P:bile

Pain Term Category Molecule Synonyms Cholycystokinin, Pancreozymin Pain Specific No Documents 4506 Hot Single Events 200 Hot Interactions 160

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for bile. They are ordered first by their pain relevance and then by number of times they were reported for bile. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT2881	SST Negative_regulation of Positive_regulation of CCK	1	0.32	0.1	0.84	100.00
2	INT2880	SST Negative_regulation of CCK	1	0.32	0.1	0.84	100.00
3	INT262220	Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2	1	0.14	0.25	0.44	100.00
4	INT262153	Binding of Clta and Nr1i2	1	0.05	0.65	0.38	100.00
5	INT335028	Fgf15 Positive_regulation of Fgfr4	1	0.40	0.31	0.25	100.00
6	INT99676	Cck Positive_regulation of Insrr	1	0.11	0.07	0.33	100.00
7	INT262144	Nr1h4 Positive_regulation of Positive_regulation of Nr1i2	1	0.19	0.19	0.27	100.00
8	INT262202	Nr1i2 Regulation of Abcc2	1	0.19	0.12	0.25	100.00
9	INT262200	Nr1i2 Regulation of Sult2a1	1	0.31	0.12	0.25	100.00
10	INT262180	Nr1h4 Regulation of Sult2a1	1	0.11	0.11	0.25	100.00
11	INT262152	Nr1h4 Regulation of Abcc2	1	0.07	0.12	0.25	100.00
12	INT63196	INS Positive_regulation of IL2	1	0.10	0.3	0.23	100.00
13	INT63203	INS Positive_regulation of ESR1	1	0.09	0.3	0.23	100.00
14	INT63195	INS Positive_regulation of CD8A	1	0.19	0.3	0.23	100.00
15	INT63193	POMC Positive_regulation of PGR	1	0.17	0.3	0.23	100.00
16	INT63199	INS Positive_regulation of PGR	1	0.11	0.3	0.23	100.00
17	INT63202	POMC Positive_regulation of CD8A	1	0.30	0.3	0.23	100.00
18	INT63198	POMC Positive_regulation of ESR1	1	0.14	0.3	0.23	100.00
19	INT63197	POMC Positive_regulation of IL2	1	0.16	0.3	0.23	100.00
20	INT35966	SCT Regulation of Localization of LIPF	1	0.32	0.24	0.22	100.00
21	INT35967	SCT Positive_regulation of Localization of LIPF	1	0.33	0.24	0.22	100.00
22	INT153154	OPN1MW Regulation of PTPRF	1	0.03	0.51	0.14	100.00
23	INT83370	Binding of HRAS and TP53	1	0.30	0.59	0.11	100.00
24	INT229288	Binding of FXR1 and BAS	1	0.01	0.59	0.05	100.00
25	INT229275	Binding of FXR1 and BAS Negative_regulation of FXR1	1	0.00	0.59	0.05	100.00
26	INT229331	Binding of FXR1 and Nr1h2	1	0.02	0.61	0.05	100.00
27	INT186191	Binding of SCARB1 and TBP	1	0.03	2.57	0.24	99.92
28	INT327112	HCCS Positive_regulation of Gene_expression of SLCO1B3	1	0.03	0.65	0.19	99.92
29	INT262159	Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1	1	0.09	0.14	0.23	99.88
30	INT173121	PPARA Negative_regulation of Gene_expression of CYP7A1	1	0.18	0.48	0.12	99.88
31	INT144110	PRSS1 Positive_regulation of Gene_expression of IL8	1	0.21	1.38	0.48	99.78
32	INT262211	Nr1h4 Negative_regulation of Gene_expression of Cyp7a1	1	0.09	0.14	0.23	99.68
33	INT344707	Scarb1 Positive_regulation of Positive_regulation of Hdl1	1	0.14	0.88	0.14	99.52
34	INT344710	Lipc Positive_regulation of Positive_regulation of Hdl1	1	0.04	0.87	0.14	99.52
35	INT321293	Binding of Nr1h4 and Nr0b2	1	0.18	0.31	0.43	99.40
36	INT182124	Binding of IRF6 and TLR4	14	0.10	16.11	4.65	99.36
37	INT343834	Binding of CD14 and IRF6	1	0.02	2.08	0.9	99.36
38	INT343844	Binding of IRF6 and LY96	1	0.01	1.03	0.4	99.36
39	INT35862	PRSS1 Regulation of Localization of GBE1	1	0.00	0.35	0.59	99.28
40	INT35859	PRSS1 Regulation of Regulation of CCK	1	0.13	0.18	0.3	99.28
41	INT35863	PRSS1 Regulation of Positive_regulation of CCK	1	0.22	0.18	0.3	99.28
42	INT35858	PRSS1 Regulation of Positive_regulation of SCT	1	0.17	0.18	0.3	99.28
43	INT63192	PTH Positive_regulation of ESR1	1	0.20	0.29	0.22	99.28
44	INT63201	PTH Positive_regulation of CD8A	1	0.45	0.29	0.22	99.28
