Prph and Nmbr	1	0.05	0.43	1.12	32.00
36	INT342688	Binding of Cap1 and Nav1	1	0.00	0.19	0.14	24.16
37	INT284853	Binding of S100a10 and Pdzd2	1	0.21	0.08	0.09	23.12
38	INT284855	Binding of S100a10 and Nav1	4	0.21	0.99	0.88	16.72
39	INT158770	Binding of Trpv1 and Trpa1	5	0.34	2.07	3.5	9.44
40	INT84921	Binding of NGF and NTRK1	13	0.50	6.39	6.1	5.00
41	INT15842	Crh Positive_regulation of Localization of Pomc	15	0.73	5	5.05	5.00
42	INT127128	Binding of CNR1 and CNR2	8	0.39	3.98	3.97	5.00
43	INT15984	Binding of Avp and Oxt	11	0.32	1.33	3.64	5.00
44	INT340118	Binding of Sugt1 and Pain1	1	0.00	3.53	3.44	5.00
45	INT220062	Binding of NGF and TNFRSF1B	1	0.10	2.21	2.81	5.00
46	INT220061	Binding of TRPV1 and TRPA1	1	0.15	1.7	2.69	5.00
47	INT29446	Crh Positive_regulation of Localization of POMC	8	0.38	1.87	2.58	5.00
48	INT103548	Binding of TRPV1 and TRPV3	3	0.37	1.82	2.28	5.00
49	INT331105	Vmn1r71 Negative_regulation of Mc1r	1	0.04	0.64	2.07	5.00
50	INT264953	Binding of POMC and TLR4	1	0.03	0.89	1.96	5.00
51	INT264947	Binding of POMC and TLR2	1	0.03	0.89	1.95	5.00
52	INT97208	Binding of Gabrg1 and Gabbr1	2	0.07	0.31	1.94	5.00
53	INT351281	AP1M2 Regulation of NCOR2	1	0.00	0.85	1.9	5.00
54	INT264950	Binding of FPR1 and BOC	1	0.11	0.67	1.55	5.00
55	INT220058	NGF Positive_regulation of Gene_expression of BDNF	1	0.12	1.31	1.48	5.00
56	INT220059	NGF Positive_regulation of Positive_regulation of BDNF	1	0.11	1.31	1.48	5.00
57	INT220060	Negative_regulation of Binding of NGF and NTRK1	1	0.08	1.11	1.39	5.00
58	INT279165	Calca Regulation of Gene_expression of Fdft1	1	0.02	0.41	1.37	5.00
59	INT228681	Fkbp4 Negative_regulation of Trib3	1	0.00	0.57	1.2	5.00
60	INT228680	Fkbp1a Negative_regulation of Trib3	1	0.01	0.56	1.18	5.00
61	INT287749	Dmbx1 Positive_regulation of Gene_expression of Lpar1	1	0.41	0.82	1.16	5.00
62	INT296950	Tacr1 Negative_regulation of Gene_expression of Cck	1	0.30	0.94	1.11	5.00
63	INT331108	Mc1r Positive_regulation of Mc4r	1	0.44	1.05	1.06	5.00
64	INT331107	Vmn1r71 Positive_regulation of Mc1r	1	0.05	0.5	1.05	5.00
65	INT331109	Tpnr1 Regulation of Gene_expression of Calca	1	0.06	0.97	0.94	5.00
66	INT318461	Nnat Positive_regulation of Mapk14	1	0.05	0.97	0.92	5.00
67	INT250976	Binding of FMOD and IL8	1	0.08	1.26	0.91	5.00
68	INT279166	Binding of Cyp3a23/3a1 and Nr3c2	1	0.00	0.61	0.9	5.00
69	INT264944	Binding of POMC and BOC	1	0.07	0.44	0.89	5.00
70	INT318462	Nnat Positive_regulation of Nfkb1	1	0.46	0.9	0.88	5.00
71	INT340113	Comt Regulation of Bdnf	1	0.21	0.74	0.82	5.00
72	INT220056	Binding of NTF3 and NTRK1	1	0.07	1.12	0.78	5.00
73	INT220063	Binding of NTF3 and NTRK2	1	0.09	1.13	0.78	5.00
74	INT305034	Adcy8 Regulation of Localization of Adcy1	1	0.35	1.51	0.77	5.00
75	INT305033	Adcy1 Regulation of Localization of Adcy8	1	0.35	1.51	0.77	5.00
76	INT220057	Binding of NTS and TNFRSF1B	1	0.08	1.23	0.76	5.00
