P:cva

From wiki-pain
Revision as of 14:46, 28 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

pChart

Pain Term
Category Disorder
Synonyms Abdominal Aortic Aneurism, Abdominal Aortic Aneurysm, Aggravated Angina Pectoris, Aggravation Of Angina Pectoris, Aggravation Of Coronary Artery Disease, Angina, Angina At Rest, Angina Attack, Angina Attacks, Angina Like Pain, Angina Of Effort, Angina Pectoris, Angina Pectoris Aggravated, Anginal Pain, Anginal Pains, Anginal Symptoms, Anginal Syndrome, Arterial Aneurism, Arterial Aneurysm, Arterial Insufficiency, Arterial Insufficiency Coronary, Arterial Ischaemia, Arterial Ischemia, Brain Haemorrhage, Brain Haemorrhages, Brain Hemorrhage, Brain Hemorrhages, Capillary Fragility, Carditis Pericardium Myocardium, Cerebral Embolism, Cerebral Embolisms, Cerebral Haemorrhage, Cerebral Haemorrhages, Cerebral Hemorrhage, Cerebral Hemorrhages, Cerebral Hyperaemia, Cerebral Hyperemia, Cerebral Infarction, Cerebral Infarctions, Cerebral Vascular Accident, Cerebral Vascular Accidents, Cerebral Vascular Disturbance, Cerebral Vascular Disturbances, Cerebral Vascular Lesion, Cerebral Vascular Lesions, Cerebrovascular Accident, Cerebrovascular Accident Insufficiency, Cerebrovascular Disorder, Cerebrovascular Disorders, Cerebrovascular Events, Cerebrovascular Insufficiency, Coronary Arteriospasm, Coronary Arteriospasms, Coronary Artery Spasm, Coronary Spasm, Coronary Spasms, Crescendo Angina, Deep Multiple Thrombophlebitis, Deep Thrombophlebitis, Deep Thrombophlebitis Of The Arm, Deep Thrombophlebitis Of The Leg, Dissection Coronary Artery, Effort Angina, Embolism, Embolisms, Frank Haemorrhage, Frank Hemorrhage, Haemorrhage, Haemorrhage From Any Tissue Organ, Haemorrhages, Haemorrhagic Manifestation, Haemorrhagic Manifestations, Hemorrhage, Hemorrhage From Any Tissue Organ, Hemorrhages, Hemorrhagic Manifestation, Hemorrhagic Manifestations, Increased Angina, Increased Angina Pectoris, Increased Bleeding, Increased Intracranial Pressure With Papilledema, Increased Intracranial Pressure With Papilloedema, Intracranial Haemorrhage, Intracranial Haemorrhages, Intracranial Hemorrhage, Intracranial Hemorrhages, Intracranial Hypertension, Intracranial Pressure, Intracranial Pressure Increased, Lower Extremity Embolus, Multiple Thrombophlebitis, Neonatal Thrombophlebitis, Pancarditis, Pericarditis, Post Infarction Angina, Pressure Cerebrospinal Fluid Increased, Prinzmetal S Angina At Rest, Pseudotumor Cerebri, Pulmonary Embolus, Retroperitoneal Haemorrhage, Retroperitoneal Haemorrhages, Retroperitoneal Hemorrhage, Retroperitoneal Hemorrhages, Spontaneous Post Traumatic Bleeding, Superficial Thrombophlebitis, Superficial Thrombophlebitis Of The Arm, Superficial Thrombophlebitis Of The Leg, Thromboembolic, Thromboembolism, Thrombophlebitis, Thrombophlebitis At Injection Site, Thrombophlebitis In Peripheral Veins, Thrombophlebitis Of The Arm, Thrombophlebitis Of The Leg, Thrombophlebitis Of The Mesenteric Vein, Thrombophlebitis Of The Pelvic Vein, Thrombophlebitis Of The Retinal Vein, Thrombophlebitis Vena Cava, Unstable Angina, Worsening Of Angina Pectoris
Pain Specific No
Documents 22851
Hot Single Events 200
Hot Interactions 179

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for cva. They are ordered first by their pain relevance and then by number of times they were reported for cva. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14 100.00
2 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96 100.00
3 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73 100.00
4 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04 100.00
5 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65 100.00
6 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44 100.00
7 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13 100.00
8 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08 100.00
9 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19 100.00
10 INT278224 Binding of ACSM3 and SNRNP70 1 0.04 3.76 1.01 100.00