45	INT63200	PTH Positive_regulation of IL2	1	0.24	0.29	0.22	99.28
46	INT63194	PTH Positive_regulation of PGR	1	0.25	0.29	0.22	99.28
47	INT229290	BAS Negative_regulation of LDLR	1	0.03	0.83	0.13	99.20
48	INT262165	Nr0b2 Negative_regulation of Nr5a2	1	0.02	0.5	0.92	99.02
49	INT121364	ZNF398 Negative_regulation of Transcription of MIF	1	0.00	0.9	0.43	99.00
50	INT121365	ZNF398 Negative_regulation of Gene_expression of MIF	1	0.00	0.73	0.38	98.96
51	INT344704	Positive_regulation of Ppara Positive_regulation of Binding of Hdl1	1	0.13	0.83	0.28	98.90
52	INT344715	Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp	1	0.02	0.83	0.28	98.90
53	INT262208	Clta Positive_regulation of Nr1i2	1	0.09	0.59	0.29	98.58
54	INT348372	Binding of PROC and Stard10	1	0.01	0.41	0.2	98.32
55	INT262186	Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1	1	0.12	0.28	0.4	97.92
56	INT335134	PPARA Negative_regulation of Cyp1a1	1	0.47	0	0.28	97.92
57	INT339695	Binding of CYP3A4 and TRO	1	0.06	0.57	0.05	97.92
58	INT182125	Binding of CD14 and TLR4	7	0.25	3.78	1.03	97.76
59	INT329799	Binding of CD14 and LY96	2	0.04	1.02	0.39	97.76
60	INT262155	Nr5a2 Positive_regulation of Cyp7a1	1	0.07	0.24	0.45	97.36
61	INT186188	Binding of SCARB1 and PDZK1	1	0.53	0.54	0.05	97.32
62	INT173126	CYP8B1 Positive_regulation of PPARA	1	0.25	0.39	0.1	97.20
63	INT333394	CFD Negative_regulation of Gene_expression of Cat	1	0.03	0.79	0.22	97.20
64	INT333397	CFD Negative_regulation of Gene_expression of Nos2	1	0.04	0.8	0.22	97.20
65	INT262182	Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1	1	0.23	0.36	0.36	97.16
66	INT48341	Negative_regulation of Pde8a Regulation of Ahsg	1	0.22	0	0.9	97.16
67	INT262205	Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11	1	0.33	0.11	0.38	97.08
68	INT48342	Pde8a Regulation of Ahsg	1	0.24	0	0.9	96.64
69	INT229289	FGF19 Negative_regulation of CYP7A1	1	0.26	0.32	0.16	96.56
70	INT232914	Binding of KRT2 and KRT7	1	0.15	0.63	0.05	96.56
71	INT232907	Binding of KRT7 and KRT8	1	0.09	0.63	0.05	96.56
72	INT321300	Ins1 Negative_regulation of Pck1	1	0.09	0.52	0.59	96.52
73	INT321285	Ins1 Negative_regulation of G6pc	1	0.07	0.52	0.59	96.52
74	INT321292	Fig4 Negative_regulation of Pck1	1	0.10	0.33	0.39	96.52
75	INT321301	Fig4 Negative_regulation of G6pc	1	0.07	0.33	0.39	96.52
76	INT239355	Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP	1	0.17	3.75	0.14	96.44
77	INT141242	Binding of SYP and DNLZ	1	0.29	1.74	0.41	95.84
78	INT239323	Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1	1	0.00	3.71	0.14	95.56
79	INT278610	CDCA2 Negative_regulation of NR1H4	1	0.01	0.62	0.13	95.44
80	INT44977	Negative_regulation of Mthfs Negative_regulation of Gfra1	1	0.00	0.2	0.15	95.40
81	INT335015	Fgf15 Negative_regulation of Gene_expression of Cyp7a1	1	0.57	0.2	0.24	95.16
82	INT232917	Binding of KRT8 and KRT19	2	0.16	1.04	0.08	94.76
83	INT232916	Binding of KRT2 and KRT19	1	0.21	0.62	0.05	94.76
84	INT262179	Nr1i2 Regulation of Gene_expression of Nr0b2	1	0.09	0.07	0.24	94.64
85	INT335130	PPARA Positive_regulation of Cyp8b1	1	0.37	0	0.27	94.24
86	INT170835	Cftr Positive_regulation of Cftr Negative_regulation of Slc10a2	1	0.55	0.31	0.56	94.04
87	INT170833	Cftr Negative_regulation of Slc10a2	1	0.47	0.31	0.56	94.04
88	INT275850	Binding of NDUFAB1 and SNCA	1	0.00	3.78	3.16	93.68
89	INT229285	BAS Negative_regulation of FGF19	1	0.07	0.33	0.05	93.24
90	INT321366	Gsk3b Regulation of Gene_expression of CYP8B1	1	0.01	0.21	0.33	92.88
91	INT262167	Binding of Nr1i2 and Nr0b2	1	0.15	0.11	0.25	92.64
92	INT173200	PPA1 Positive_regulation of Myc	1	0.08	0.5	0.12	92.48
93	INT173122	PPA1 Positive_regulation of HRAS	1	0.08	0.5	0.12	92.48