77	INT307754	Ik Negative_regulation of Trpa1	1	0.07	0.08	0.71	5.00
78	INT340116	Dusp1 Regulation of Transcription of Oprm1	1	0.12	0.71	0.69	5.00
79	INT207411	Sst Negative_regulation of Gene_expression of Tacr1	1	0.05	0.76	0.69	5.00
80	INT224823	CTBS Regulation of SALL1	1	0.14	0.53	0.66	5.00
81	INT207410	Ptger2 Regulation of Gene_expression of Tacr1	1	0.02	0.69	0.65	5.00
82	INT264943	Negative_regulation of Binding of FPR1 and BOC	1	0.13	0.22	0.64	5.00
83	INT264946	Binding of FPR1 and GOPC	1	0.08	0.21	0.64	5.00
84	INT264952	Binding of GOPC and BOC	1	0.05	0.22	0.64	5.00
85	INT324065	Ptger2 Positive_regulation of Prkaca	2	0.24	0.63	0.61	5.00
86	INT287753	Lpar3 Positive_regulation of Gene_expression of Lpar1	1	0.46	0.39	0.58	5.00
87	INT287744	Lpar3 Positive_regulation of Positive_regulation of Lpar1	1	0.46	0.39	0.58	5.00
88	INT287752	Dmbx1 Positive_regulation of Positive_regulation of Lpar1	1	0.41	0.39	0.58	5.00
89	INT342689	Ptger4 Positive_regulation of Prkaca	1	0.03	0.24	0.51	5.00
90	INT27730	Binding of ALB and Shbg	2	0.01	0.44	0.5	5.00
91	INT264948	BOC Negative_regulation of FPR1	1	0.13	0.18	0.48	5.00
92	INT264949	BOC Negative_regulation of Localization of FPR1	1	0.13	0.18	0.48	5.00
93	INT264975	BOC Negative_regulation of Localization of Oprd1	1	0.01	0.17	0.48	5.00
94	INT321045	Anpep Positive_regulation of Protein_catabolism of Ptpn6	1	0.01	0.22	0.48	5.00
95	INT342693	Binding of Prkaca and Gopc	1	0.01	0.23	0.48	5.00
96	INT264945	GOPC Positive_regulation of Positive_regulation of FPR1	1	0.10	0.2	0.44	5.00
97	INT189197	RASGRP1 Positive_regulation of JUN	1	0.07	1.26	0.43	5.00
98	INT321046	Anpep Regulation of Negative_regulation of Hps4	1	0.02	0.25	0.43	5.00
99	INT321047	Anpep Regulation of Negative_regulation of Ptpn6	1	0.01	0.25	0.43	5.00
100	INT309199	Abat Positive_regulation of Adarb1	1	0.00	0	0.42	5.00
101	INT250975	Binding of FMOD and CSAD	1	0.01	0.86	0.41	5.00
102	INT287751	Rbm39 Positive_regulation of Positive_regulation of Lpar1	1	0.01	0.48	0.39	5.00
103	INT287754	Lpar2 Positive_regulation of Gene_expression of Lpar1	1	0.44	0.48	0.39	5.00
104	INT287745	Rbm39 Positive_regulation of Gene_expression of Lpar1	1	0.01	0.48	0.39	5.00
105	INT287740	Lpar3 Regulation of Gene_expression of Lpar1	1	0.60	0.53	0.39	5.00
106	INT287743	Lpar2 Positive_regulation of Positive_regulation of Lpar1	1	0.44	0.48	0.39	5.00
107	INT208623	Nmbr Positive_regulation of Prph	1	0.04	0.15	0.36	5.00
108	INT228922	Binding of Prf1 and RCT	1	0.08	0.36	0.36	5.00
109	INT342687	Pdzd2 Regulation of Gene_expression of Nav1	1	0.19	0.3	0.35	5.00
110	INT342691	Pdzd2 Regulation of Nav1	1	0.19	0.48	0.34	5.00
111	INT207408	Il6 Positive_regulation of Gene_expression of Tacr1	1	0.08	0.56	0.33	5.00
112	INT342882	Positive_regulation of Ephb1 Regulation of Gene_expression of Pdyn	1	0.01	0.36	0.33	5.00
113	INT207409	Ptger2 Positive_regulation of Gene_expression of Tacr1	1	0.04	0.56	0.32	5.00