11 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48 100.00
12 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22 100.00
13 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 100.00
14 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59 100.00
15 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58 100.00
16 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57 100.00
17 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57 100.00
18 INT273244 Binding of VCF and Del(7)Tyr<c-23DVT>-p 1 0.00 2.94 0.55 100.00
19 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54 100.00
20 INT278227 Binding of MBNL1 and SNRNP70 1 0.01 2.05 0.54 100.00
21 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72 100.00
22 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51 100.00
23 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 100.00
24 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 100.00
25 INT334130 Negative_regulation of Acsm3 Positive_regulation of Mip 1 0.12 1.48 0.81 100.00
26 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27 100.00
27 INT334132 Acsm3 Positive_regulation of Gene_expression of Cxcl2 1 0.13 2.26 0.83 100.00
28 INT334134 Acsm3 Positive_regulation of Gene_expression of Mip 1 0.13 1.4 0.77 100.00
29 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66 100.00
30 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66 100.00
31 INT334128 Acsm3 Positive_regulation of Sele 1 0.16 1.6 0.66 100.00
32 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 100.00
33 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4 100.00
34 INT16677 Binding of Avp and Oprd1 1 0.02 0.8 0.47 100.00
35 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2 100.00
36 INT332741 BPIFA1 Negative_regulation of ENO1 1 0.32 0.99 0.17 100.00
37 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 100.00
38 INT244325 Csf2 Regulation of Positive_regulation of Aliq1 1 0.03 1.02 0.33 100.00
39 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 100.00
40 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 100.00
41 INT332740 Binding of ENO1 and BPIFA1 1 0.31 0.71 0.09 100.00
42 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13 100.00
43 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54 99.98
44 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 99.98
45 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85 99.92
46 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34 99.92
47 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48 99.92
48 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58 99.90
49 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 99.90
50 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93 99.90
51 INT328429 PRB4 Negative_regulation of Gene_expression of AKT1 1 0.03 0.52 0.05 99.88
52 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37 99.82
53 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61 99.76
54 INT170158 NPPA Positive_regulation of Gene_expression of NPPB 1 0.13 0.91 0.23 99.72
55 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14 99.72
56 INT230775 CEBPZ Regulation of CPP 1 0.11 0.69 0.27 99.56
57 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36 99.40
58 INT278225 Binding of FOSB and SNRNP70 1 0.00 1.22 0.36 99.40
59 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3 99.22
60 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28 99.12
61 INT348756 Gopc Positive_regulation of Gene_expression of Mmp9 1 0.10 0.77 0.17 99.12
62 INT259934 Plat Positive_regulation of Gene_expression of Mmp9 2 0.33 1.05 0.17 99.12
63 INT328499 Binding of Cebpz and Sumo1 1 0.08 0.84 0.27 99.00
64 INT254161 Epo Positive_regulation of Nos2 1 0.37 0.54 0.05 99.00
65 INT254162 Epo Positive_regulation of NOS1 1 0.01 0.53 0.05 99.00
66 INT170157 NPPC Regulation of CSF2 1 0.12 1.36 0.42 98.56
67 INT328501 Sumo1 Negative_regulation of Gene_expression of Pglyrp1 1 0.00 1.54 0.83 98.28
68 INT294207 Serpine1 Regulation of Gene_expression of Plat 1 0.50 0.92 0.16 98.20