94	INT173125	PPA1 Positive_regulation of JUN	1	0.06	0.5	0.12	92.48
95	INT335046	PPARA Positive_regulation of Gene_expression of ABCA1	1	0.33	0.25	0.18	92.36
96	INT4381	RIPK2 Positive_regulation of Localization of INS	1	0.13	0.53	0.34	92.24
97	INT229329	NR0B2 Negative_regulation of Nr1h2	1	0.03	0.58	0.05	92.16
98	INT262227	Nr1h4 Regulation of Transcription of CYP3A4	1	0.08	0.12	0.26	91.80
99	INT335049	PPARA Negative_regulation of Gene_expression of CYP7B1	1	0.27	0	0.26	91.80
100	INT343916	Hspa1a Positive_regulation of Gene_expression of TNF	1	0.16	1.17	0.41	91.80
101	INT343919	Hspa1a Positive_regulation of Gene_expression of IL6	1	0.02	1.17	0.4	91.80
102	INT343907	Hspa1a Positive_regulation of Gene_expression of Cxcl2	1	0.01	1.17	0.4	91.80
103	INT89225	Calca Regulation of Localization of Cck	1	0.44	0	0.48	91.60
104	INT89224	Calca Regulation of Cck	1	0.44	0	0.48	91.60
105	INT335025	Gm7647 Positive_regulation of Gene_expression of Fgf21	1	0.01	0.29	0.21	91.56
106	INT344714	Nr1h4 Negative_regulation of Gene_expression of Lipg	1	0.02	0.77	0.23	91.56
107	INT283520	Binding of DLAT and Pain1	1	0.27	0.65	0.22	91.36
108	INT229332	BAS Negative_regulation of Pck1	1	0.01	0.2	0.28	90.88
109	INT186185	Binding of SCARB1 and SCARB2	1	0.22	0.58	0.05	90.56
110	INT186192	Binding of SCARB2 and TBP	1	0.02	0.58	0.05	90.56
111	INT229292	FXR1 Regulation of Gene_expression of FGF19	1	0.08	1.14	0.37	90.32
112	INT343918	IgG Positive_regulation of Phosphorylation of MAPK1	1	0.01	3.57	0.91	90.28
113	INT343909	IgG Positive_regulation of Gene_expression of TLR4	1	0.04	3.49	0.91	90.28
114	INT348363	PCTP Positive_regulation of PROC	1	0.01	0.41	0.2	89.92
115	INT229293	Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2	1	0.02	0.59	0.04	89.36
116	INT278611	Binding of CASR and SULT2A1	1	0.03	0	0.07	89.20
117	INT278602	Binding of SULT2A1 and NR1I3	1	0.04	0	0.07	89.20
118	INT278600	Binding of CASR and SULT2A1 Positive_regulation of SULT2A1	1	0.03	0	0.07	89.20
119	INT170834	Cftr Regulation of Slc10a2	1	0.58	0.37	0.22	88.88
120	INT262189	Binding of Nr1i2 and Nr1h4	1	0.14	0.18	0.36	88.80
121	INT121378	Fancl Positive_regulation of MIF	1	0.01	0.92	0.42	88.64
122	INT335027	Binding of Vdr and Fgf23	1	0.24	0.34	0.29	88.12
123	INT231561	Binding of CYP2A and PPIG	1	0.06	0	0.09	87.92
124	INT262210	Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11	1	0.31	0.4	0.2	87.76
125	INT281193	Nr1i2 Positive_regulation of Positive_regulation of Casr	1	0.27	0	0.13	86.80
126	INT262197	Nr1i2 Positive_regulation of Insig1	2	0.23	0	0.12	86.80
127	INT281194	Casr Positive_regulation of Positive_regulation of Nr1i2	1	0.27	0	0.13	86.72
128	INT142437	Urb1 Negative_regulation of Faah	3	0.41	2.12	1.66	86.56
129	INT281192	Casr Positive_regulation of Insig1	1	0.23	0	0.12	86.16
130	INT262218	Nr1h4 Regulation of Nr1i2	1	0.10	0.15	0.34	85.96
131	INT46285	SCT Positive_regulation of PRSS1	1	0.16	0.1	0.19	85.96
132	INT46284	CCK Positive_regulation of CTRC	1	0.09	0.1	0.19	85.96
133	INT46286	SCT Positive_regulation of CTRC	1	0.24	0.1	0.19	85.96
134	INT46283	CCK Positive_regulation of PRSS1	1	0.06	0.1	0.19	85.96
135	INT278684	Binding of NR1I3 and Rxra	1	0.00	0	0.07	85.92
136	INT278685	Binding of CASR and Rxra	1	0.00	0	0.07	85.92
137	INT110653	Lep Regulation of Localization of Cck	1	0.06	0.22	0.22	85.16
138	INT335018	Vdr Positive_regulation of Gene_expression of Fgf23	1	0.44	0.36	0.17	85.04
139	INT321290	Positive_regulation of Nr1h4 Positive_regulation of Nr0b2	1	0.20	0.2	0.18	84.80
140	INT339707	TRO Positive_regulation of CYP3A4	1	0.12	0.97	0.04	84.16