114	INT216043	Binding of Rtn4r and Lingo1	1	0.15	0.82	0.3	5.00
115	INT287747	Anxa1 Positive_regulation of Lpar1	1	0.04	0	0.29	5.00
116	INT287755	Positive_regulation of Binding of Lpar3 and Dmbx1	1	0.50	0	0.29	5.00
117	INT287748	Positive_regulation of Anxa1 Positive_regulation of Lpar1	1	0.04	0	0.29	5.00
118	INT189200	Binding of CA2 and ITPR3	3	0.03	1.9	0.27	5.00
119	INT216040	Binding of Comt and Prodh	1	0.30	1.71	0.26	5.00
120	INT287742	Binding of Lpar3 and Dmbx1	1	0.37	0	0.26	5.00
121	INT256656	Binding of EP300 and HHIP	1	0.22	0	0.24	5.00
122	INT189199	JUN Positive_regulation of KRT16	1	0.31	0.58	0.22	5.00
123	INT189196	RASGRP1 Positive_regulation of SP1	1	0.05	0.63	0.21	5.00
124	INT216041	Binding of Tnfrsf1b and Rtn4r	1	0.10	0.75	0.2	5.00
125	INT195423	COMT Negative_regulation of GBE1	1	0.00	0.22	0.19	5.00
126	INT341896	Oxt Regulation of Localization of POMC	1	0.07	0.91	0.19	5.00
127	INT195424	SNRNP70 Negative_regulation of GBE1	1	0.00	0.22	0.19	5.00
128	INT341895	Oxt Positive_regulation of Localization of POMC	1	0.08	0.49	0.15	5.00
129	INT216042	Binding of Rtn4r and Gtf3a	1	0.01	0.41	0.15	5.00
130	INT284861	S100a10 Positive_regulation of Localization of Nav1	1	0.17	0.07	0.14	5.00
131	INT216039	Binding of Prodh and Zdhhc8	1	0.30	0.85	0.13	5.00
132	INT307529	Binding of IK and TRNAC1	1	0.00	0.07	0.12	5.00
133	INT284854	Pdzd2 Positive_regulation of Gene_expression of Nav1	1	0.42	0	0.11	5.00
134	INT341879	Oxt Negative_regulation of Positive_regulation of Hpse	1	0.01	0.83	0.11	5.00
135	INT342692	Binding of Gopc and Nav1	1	0.02	0.15	0.1	5.00
136	INT341880	Oxt Positive_regulation of Ca2	1	0.09	0	0.1	5.00
137	INT342694	Binding of Pdzd2 and Gopc	1	0.03	0.15	0.1	5.00
138	INT332806	Positive_regulation of Ccl20 Regulation of Map3k8	1	0.05	0.05	0.1	5.00
139	INT342690	Binding of Sft2d3 and Pdzd2	1	0.00	0.15	0.09	5.00
140	INT341877	Oxtr Regulation of Ca2	1	0.08	0	0.09	5.00
141	INT189195	Binding of C4A and C4B	1	0.14	2.45	0.09	5.00
142	INT224985	Binding of Ube3a and Snord116	1	0.34	0.45	0.08	5.00
143	INT189202	Binding of C4B and HAS2	1	0.02	1.25	0.05	5.00
144	INT216044	Positive_regulation of Binding of Tnfrsf1b and Rtn4r	1	0.14	0.34	0.05	5.00
145	INT341882	Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2	1	0.02	0.11	0.05	5.00
146	INT224988	Binding of Snord116 and Snurf	1	0.15	0.22	0.04	5.00
147	INT224991	Snord116 Positive_regulation of SNORD108	1	0.37	0.61	0.04	5.00
148	INT228679	Binding of Rps6kb1 and Fig4	1	0.08	0.08	0.04	5.00
149	INT189198	Binding of C4A and SERPINF1	1	0.12	1.17	0.04	5.00
150	INT224986	Binding of Snrpn and Snord116	1	0.30	0.21	0.04	5.00
151	INT224990	Snord116 Positive_regulation of SNORD107	1	0.38	0.62	0.04	5.00
152	INT224987	Snord116 Positive_regulation of Snord64	1	0.55	0.62	0.04	5.00
153	INT200063	Binding of MAGED1 and Ngfr	1	0.44	0.45	0	5.00
154	INT200060	Binding of Nuc and Ndn	1	0.10	0.29	0	5.00