69 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 97.64
70 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 97.56
71 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87 97.36
72 INT56904 Binding of GCY and ICA1 1 0.15 1.5 0.28 97.32
73 INT118136 Binding of HTR1A and HTR2A 1 0.36 0.77 0.45 97.12
74 INT353318 NOS1 Positive_regulation of Localization of Tbxa2r 1 0.04 0.71 0.12 96.92
75 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27 96.88
76 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2 96.88
77 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05 96.52
78 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28 96.00
79 INT274531 Il6 Regulation of Localization of Lpl 1 0.04 1.49 0.33 95.80
80 INT274530 Il6 Regulation of Lpl 1 0.07 1.48 0.32 95.80
81 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29 95.80
82 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28 95.80
83 INT247078 Binding of F5 and PTBP1 1 0.02 0.44 0.14 95.80
84 INT199130 PRSS1 Positive_regulation of Prss1 1 0.15 0.8 0.09 95.68
85 INT311733 Plat Regulation of Protein_catabolism of Orai1 1 0.28 0.71 0.13 95.64
86 INT311727 Plat Regulation of Protein_catabolism of Col17a1 1 0.31 0.71 0.13 95.64
87 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13 95.64
88 INT311731 Plat Regulation of Protein_catabolism of Pik3cd 1 0.31 0.71 0.13 95.64
89 INT310302 Tlr4 Regulation of Positive_regulation of Serpina10 1 0.01 0.53 0.18 95.00
90 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32 94.60
91 INT353669 Binding of SNRNP70 and CD209 1 0.04 6.08 0.35 94.08
92 INT245986 MTR Regulation of Mthfr 1 0.07 0.18 0.05 94.08
93 INT245981 Negative_regulation of TCN1 Regulation of Mthfr 1 0.03 0.18 0.05 94.08
94 INT245984 TCN1 Regulation of Mtrr 1 0.02 0.18 0.05 94.08
95 INT245966 TCN1 Regulation of MTR 1 0.02 0.18 0.05 94.08
96 INT245982 TCN1 Regulation of Mthfr 1 0.04 0.18 0.05 94.08
97 INT245983 Negative_regulation of TCN1 Regulation of Mtrr 1 0.02 0.18 0.05 94.08
98 INT245967 Negative_regulation of TCN1 Regulation of MTR 1 0.02 0.18 0.05 94.08
99 INT245974 Mtrr Regulation of Mthfr 1 0.07 0.18 0.05 94.08
100 INT4987 Vim Positive_regulation of Lrrc23 1 0.00 0.42 0.14 94.00
101 INT123468 IL6 Regulation of CSF2 1 0.25 1.22 0.26 93.88
102 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22 93.00
103 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 92.88
104 INT287438 HTS Negative_regulation of Nfkb1 1 0.01 1.77 0.37 92.80
105 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18 92.40
106 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25 92.32
107 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26 92.24
108 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12 91.88
109 INT328426 PRB4 Positive_regulation of GOPC 1 0.03 0.55 0.05 91.68
110 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 91.36
111 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13 91.36
112 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18 91.08
113 INT249954 Cpa1 Positive_regulation of Nos3 1 0.04 0.36 0.05 90.72
114 INT202930 Binding of LAMB1 and Fbln5 1 0.01 0.45 0.05 90.28
115 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38 90.20
116 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17 90.12
117 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 90.08
118 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39 90.00
119 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 90.00
120 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95 89.68
121 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 89.64
122 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38 89.56
123 INT149882 Binding of Ptgs1 and Ptges 1 0.01 0.15 0.22 89.36
124 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08 89.24
125 INT273055 Plat Positive_regulation of Gene_expression of Nos2 1 0.01 1.34 0.23 89.24
126 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95 88.56
127 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04 88.56