141	INT339903	Binding of SCN5A and ZGLP1	1	0.01	0.18	0.22	84.08
142	INT343851	Positive_regulation of Binding of IRF6 and TLR4	1	0.07	1.96	0.66	84.00
143	INT176020	IL8 Negative_regulation of Phosphorylation of HMGCR	1	0.00	0.1	0.11	83.96
144	INT121382	Casr Positive_regulation of Abcc3	1	0.32	0.25	0.19	83.08
145	INT121381	Casr Positive_regulation of Positive_regulation of Abcc3	1	0.30	0.25	0.19	83.08
146	INT121380	Casr Positive_regulation of Positive_regulation of Cyp3a11	1	0.15	0.25	0.18	83.08
147	INT329850	APOA5 Negative_regulation of Transcription of APOC3	1	0.24	0.85	0.15	82.80
148	INT321286	Ins1 Negative_regulation of Transcription of G6pc	1	0.05	0.19	0.2	82.72
149	INT170832	Cftr Regulation of Scnn1a	2	0.16	1.2	0.67	82.72
150	INT287794	Binding of IGHG3 and AIP	1	0.05	2.8	0.24	82.28
151	INT173120	Binding of PPARA and NR1H4	8	0.09	2.79	0.23	82.16
152	INT229330	Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK	1	0.01	0.62	0.07	81.88
153	INT229333	Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4	1	0.02	0.62	0.07	81.88
154	INT100823	Cyp2e1 Positive_regulation of Ros1	1	0.35	1.22	0.22	81.64
155	INT335026	Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1	1	0.45	0.2	0.13	81.12
156	INT335024	Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1	1	0.39	0.19	0.13	81.12
157	INT186187	LDLR Regulation of Gene_expression of SCARB1	1	0.17	1.71	0.04	81.12
158	INT335021	Fgf23 Negative_regulation of Gene_expression of Cyp27b1	1	0.53	1.49	0.21	80.72
159	INT335020	Fgf23 Positive_regulation of Gene_expression of Cyp24a1	1	0.62	0.82	0.18	80.72
160	INT327188	Gnat3 Regulation of PAEP	1	0.25	1.38	0.11	80.12
161	INT331600	Il18 Regulation of IFN1@	1	0.00	1.05	0.16	79.00
162	INT186183	Binding of SCARB2 and SASH3	1	0.00	0.49	0.04	78.84
163	INT331601	Il10 Regulation of IFN1@	1	0.00	1.05	0.16	78.60
164	INT321294	Ins1 Positive_regulation of Trh	1	0.00	0.08	0.04	78.16
165	INT173129	PTGS2 Regulation of IER3	1	0.01	0.36	0.12	77.56
166	INT173119	PPA1 Regulation of IER3	1	0.00	0.36	0.12	77.56
167	INT339901	Binding of INS and SCN5A	1	0.01	0.18	0.2	77.20
168	INT335017	Fgf23 Positive_regulation of Fgfr1	1	0.23	0.59	0.04	76.32
169	INT146721	Nppc Positive_regulation of Positive_regulation of Oprl1	1	0.16	0.34	0.07	76.00
170	INT146722	Cnp Positive_regulation of Positive_regulation of Oprl1	1	0.17	0.34	0.07	76.00
171	INT343569	Negative_regulation of Synm Positive_regulation of Gpt	1	0.01	0.96	0.29	75.76
172	INT316072	Binding of Cd3e and Ncam1	1	0.01	0.4	0.18	75.76
173	INT316074	Binding of Cd19 and Cd3e	1	0.02	0.39	0.17	75.76
174	INT4382	RIPK2 Regulation of INS	1	0.12	0.58	0.36	75.68
175	INT120866	Binding of UGT2B4 and UGT2B7	1	0.39	0	0.11	75.56
176	INT240962	Positive_regulation of Ffar1 Positive_regulation of Localization of Ins1	1	0.10	0.09	0.09	75.44
177	INT321299	Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Nr0b2	1	0.02	0.31	0.1	75.00
178	INT153785	AHR Regulation of UGT1A3	1	0.69	0.07	0.14	75.00
179	INT70495	CALCA Positive_regulation of CALCB	2	0.40	0	1.08	75.00
180	INT68272	Binding of Oprd1 and G2e3	1	0.00	0.11	1.93	74.72
181	INT68273	G2e3 Negative_regulation of Binding of Oprd1 and G2e3	1	0.00	0.11	1.93	74.72
182	INT107001	F2 Positive_regulation of PAR1	4	0.05	2.15	0.92	74.36
183	INT106992	F2 Positive_regulation of PARD3	3	0.05	1.83	0.72	74.12
184	INT177350	Binding of CEL and PLA2G2A	1	0.06	0.08	0.04	73.80
185	INT106999	F2 Positive_regulation of PAR4	3	0.06	1.83	0.72	73.72
186	INT262151	Vdr Regulation of Cyp24a1	1	0.24	0.24	0.23	73.36
187	INT335132	PPARA Positive_regulation of Cyp4x1	1	0.25	0	0.08	73.08
188	INT283464	Binding of CD4 and DLAT	1	0.07	0.69	0.04	72.96