155	INT200058	Binding of Ndn and Bbs4	1	0.30	0.29	0	5.00
156	INT308927	Gtf2i Positive_regulation of Gene_expression of Parp1	1	0.24	0	0	5.00
157	INT189203	CHGB Regulation of CA2	1	0.04	0.95	0	5.00
158	INT200062	Binding of Ngfr and Bbs4	1	0.30	0.3	0	5.00
159	INT226307	DBP Positive_regulation of Binding of CHPT1	1	0.26	0	0	5.00
160	INT200053	Binding of Nuc and Ngfr	1	0.10	0.3	0	5.00
161	INT189201	CHGB Regulation of Localization of CA2	1	0.04	0.95	0	5.00
162	INT200057	Binding of Ndn and Ngfr	1	0.43	1.96	0	5.00
163	INT200064	Binding of MAGED1 and Mageh1	1	0.30	0.23	0	5.00
164	INT200061	Binding of Ngfr and Fez1	1	0.31	0.3	0	5.00
165	INT226305	SHBG Positive_regulation of Binding of CHPT1	1	0.09	0	0	5.00
166	INT200056	Binding of Ndn and Fez1	1	0.31	0.28	0	5.00
167	INT200065	Binding of MAGED1 and Ntf3	1	0.32	0.23	0	5.00
168	INT200059	Gtf3a Positive_regulation of Ndn	1	0.06	0.89	0	5.00
169	INT200054	Binding of Ntf3 and Mageh1	1	0.24	0.22	0	5.00
170	INT200055	Binding of Ngfr and Mageh1	1	0.33	0.45	0	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Pain threshold. They are ordered first by their pain relevance and then by number of times they were reported in Pain threshold. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT4726	Negative_regulation of PPT1	15	0.57	10.09	14.17	100.00
2	INT11764	Positive_regulation of ENG	78	0.61	27.65	33.69	100.00
3	INT4729	Positive_regulation of PPT1	19	0.67	7.11	17.83	100.00
4	INT99088	Gene_expression of HPT	5	0.59	9.1	6.72	100.00
5	INT113961	Regulation of PPT1	6	0.26	3.87	6.09	100.00
6	INT169435	Gene_expression of CHPT1	17	0.61	10.04	7.37	100.00
7	INT90655	Negative_regulation of Hpt	3	0.37	3.24	1.72	100.00
8	INT17458	Negative_regulation of Gene_expression of FOS	98	0.57	36.77	55.69	100.00
9	INT5300	Regulation of Insr	54	0.60	11.33	29.26	100.00
10	INT159044	Gene_expression of Hpt	2	0.57	2.01	1.82	100.00
11	INT215977	Localization of HPT	2	0.36	3.43	2.19	100.00
12	INT87623	Gene_expression of PPT1	9	0.75	5.32	7.65	100.00
13	INT14575	Positive_regulation of Ppt1	60	0.70	9.97	27.4	100.00
14	INT189003	Localization of CHPT1	8	0.64	4.75	1.82	100.00
15	INT63444	Regulation of Gene_expression of Abat	26	0.51	14.65	26.29	100.00
16	INT248	Positive_regulation of Localization of GH1	137	0.69	49.25	32.92	100.00
17	INT462	Regulation of Pomc	157	0.62	41.67	67.27	100.00
18	INT64503	Negative_regulation of PDSS1	3	0.38	1.39	1.47	100.00
19	INT34977	Gene_expression of Hmga2	11	0.76	12.39	3.07	100.00
20	INT37950	Regulation of PDSS1	3	0.44	1.24	0.91	100.00
21	INT140822	Localization of PPT1	2	0.57	1.1	1.94	100.00
22	INT1437	Negative_regulation of Pomc	132	0.59	35.22	60.97	100.00
23	INT5774	Regulation of Ppt1	22	0.60	4.97	7.1	100.00
24	INT2910	Regulation of Abat	169	0.62	36.95	153.53	100.00
25	INT32135	Positive_regulation of Positive_regulation of ENG	2	0.02	0.98	1.99	100.00
26	INT15307	Regulation of Mtor	27	0.48	4.7	9.34	100.00