128 INT316129 Binding of HLA-DRA and IL10 1 0.12 3.1 0.17 88.48
129 INT199128 Ctsb Positive_regulation of Prss1 1 0.02 0.9 0.15 88.36
130 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38 88.28
131 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16 88.16
132 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15 88.16
133 INT325998 Negative_regulation of Cybb Negative_regulation of Gene_expression of Ros1 1 0.06 1.3 0.11 87.96
134 INT170159 Negative_regulation of NPPC Regulation of CSF2 1 0.20 0.33 0.11 87.68
135 INT49058 Binding of IGHE and Positive_regulation of Localization of PTGDS 1 0.29 0.35 0.17 87.44
136 INT199129 Ctsb Positive_regulation of PRSS1 1 0.01 0.9 0.15 87.24
137 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 87.04
138 INT239393 Atp7b Positive_regulation of Gene_expression of Amigo2 1 0.03 1.37 0.16 87.04
139 INT46308 Asrgl1 Positive_regulation of Gene_expression of Serpinc1 1 0.01 1.07 0.19 86.00
140 INT46306 Asrgl1 Positive_regulation of Negative_regulation of Plg 1 0.01 1.07 0.19 86.00
141 INT46307 Asrgl1 Positive_regulation of Negative_regulation of Serpinc1 1 0.01 1.07 0.19 86.00
142 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82 85.44
143 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16 85.28
144 INT324871 Ros1 Positive_regulation of Gene_expression of Tlr2 1 0.03 1.12 0.07 84.92
145 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04 84.72
146 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04 84.72
147 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16 84.68
148 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16 84.68
149 INT343484 Epo Regulation of Gene_expression of VEGFA 1 0.24 0.41 0.16 84.68
150 INT320695 TNF Positive_regulation of Localization of Il1 1 0.05 1.38 0.44 84.56
151 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 84.48
152 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44 84.40
153 INT212078 Eno2 Regulation of Localization of EPHB6 1 0.03 0.52 0.07 83.92
154 INT212068 CHGA Regulation of Localization of EPHB6 1 0.49 0.52 0.07 83.92
155 INT212069 SYP Regulation of Localization of EPHB6 1 0.49 0.52 0.07 83.92
156 INT212066 ENO2 Regulation of Localization of EPHB6 1 0.49 0.52 0.07 83.92
157 INT212071 Eno2 Regulation of Localization of Afp 1 0.01 0.52 0.07 83.20
158 INT212079 SYP Regulation of Localization of Afp 1 0.10 0.52 0.07 83.20
159 INT212077 CHGA Regulation of Localization of Afp 1 0.10 0.52 0.07 83.20
160 INT212076 ENO2 Regulation of Localization of Afp 1 0.10 0.52 0.07 83.20
161 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38 82.88
162 INT212070 ENO2 Regulation of Localization of AFP 1 0.49 0.52 0.07 82.80
163 INT212067 CHGA Regulation of Localization of AFP 1 0.49 0.52 0.07 82.80
164 INT212081 Eno2 Regulation of Localization of AFP 1 0.03 0.52 0.07 82.80
165 INT212062 SYP Regulation of Localization of AFP 1 0.49 0.52 0.07 82.80
166 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19 82.64
167 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19 82.64
168 INT220682 tf Positive_regulation of Positive_regulation of F10 1 0.04 0.67 0.19 81.96
169 INT220673 Binding of tf and Gtf3a Positive_regulation of F10 1 0.00 0.67 0.19 81.96
170 INT220675 Binding of tf and Gtf3a 1 0.02 0.67 0.19 81.96
171 INT213239 Binding of TNXA and Serpinc1 1 0.00 0.16 0.08 81.84
172 INT310310 Serpina10 Regulation of Gene_expression of Nos2 1 0.01 0.24 0.08 81.76
173 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 81.44
174 INT348637 Binding of TLE4 and OLFM1 1 0.01 1.67 0.24 81.36
175 INT212080 Eno2 Regulation of Localization of SYP 1 0.03 0.51 0.07 81.04
176 INT212063 CHGA Regulation of Localization of SYP 1 0.49 0.51 0.07 81.04
177 INT212064 ENO2 Regulation of Localization of SYP 1 0.49 0.51 0.07 81.04
178 INT202927 Binding of Fbln2 and Fbn1 1 0.14 0.29 0.04 80.48
179 INT92247 Binding of F13a1 and Fgg 1 0.00 0.68 0.14 80.16
180 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 79.76
181 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 79.76