189	INT343571	Synm Positive_regulation of ALPP	1	0.01	1.28	0.28	72.88
190	INT343570	Synm Positive_regulation of Gpt	1	0.01	1.28	0.28	72.48
191	INT27690	Ins1 Negative_regulation of GYPA	1	0.00	0.73	0.69	72.40
192	INT327189	Gnat3 Regulation of Positive_regulation of PAEP	1	0.25	0.72	0.07	72.24
193	INT227418	Binding of DLAT and Pdc	1	0.05	1.01	0.07	72.12
194	INT343573	Synm Positive_regulation of SLC17A5	1	0.17	1.28	0.28	72.08
195	INT229394	TPSD1 Positive_regulation of F2RL1	2	0.00	3.11	2.14	71.84
196	INT107858	PRSS1 Positive_regulation of F2RL1	6	0.12	4.23	1.29	71.84
197	INT262161	Nr1i2 Positive_regulation of Gene_expression of Cyp27a1	1	0.29	0.24	0.07	71.72
198	INT321295	Negative_regulation of Fig4 Positive_regulation of Nr0b2	1	0.09	0.13	0.06	71.40
199	INT321288	Fig4 Positive_regulation of Nr0b2	1	0.15	0.47	0.27	70.96
200	INT321368	Fig4 Regulation of Fig4 Positive_regulation of Nr0b2	1	0.04	0.13	0.06	70.96

Single Events

The table below shows the top 200 pain related interactions that have been reported for bile. They are ordered first by their pain relevance and then by number of times they were reported in bile. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT251636	Gene_expression of Csf2rb2	1	0.33	9.64	8.34	100.00
2	INT287	Localization of Cck	518	0.81	86.84	364.04	100.00
3	INT145693	Gene_expression of Slc10a2	5	0.78	2.54	4.13	100.00
4	INT176190	Gene_expression of Abcg8	1	0.78	10.4	3.19	100.00
5	INT176177	Localization of Abcg8	1	0.81	3.79	2.14	100.00
6	INT2884	Positive_regulation of CCK	66	0.69	25.25	30.6	100.00
7	INT129901	Gene_expression of Nr1i2	60	0.73	22.44	6.04	100.00
8	INT251633	Positive_regulation of Csf2rb2	1	0.26	2.64	2.44	100.00
9	INT262117	Negative_regulation of Gene_expression of Cyp7a1	3	0.25	0.91	1.6	100.00
10	INT38025	Negative_regulation of Tlf	3	0.24	1.11	1.63	100.00
11	INT2862	Positive_regulation of Localization of Cck	108	0.70	20.75	94.25	100.00
12	INT251639	Positive_regulation of Gene_expression of Csf2rb2	1	0.21	1.73	1.66	100.00
13	INT2364	Localization of Sct	134	0.80	26.21	41.47	100.00
14	INT2463	Localization of CCK	101	0.81	37.54	47.59	100.00
15	INT183903	Binding of BAS	2	0.06	2.14	1.06	100.00
16	INT288	Positive_regulation of Sct	88	0.70	32.83	24.5	100.00
17	INT48993	Positive_regulation of Cftr	17	0.57	6.02	4.12	100.00
18	INT96724	Gene_expression of Cyp3a11	10	0.77	4.82	7.76	100.00
19	INT176183	Gene_expression of Abcg5	1	0.77	5.01	1.08	100.00
20	INT126748	Positive_regulation of Positive_regulation of Akt1	26	0.55	11.15	7.08	100.00
21	INT2885	Positive_regulation of Localization of CCK	19	0.70	9.92	8.94	100.00
22	INT81377	Gene_expression of Dpp4	8	0.71	5.15	2.51	100.00
23	INT1114	Localization of Ins1	748	0.80	192.95	165.48	100.00
24	INT2883	Negative_regulation of Localization of CCK	9	0.59	3.25	3.08	100.00
25	INT3948	Regulation of Cck	291	0.62	58.07	255.88	100.00
26	INT21990	Negative_regulation of Ctrc	17	0.42	8.45	4.47	100.00
27	INT11180	Binding of RYBP	52	0.46	13.86	42.53	100.00
28	INT251638	Binding of Csf2rb2	1	0.15	1.07	0.59	100.00
29	INT251643	Localization of Csf2rb2	1	0.28	0.75	0.86	100.00
30	INT170025	Gene_expression of Fig4	588	0.67	183.27	113.32	100.00
31	INT119892	Gene_expression of Cftr	54	0.77	23.76	9.73	100.00
32	INT28861	Binding of Gh	61	0.46	25.61	6.38	100.00
33	INT176041	Transcription of FABP6	1	0.05	0.64	0.59	100.00
34	INT130299	Gene_expression of Abcc2	2	0.58	0.61	0.95	100.00
35	INT137082	Regulation of ABCC2	2	0.16	1.11	0.85	100.00
36	INT99673	Localization of Cand1	1	0.73	0.15	0.62	100.00
37	INT39969	Localization of Kcne2	4	0.61	1.11	1.56	100.00