27	INT8794	Negative_regulation of Ppt1	35	0.57	6.44	14.52	100.00
28	INT15262	Negative_regulation of Positive_regulation of Avp	22	0.58	3.28	10.81	100.00
29	INT7340	Regulation of Grin1	87	0.62	30.37	57.93	100.00
30	INT74237	Positive_regulation of Ppt1	3	0.49	2.92	2.32	100.00
31	INT984	Positive_regulation of Localization of GHRH	58	0.70	12.66	16.51	100.00
32	INT75698	Negative_regulation of Negative_regulation of Ppt1	1	0.42	1.01	1.11	100.00
33	INT17701	Gene_expression of PTHLH	103	0.78	64.23	8.85	100.00
34	INT75699	Negative_regulation of Ppt1	2	0.58	1.07	1.08	100.00
35	INT48979	Regulation of Gene_expression of FOS	52	0.61	14.4	25.95	100.00
36	INT10500	Regulation of Cenpf	3	0.39	0.27	5.26	100.00
37	INT137961	Localization of Ppt1	1	0.64	2.89	3.09	100.00
38	INT74709	Positive_regulation of Agxt	1	0.12	0.62	0.29	100.00
39	INT34978	Negative_regulation of Gene_expression of Hmga2	2	0.42	1.53	0.95	100.00
40	INT8590	Regulation of Positive_regulation of Tacr1	4	0.62	1.43	2.73	100.00
41	INT238713	Positive_regulation of Gene_expression of CHPT1	3	0.43	2.7	1.97	100.00
42	INT158278	Positive_regulation of Myst2	2	0.41	0.89	1.02	100.00
43	INT19575	Negative_regulation of Positive_regulation of Abat	14	0.43	2.07	11.05	100.00
44	INT1644	Regulation of FSHR	77	0.55	15.62	21.49	100.00
45	INT1648	Regulation of LHB	21	0.61	3.32	9.6	100.00
46	INT250	Regulation of GHRH	65	0.61	17.46	23.19	100.00
47	INT253	Regulation of PRL	184	0.62	47.27	65.79	100.00
48	INT163365	Positive_regulation of TNS3	2	0.41	0.96	4.18	100.00
49	INT23226	Positive_regulation of tf	23	0.43	15.55	14.37	100.00
50	INT38467	Negative_regulation of Dpa	3	0.33	1.42	5.95	99.98
51	INT147527	Regulation of Gene_expression of PPT1	1	0.44	1.17	1.69	99.98
52	INT159397	Regulation of Regulation of PPT1	1	0.26	0.54	0.76	99.98
53	INT69761	Gene_expression of Jag2	5	0.67	6.17	0.53	99.98
54	INT6665	Gene_expression of FOS	520	0.77	165.31	217.66	99.96
55	INT203	Positive_regulation of Pomc	257	0.70	90.56	92.84	99.96
56	INT161812	Positive_regulation of PER1	17	0.56	5.64	2.93	99.96
57	INT103261	Positive_regulation of Nav1	68	0.70	24.25	39.27	99.96
58	INT238706	Localization of CDT1	1	0.17	1.16	0.93	99.92
59	INT1652	Regulation of Pomc	387	0.62	61.01	186.51	99.92
60	INT7674	Regulation of ENG	42	0.30	11.41	14.44	99.92
61	INT6116	Regulation of Gene_expression of Oprd1	69	0.62	16.43	54	99.92
62	INT9987	Gene_expression of Abat	296	0.78	95.46	226.34	99.90
63	INT17459	Positive_regulation of Gene_expression of FOS	182	0.67	53.45	96.38	99.90
64	INT7675	Gene_expression of ENG	146	0.77	45.35	34.6	99.88
65	INT12228	Positive_regulation of Gene_expression of Abat	44	0.65	17.51	40.55	99.88
66	INT608	Negative_regulation of KNG1	98	0.43	72.36	31.23	99.84
67	INT5533	Binding of Oxt	43	0.48	8.69	18.35	99.84
68	INT7362	Gene_expression of Sst	185	0.78	41.73	111.37	99.84
69	INT14098	Regulation of Gene_expression of Sst	13	0.44	4.01	12.92	99.84