182 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 79.76
183 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 79.76
184 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 79.76
185 INT239395 Atp7b Positive_regulation of Amigo2 1 0.03 1.36 0.16 79.56
186 INT239394 Atp7b Positive_regulation of Positive_regulation of Amigo2 1 0.03 1.36 0.16 79.56
187 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 79.40
188 INT202928 Binding of Eln and Fbln2 1 0.11 0.29 0.04 79.20
189 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 78.92
190 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 78.80
191 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 78.72
192 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 78.40
193 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 78.28
194 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15 78.16
195 INT81159 Binding of PARP1 and IgG-2a 1 0.00 1.02 0.21 77.92
196 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22 77.92
197 INT202807 Pin1 Regulation of Binding of Hnrpd 1 0.06 0.14 0.08 77.92
198 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 77.72
199 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05 77.60
200 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07 77.48

Single Events

The table below shows the top 200 pain related interactions that have been reported for cva. They are ordered first by their pain relevance and then by number of times they were reported in cva. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 100.00
2 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 100.00
3 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 100.00
4 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 100.00
5 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 100.00
6 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 100.00
7 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 100.00
8 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
9 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 100.00
10 INT15470 Regulation of CPP 42 0.48 26.1 18.25 100.00
11 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 100.00
12 INT47909 Binding of CPP 32 0.48 24.9 13.79 100.00
13 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 100.00
14 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06 100.00
15 INT168479 Binding of BAG3 13 0.36 10.68 4.21 100.00
16 INT202976 Positive_regulation of STC2 1 0.04 9.73 3.78 100.00
17 INT178037 Gene_expression of Del(7)Tyr<c-23DVT>-p 18 0.22 23.44 4.07 100.00
18 INT202977 Binding of STC2 1 0.02 8.53 3.31 100.00
19 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
20 INT184894 Localization of MCRS1 9 0.47 10.04 3.31 100.00
21 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
22 INT201477 Positive_regulation of Acsm3 8 0.31 15 5.38 100.00
23 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91 100.00
24 INT27345 Positive_regulation of ANIB1 9 0.07 9.81 3.46 100.00
25 INT172592 Positive_regulation of PTH1R 9 0.28 6.25 2.5 100.00
26 INT103463 Localization of CPP 16 0.66 9.63 4.08 100.00
27 INT10924 Positive_regulation of Sysbp1 25 0.04 11.12 7.35 100.00
28 INT2330 Regulation of CB 78 0.10 20.46 32.6 100.00
29 INT3244 Negative_regulation of eCB 37 0.03 16.69 12.61 100.00
30 INT102698 Binding of ACCS 54 0.42 66.73 9.06 100.00
31 INT1116 Regulation of Ren 103 0.62 27.66 33.26 100.00
32 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 100.00
33 INT53020 Positive_regulation of ACSM3 9 0.58 11.03 2.73 100.00
34 INT35584 Binding of ACLY 22 0.35 31.78 7.17 100.00
35 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 100.00
36 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
37 INT70970 Binding of COPD 144 0.42 180.34 18.29 100.00
38 INT46 Localization of Ren 233 0.81 46.15 62.44 100.00
39 INT296095 Negative_regulation of Positive_regulation of Acsm3 1 0.14 4.41 1.94 100.00
40 INT37834 Negative_regulation of Positive_regulation of CPP 14 0.58 6.22 5.69 100.00