38	INT197010	Positive_regulation of CYP7A1	4	0.47	1.75	0.7	100.00
39	INT812	Localization of INS	1026	0.81	515.6	145.31	100.00
40	INT262057	Gene_expression of Slco1b2	1	0.20	0.24	0.44	100.00
41	INT257455	Binding of PDLIM5	2	0.08	1.72	0.64	100.00
42	INT251640	Regulation of Gene_expression of Csf2rb2	1	0.17	0.28	0.59	100.00
43	INT176191	Negative_regulation of Localization of Abcg8	1	0.43	1.06	0.42	100.00
44	INT121369	Negative_regulation of Gene_expression of MIF	3	0.50	2.48	0.92	100.00
45	INT139898	Negative_regulation of Positive_regulation of Akt1	15	0.42	4.66	4.06	100.00
46	INT39440	Negative_regulation of Bsp	3	0.38	0.52	2.24	100.00
47	INT251642	Protein_catabolism of Csf2rb2	1	0.33	0.48	0.45	100.00
48	INT35946	Positive_regulation of Clu	12	0.69	4.92	2.73	100.00
49	INT145692	Regulation of Gene_expression of Slc10a2	2	0.61	0.71	0.8	100.00
50	INT8153	Regulation of Localization of Cck	52	0.62	11.22	54.83	100.00
51	INT84997	Regulation of SLC10A2	1	0.20	0.13	0.37	100.00
52	INT686	Negative_regulation of Sct	35	0.59	9.59	11.32	100.00
53	INT131332	Negative_regulation of Gene_expression of Abcc2	7	0.58	1.25	2.35	100.00
54	INT4015	Positive_regulation of SCTR	5	0.37	6.45	1.62	100.00
55	INT321238	Transcription of Abcb11	1	0.53	0.22	0.27	100.00
56	INT176182	Transcription of Abcb4	2	0.43	0.49	0.27	100.00
57	INT2408	Regulation of CCK	37	0.61	10.01	26.66	100.00
58	INT42370	Negative_regulation of Ibsp	3	0.38	0.68	0.81	100.00
59	INT170900	Regulation of Positive_regulation of Gopc	10	0.20	3.44	1.24	100.00
60	INT334990	Regulation of Positive_regulation of Fgfr4	1	0.36	0.25	0.25	100.00
61	INT1988	Positive_regulation of Localization of Ins1	254	0.69	59.25	68.37	100.00
62	INT187499	Positive_regulation of Positive_regulation of Fig4	9	0.21	3.28	2.69	100.00
63	INT70563	Localization of ABCB1	14	0.78	2.03	3.09	100.00
64	INT8667	Localization of HSD11B1	22	0.73	22.74	1.25	100.00
65	INT209083	Positive_regulation of GPBAR1	1	0.01	0.84	0.41	100.00
66	INT171145	Positive_regulation of Fig4	274	0.59	93.55	69.81	100.00
67	INT10886	Positive_regulation of Cyp7a1	4	0.69	1.15	0.79	100.00
68	INT211534	Localization of Abcb11	2	0.61	0.15	0.18	100.00
69	INT47186	Localization of SCTR	8	0.50	5.07	1.55	100.00
70	INT10617	Positive_regulation of Localization of Uck1	1	0.03	0.66	0.94	100.00
71	INT6150	Positive_regulation of Negative_regulation of Calca	20	0.68	4.06	16.26	100.00
72	INT2275	Negative_regulation of Localization of Ins1	183	0.59	51.02	44.94	100.00
73	INT240671	Binding of SLC10A2	1	0.36	1.91	0.16	100.00
74	INT59862	Phosphorylation of CEL	2	0.70	0.53	0.3	100.00
75	INT322765	Negative_regulation of ABCB11	2	0.12	1.21	0.24	100.00
76	INT27135	Gene_expression of SAFB	9	0.68	0.96	0.79	100.00
77	INT211553	Gene_expression of Pltp	2	0.48	0.96	0.3	100.00
78	INT35636	Gene_expression of Sord	6	0.78	2.31	1.35	100.00
79	INT24332	Regulation of Hdl1	28	0.45	45.45	4.26	100.00
80	INT138691	Negative_regulation of OPN1MW	2	0.38	1.61	0.29	100.00
81	INT165690	Localization of Abcc2	4	0.79	1.31	1.38	100.00
82	INT22213	Localization of Gpt	52	0.78	34.05	12.94	100.00
83	INT58202	Regulation of TFF1	4	0.37	2.49	0.53	100.00
84	INT222400	Negative_regulation of Localization of INCENP	4	0.02	1.82	2.46	100.00
85	INT251637	Positive_regulation of Localization of Csf2rb2	1	0.19	0.48	0.31	100.00
86	INT1322	Positive_regulation of Localization of INS	293	0.70	120.86	45.98	100.00
87	INT73411	Positive_regulation of Pla2g2d	1	0.02	0	0.12	100.00
88	INT187328	Negative_regulation of C4bpa	2	0.12	0.07	0.26	100.00
89	INT145769	Negative_regulation of Localization of Abcc1	1	0.16	0.07	0.19	100.00
90	INT169553	Positive_regulation of Slc37a4	9	0.13	2.94	2.49	100.00