70	INT62452	Regulation of Il2	14	0.61	12.11	7.64	99.84
71	INT3217	Regulation of Ins1	154	0.62	87.11	27.29	99.84
72	INT82434	Positive_regulation of LEP	117	0.70	95.45	20.22	99.84
73	INT17886	Negative_regulation of Il1	95	0.57	70.91	31.25	99.84
74	INT4842	Regulation of Npff	13	0.54	4.59	13.62	99.84
75	INT49509	Negative_regulation of Ptger2	53	0.42	24.87	11.66	99.84
76	INT47390	Negative_regulation of Paf	18	0.58	14.81	9.66	99.84
77	INT21350	Negative_regulation of Ltb4r1	11	0.33	6.77	2.88	99.84
78	INT738	Regulation of POMC	459	0.62	111.19	243.74	99.80
79	INT21941	Regulation of CALR	7	0.53	3.88	1.96	99.80
80	INT915	Positive_regulation of PRL	342	0.70	141.96	104.31	99.76
81	INT238710	Localization of MREG	1	0.05	1.16	0.93	99.72
82	INT5034	Negative_regulation of Insr	100	0.55	28.08	54.5	99.66
83	INT66040	Positive_regulation of Bdnf	114	0.69	67.67	51.81	99.66
84	INT157776	Localization of TGM1	2	0.39	2.52	0.74	99.64
85	INT157778	Localization of CYP4F22	2	0.73	0.35	1.15	99.64
86	INT4824	Positive_regulation of Tacr1	169	0.70	66.1	123.46	99.64
87	INT2451	Positive_regulation of Avp	355	0.70	102.66	147.69	99.62
88	INT1273	Gene_expression of Avp	356	0.78	90.56	138.7	99.62
89	INT886	Gene_expression of Pomc	676	0.78	129.87	295.98	99.62
90	INT2651	Positive_regulation of Pomc	403	0.70	95.72	206.24	99.62
91	INT5941	Gene_expression of Oxt	164	0.76	22.63	65.47	99.62
92	INT20260	Positive_regulation of Chkb	41	0.64	21.48	18.53	99.62
93	INT5989	Positive_regulation of Dbi	79	0.49	24.38	32.56	99.62
94	INT7470	Positive_regulation of Gene_expression of Avp	37	0.70	19.55	19.96	99.62
95	INT21550	Gene_expression of Olr1737	4	0.03	1.58	3.78	99.62
96	INT20264	Gene_expression of Chkb	29	0.46	13.14	13.65	99.62
97	INT728	Positive_regulation of Penk	1068	0.70	186.9	636.87	99.62
98	INT20345	Gene_expression of Dbi	136	0.78	56.41	46.2	99.62
99	INT796	Gene_expression of Penk	1902	0.78	275.47	1057.59	99.62
100	INT7469	Positive_regulation of Gene_expression of Oxt	18	0.59	4.7	14.36	99.62
101	INT5539	Negative_regulation of Mme	75	0.59	28.91	41.84	99.60
102	INT15055	Regulation of Negative_regulation of Mme	2	0.42	0.24	0.67	99.60
103	INT739	Negative_regulation of POMC	358	0.59	102.28	166.77	99.54
104	INT3118	Negative_regulation of Positive_regulation of POMC	33	0.59	9.42	18.07	99.54
105	INT18778	Gene_expression of Ugt1a2	17	0.35	9.91	6.87	99.54
106	INT5200	Gene_expression of Fos	3083	0.78	894.43	1639.02	99.52
107	INT249	Localization of GHRH	215	0.80	78.02	51.87	99.52
108	INT252	Localization of GH1	529	0.80	227.4	122.05	99.52
109	INT1004	Regulation of Sst	140	0.62	18.52	94.84	99.52
110	INT17546	Negative_regulation of Ngf	135	0.59	60.28	77.19	99.52
111	INT255	Regulation of Localization of GH1	89	0.62	18.71	35.3	99.52
112	INT254	Regulation of Localization of GHRH	30	0.60	5.17	11.46	99.52
113	INT12001	Regulation of Ngf	97	0.62	54.64	76.25	99.52