91	INT18527	Localization of Aap	31	0.72	5.6	14.42	100.00
92	INT88278	Binding of Kit	33	0.37	24.45	4.13	100.00
93	INT26878	Positive_regulation of Localization of Aap	2	0.48	0.48	3.19	100.00
94	INT211548	Gene_expression of Lpin1	9	0.76	12.83	0.96	100.00
95	INT211551	Gene_expression of Cyp8b1	1	0.69	0.31	0.1	100.00
96	INT118791	Binding of AKT1	32	0.48	15.51	2.25	100.00
97	INT19947	Negative_regulation of B3GAT2	10	0.57	4.2	7.95	100.00
98	INT274626	Positive_regulation of Positive_regulation of GRHL3	1	0.22	0.67	0.32	100.00
99	INT127962	Positive_regulation of GRHL3	3	0.32	2.67	3.69	100.00
100	INT46575	Gene_expression of SCTR	2	0.43	2.83	0.52	100.00
101	INT375	Positive_regulation of REN	293	0.70	152.46	47.55	100.00
102	INT9664	Binding of LBP	127	0.48	94.9	63.42	100.00
103	INT170470	Binding of CD14	27	0.35	14.89	5.16	100.00
104	INT287799	Positive_regulation of Gene_expression of AIP	1	0.42	7.39	1.19	100.00
105	INT111161	Positive_regulation of EFNA1	6	0.40	4.62	0.68	100.00
106	INT50490	Regulation of PTGS2	80	0.48	39.51	25.85	100.00
107	INT121374	Regulation of Gene_expression of MIF	2	0.39	1.01	0.29	100.00
108	INT121373	Regulation of ZNF398	1	0.00	0.63	0.25	100.00
109	INT256251	Regulation of Gene_expression of Hdl1	4	0.33	7.35	0.21	100.00
110	INT12159	Transcription of Cck	46	0.72	9.36	37.58	100.00
111	INT170823	Gene_expression of Gba2	1	0.58	0.35	0.29	100.00
112	INT36263	Positive_regulation of CEL	53	0.69	34.88	12.87	100.00
113	INT12191	Negative_regulation of Localization of Ldha	35	0.59	13.71	12.35	100.00
114	INT54701	Localization of Ptafr	19	0.49	18.68	3.82	100.00
115	INT89519	Negative_regulation of COL1A2	10	0.36	6.26	2.17	100.00
116	INT28054	Regulation of Ces2a	4	0.14	1.03	2.16	100.00
117	INT174653	Localization of MEFV	15	0.70	12.06	1.93	100.00
118	INT39144	Gene_expression of RIPK2	5	0.75	2.56	1.27	100.00
119	INT91122	Localization of CAT	6	0.78	4.13	1.19	100.00
120	INT4124	Regulation of Gusb	3	0.22	1.05	1.11	100.00
121	INT53852	Binding of Fabp1	1	0.02	0.21	0.85	100.00
122	INT12190	Negative_regulation of Localization of Got1	2	0.21	0.98	0.8	100.00
123	INT64827	Binding of Il2ra	5	0.36	6.57	0.79	100.00
124	INT28055	Positive_regulation of Ces2a	2	0.03	1.3	0.66	100.00
125	INT12192	Negative_regulation of Localization of Gpt	1	0.39	0.45	0.64	100.00
126	INT181888	Regulation of Apoa1	5	0.26	5.07	0.6	100.00
127	INT52875	Regulation of Engase	1	0.42	0.78	0.5	100.00
128	INT28052	Positive_regulation of Sult2al1	1	0.10	0	0.49	100.00
129	INT28053	Regulation of Sult2al1	1	0.14	0	0.48	100.00
130	INT190882	Regulation of Gene_expression of Apoa1	4	0.23	3.67	0.43	100.00
131	INT4014	Positive_regulation of Positive_regulation of SCTR	1	0.37	0.82	0.42	100.00
132	INT111164	Positive_regulation of Efna1	1	0.02	0.83	0.28	100.00
133	INT229971	Localization of C1S	3	0.68	2.91	0.28	100.00
134	INT17280	Localization of SPANXA1	2	0.06	0.88	0.25	100.00
135	INT9814	Localization of Ctrl	1	0.05	0.28	0.24	100.00
136	INT24756	Negative_regulation of Negative_regulation of B3GAT2	1	0.02	0.62	0.14	100.00
137	INT225696	Regulation of Gene_expression of Entpd2	1	0.12	0	0.12	100.00
138	INT263638	Localization of PLA1A	1	0.01	0.22	0.09	100.00
139	INT229303	Localization of FXR1	1	0.14	0.6	0.05	100.00
140	INT211530	Localization of Cyp8b1	1	0.63	0.15	0.05	100.00
141	INT121372	Positive_regulation of Gene_expression of MIF	17	0.60	14.78	4.73	99.98
142	INT42369	Localization of Ibsp	6	0.62	2.51	2.17	99.98
143	INT131240	Gene_expression of Sall3	5	0.65	0.32	0.68	99.98
144	INT3920	Localization of Ldha	241	0.81	83.08	58.72	99.98
145	INT12189	Localization of Gpt	8	0.73	3.63	3.92	99.98
146	INT68186	Gene_expression of GOT2	11	0.65	6.01	0.91	99.98
147	INT1767	Positive_regulation of PROC	83	0.67	54.14	17	99.98
148	INT3919	Localization of Got1	10	0.71	2.95	3.28	99.98
149	INT42368	Localization of Cyp2c22	1	0.14	0.48	0.27	99.98
150	INT327119	Gene_expression of HCCS	1	0.12	2.47	0.74	99.96
151	INT65520	Gene_expression of Reg1	4	0.20	1.45	1.97	99.92
152	INT18884	Regulation of RYBP	25	0.38	11.43	23.2	99.92
153	INT5279	Localization of Ggt1	9	0.81	2.8	1.99	99.92
154	INT327121	Positive_regulation of Gene_expression of HCCS	1	0.07	1.3	0.37	99.92
155	INT186199	Binding of SCARB1	3	0.37	5.25	0.21	99.92
156	INT176205	Gene_expression of Cyp7a1	8	0.69	2.5	2.45	99.88
157	INT169073	Positive_regulation of Nr1h4	8	0.47	2.44	2.45	99.88
158	INT290303	Localization of HPCAL1	1	0.04	1.2	0.52	99.88
159	INT107033	Gene_expression of Slc37a4	66	0.62	27.34	12.35	99.88
160	INT8106	Gene_expression of GGT1	31	0.75	18.65	6.1	99.88
161	INT262108	Negative_regulation of Positive_regulation of Nr1h4	1	0.15	0.14	0.22	99.88
162	INT4160	Gene_expression of Ces2a	3	0.17	2.64	1.1	99.88
163	INT176207	Positive_regulation of Nr1h3	2	0.45	0	0.2	99.88
164	INT173171	Gene_expression of CYP7A1	2	0.45	1.02	0.14	99.88
165	INT176176	Gene_expression of Abcb11	2	0.58	0.45	0.1	99.88
166	INT173188	Regulation of Gene_expression of CYP7A1	1	0.22	0.48	0.12	99.88
167	INT8465	Regulation of Ptgs1	100	0.57	36.03	44.41	99.88
168	INT171233	Binding of Ecm1	25	0.07	12.41	3.36	99.88
169	INT170831	Negative_regulation of Transcription of Slc10a2	1	0.58	0.11	0.86	99.86
170	INT304633	Positive_regulation of Phosphorylation of Ocln	2	0.28	0.19	0.47	99.86
171	INT321313	Regulation of Nr1h4	1	0.32	0.37	0.17	99.86
172	INT8360	Positive_regulation of Localization of Prss12	14	0.26	1.72	9.38	99.84
173	INT10546	Positive_regulation of Prss12	12	0.44	4.57	10.05	99.84
174	INT112459	Localization of Gba	12	0.80	1.45	6.4	99.84
175	INT335005	Regulation of Gene_expression of Fgf15	1	0.58	0.8	0.66	99.84
176	INT193334	Gene_expression of HPYR1	11	0.53	10.36	0.88	99.84
177	INT251634	Regulation of Csf2rb2	1	0.19	0.49	0.58	99.84
178	INT22907	Positive_regulation of Ggt1	33	0.67	17.82	5.28	99.84
179	INT58567	Negative_regulation of Positive_regulation of Prss12	2	0.21	0	1.21	99.84
180	INT117223	Gene_expression of TLR4	348	0.78	206.18	54.42	99.84
181	INT321348	Positive_regulation of Localization of Akt1	1	0.30	0.08	0.32	99.84
182	INT136692	Localization of Akt1	12	0.78	2.14	3.65	99.84
183	INT52062	Negative_regulation of PDK1	3	0.37	1.59	0.86	99.84
184	INT321316	Positive_regulation of Fgf15	1	0.49	0.22	0.29	99.84
185	INT131123	Gene_expression of Gba	22	0.78	3.74	3.14	99.84
186	INT91	Positive_regulation of Localization of Gast	96	0.70	23.22	29.36	99.84
187	INT353535	Gene_expression of Mitf	1	0.05	0.29	0.15	99.84
188	INT113913	Binding of Hephl1	23	0.27	1.57	0.19	99.84
189	INT211532	Localization of Ldlr	4	0.56	3.52	0.13	99.84
190	INT284117	Protein_catabolism of Epcam	2	0.43	3.01	0.31	99.84
191	INT55529	Negative_regulation of Gba	13	0.59	7.91	2.1	99.84
192	INT121366	Regulation of Transcription of Mif	1	0.02	0.61	0.24	99.84
193	INT207229	Protein_catabolism of HBM	4	0.02	1.52	0.17	99.84
194	INT229309	Binding of FXR1	1	0.07	0.58	0.05	99.84
195	INT2132	Localization of SCT	29	0.81	8.39	5.43	99.82
196	INT31582	Gene_expression of Hdl1	103	0.66	118.95	6.42	99.80
197	INT12616	Positive_regulation of REG1A	23	0.69	6.57	5.81	99.80
198	INT329893	Regulation of Positive_regulation of CYP8B1	1	0.37	0.18	0.16	99.80
199	INT28752	Localization of St18	1	0.00	0	0.19	99.80
200	INT28851	Negative_regulation of CTRC	4	0.27	1.21	0.73	99.80