114	INT16303	Negative_regulation of Localization of GH1	89	0.59	37.31	22.15	99.50
115	INT304003	Positive_regulation of Gene_expression of S1pr4	1	0.14	0.43	1.48	99.50
116	INT23179	Positive_regulation of Lgmn	2	0.40	0.41	1.01	99.48
117	INT121967	Regulation of RAC1	9	0.45	6.14	3.41	99.48
118	INT4941	Positive_regulation of Oprd1	345	0.70	74.26	304.41	99.46
119	INT16868	Gene_expression of Il6	807	0.78	499.48	256.57	99.44
120	INT65551	Transcription of Htr3a	5	0.69	1.52	3.74	99.44
121	INT6174	Regulation of Gene_expression of POMC	49	0.61	9.75	27.69	99.40
122	INT29290	Regulation of Gene_expression of PRL	13	0.49	6.46	5.23	99.40
123	INT5979	Gene_expression of Oprd1	428	0.78	75.64	320.32	99.38
124	INT767	Localization of Gnrhr	565	0.80	106.68	214.57	99.36
125	INT41660	Regulation of IL31RA	2	0.45	1.46	1.81	99.36
126	INT238709	Binding of PCBD1	1	0.34	2.37	1.41	99.32
127	INT720	Positive_regulation of POMC	807	0.70	237.37	353.83	99.30
128	INT894	Binding of Avp	84	0.48	29.16	29.63	99.30
129	INT1463	Binding of Pomc	129	0.48	15.89	56.27	99.30
130	INT1396	Binding of Penk	355	0.48	22.79	269.65	99.30
131	INT1197	Negative_regulation of Localization of POMC	109	0.59	28.29	48.02	99.30
132	INT5610	Positive_regulation of Insr	140	0.69	37.26	86.24	99.24
133	INT5940	Negative_regulation of Avp	236	0.59	67.86	101.2	99.24
134	INT7696	Negative_regulation of Fdft1	9	0.21	2.8	5.64	99.24
135	INT136678	Positive_regulation of Gene_expression of Shc1	4	0.50	2.93	1.42	99.24
136	INT2085	Positive_regulation of LH	441	0.70	60.15	191.02	99.20
137	INT443	Localization of POMC	1020	0.81	284.52	443.17	99.16
138	INT425	Localization of PRL	455	0.81	189.64	144.8	99.16
139	INT165258	Binding of BC013712	1	0.06	0.85	1.02	99.16
140	INT47955	Localization of Eid2b	1	0.33	0.35	3.12	99.16
141	INT101542	Positive_regulation of RRAD	6	0.44	5.34	0.42	99.12
142	INT102442	Gene_expression of S1pr4	6	0.29	2.17	3.51	99.10
143	INT7716	Positive_regulation of Positive_regulation of Adra2a	9	0.68	0.8	4.69	99.10
144	INT6128	Positive_regulation of Localization of POMC	256	0.70	68.77	121.64	99.08
145	INT610	Regulation of PENK	47	0.62	14.17	31.55	99.08
146	INT158	Localization of Prl	2431	0.81	378.96	952.2	99.04
147	INT83492	Positive_regulation of Htr5b	4	0.47	1.84	4.58	99.04
148	INT83491	Positive_regulation of Negative_regulation of Htr5b	1	0.34	0.33	1.01	99.04
149	INT4207	Regulation of Avp	267	0.62	63.72	115.33	99.00
150	INT3830	Positive_regulation of FCGR3B	27	0.67	15.18	10.49	98.92
151	INT16122	Localization of Cenpf	4	0.57	0.61	4.93	98.92
152	INT3840	Negative_regulation of FCGR3B	18	0.59	8.9	5.97	98.92
153	INT18570	Gene_expression of HERPUD1	3	0.57	0.45	2.15	98.92
154	INT13400	Negative_regulation of Enpep	30	0.50	4.23	15.86	98.88
155	INT44053	Regulation of Negative_regulation of Enpep	1	0.17	0.24	0.37	98.88
156	INT7717	Positive_regulation of Adra2a	62	0.70	17.68	27.32	98.86
157	INT467	Gene_expression of POMC	1048	0.78	332.8	394.16	98.80
158	INT157634	Regulation of Nkr-p1c	2	0.37	1.65	1.7	98.80
159	INT528	Gene_expression of Prl	693	0.78	217.18	192.2	98.80
160	INT1512	Binding of Prl	73	0.48	26.22	20.63	98.80
161	INT2909	Positive_regulation of Abat	334	0.70	62.1	256.43	98.74
162	INT136681	Gene_expression of Shc1	13	0.77	9.67	2.52	98.72
163	INT1642	Negative_regulation of Localization of PLOD1	40	0.58	10.67	17.95	98.70
164	INT339	Regulation of Trh	156	0.62	39.27	83.55	98.68
165	INT82828	Positive_regulation of COMP	45	0.61	35.12	6.2	98.68
166	INT35712	Regulation of Sdcbp	19	0.23	5.3	6.58	98.68
167	INT159091	Positive_regulation of Regulation of Sdcbp	1	0.40	0.16	1.5	98.68
168	INT15517	Regulation of Paf	5	0.45	6.74	3.06	98.64
169	INT6849	Localization of IL1B	229	0.81	112.56	69.63	98.58
170	INT2649	Regulation of Calca	433	0.62	146.05	330.95	98.56
171	INT98205	Gene_expression of PCBD1	10	0.61	14.78	7.27	98.52
172	INT50972	Negative_regulation of Ntrk1	39	0.51	32.22	17.29	98.52
173	INT4841	Localization of Npff	26	0.80	4.36	19.91	98.48
174	INT14769	Positive_regulation of Positive_regulation of Insr	10	0.43	2.66	5.55	98.48
175	INT102009	Negative_regulation of Binding of Gnai1	1	0.39	0.1	0.59	98.48
176	INT54190	Binding of Gnai1	2	0.34	0.28	1.47	98.48
177	INT9230	Gene_expression of Htr3a	43	0.78	10.54	18.81	98.46
178	INT1728	Negative_regulation of Cndp2	36	0.57	3.76	25.39	98.44
179	INT3076	Regulation of KNG1	52	0.60	20.39	27.89	98.44
180	INT920	Localization of PLOD1	223	0.81	42.25	78.7	98.42
181	INT3838	Regulation of FCGR3B	16	0.60	6.67	5.53	98.40
182	INT986	Negative_regulation of Localization of GHRH	16	0.58	8.57	3.16	98.40
183	INT3834	Regulation of su	3	0.18	1.85	1.16	98.40
184	INT30961	Binding of HTR2A	33	0.47	11.44	12.86	98.40
185	INT16540	Gene_expression of Il1r2	14	0.61	3.29	5.2	98.40
186	INT35711	Positive_regulation of Sdcbp	110	0.60	50.45	22.11	98.40
187	INT1579	Gene_expression of PRL	279	0.78	119.2	55.41	98.36
188	INT2365	Positive_regulation of Cck	354	0.70	87.8	277.41	98.32
189	INT95207	Negative_regulation of Pde5a	46	0.58	32.01	10.14	98.32
190	INT8357	Gene_expression of KNG1	153	0.75	77.26	68.66	98.32
191	INT287	Localization of Cck	518	0.81	86.84	364.04	98.32
192	INT2862	Positive_regulation of Localization of Cck	108	0.70	20.75	94.25	98.32
193	INT10166	Localization of Tnf	237	0.81	153.95	88.64	98.32
194	INT10138	Negative_regulation of Gene_expression of KNG1	13	0.57	9.57	4.9	98.32
195	INT14768	Negative_regulation of Positive_regulation of Insr	16	0.56	5.51	13.59	98.30
196	INT5513	Negative_regulation of Pomc	295	0.59	60.9	158.63	98.28
197	INT480	Negative_regulation of Localization of Avp	151	0.59	27.64	63.72	98.16
198	INT83493	Negative_regulation of Htr5b	3	0.34	1.22	3.12	98.14
199	INT12345	Gene_expression of Il2	142	0.78	59.17	51.21	98.12
200	INT2323	Gene_expression of Trh	146	0.78	29.92	49.5	98.12