41 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
42 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 100.00
43 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 100.00
44 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 100.00
45 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23 100.00
46 INT159673 Positive_regulation of Localization of CPP 4 0.41 3.43 1.34 100.00
47 INT216365 Gene_expression of CASP2 8 0.65 3.27 2.75 100.00
48 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
49 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02 100.00
50 INT27346 Regulation of ANIB1 5 0.03 3.47 1.47 100.00
51 INT287307 Binding of ENO1 9 0.48 11.24 2.51 100.00
52 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99 100.00
53 INT8960 Binding of SDHB 9 0.36 9.2 1.68 100.00
54 INT106805 Localization of ACCS 15 0.53 15.22 3.98 100.00
55 INT53468 Binding of Acsm3 26 0.24 20.87 2.95 100.00
56 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 100.00
57 INT104756 Gene_expression of ACSM3 8 0.58 8.76 1.83 100.00
58 INT104495 Regulation of Positive_regulation of Taok3 1 0.21 1.88 1.28 100.00
59 INT58918 Gene_expression of SDHB 5 0.75 2.93 1.27 100.00
60 INT128868 Positive_regulation of Mcrs1 3 0.03 3.26 2.31 100.00
61 INT200554 Positive_regulation of Aliq1 29 0.22 33.02 5.32 100.00
62 INT212093 Positive_regulation of CASP2 6 0.17 6.87 1.14 100.00
63 INT217072 Negative_regulation of Acsm3 5 0.29 6.15 1.59 100.00
64 INT130517 Positive_regulation of AIRN 14 0.30 1.77 1.31 100.00
65 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92 100.00
66 INT37006 Regulation of S100a4 2 0.13 1.74 1.21 100.00
67 INT61714 Binding of FGD1 12 0.35 7.72 2.91 100.00
68 INT38625 Gene_expression of ELL 8 0.58 12.53 1 100.00
69 INT287308 Negative_regulation of ENO1 5 0.59 4.07 1.24 100.00
70 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 100.00
71 INT235746 Positive_regulation of Casp2 2 0.04 2.67 0.67 100.00
72 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 100.00
73 INT262276 Negative_regulation of CASP2 1 0.01 2.98 0.73 100.00
74 INT170163 Negative_regulation of ACSM3 5 0.16 3.56 0.96 100.00
75 INT175914 Positive_regulation of Iph1 1 0.01 3.18 0.82 100.00
76 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 100.00
77 INT17486 Negative_regulation of Positive_regulation of Sysbp1 1 0.00 1.12 0.71 100.00
78 INT9748 Negative_regulation of Sysbp1 28 0.35 8.93 3.87 100.00
79 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 100.00
80 INT94028 Regulation of Twist1 37 0.44 22.41 5.33 100.00
81 INT332744 Regulation of ENO1 1 0.47 1.76 0.43 100.00
82 INT104485 Regulation of Taok3 1 0.09 0.94 0.63 100.00
83 INT9950 Gene_expression of OTOR 11 0.65 10.05 2.23 100.00
84 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
85 INT34184 Localization of FGD1 7 0.65 2.68 4.21 100.00
86 INT305618 Regulation of Gene_expression of MCRS1 1 0.04 1.24 0.43 100.00
87 INT136642 Positive_regulation of T(1;9)27H 1 0.19 1.11 0.96 100.00
88 INT315892 Negative_regulation of Binding of ATM 1 0.07 1.41 0.4 100.00
89 INT48212 Binding of ATM 5 0.47 3.89 0.57 100.00
90 INT213743 Negative_regulation of Amigo2 2 0.06 3.56 0.64 100.00
91 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83 100.00
92 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26 100.00
93 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01 100.00
94 INT296651 Negative_regulation of Casp2 2 0.21 1.75 0.35 100.00
95 INT296093 Positive_regulation of Gene_expression of Acsm3 1 0.19 1.11 0.4 100.00
96 INT57147 Binding of ANIB1 3 0.31 1.65 0.44 100.00
97 INT32532 Regulation of Positive_regulation of Pomc 11 0.61 3.2 5.93 100.00
98 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 100.00
99 INT175915 Negative_regulation of Positive_regulation of Iph1 1 0.01 1.67 0.42 100.00
100 INT202982 Transcription of MCRS1 1 0.25 1.19 0.33 100.00
101 INT156724 Positive_regulation of Positive_regulation of CPP 3 0.40 1.08 0.74 100.00
102 INT18025 Binding of Pah 32 0.45 30.72 7.93 100.00
103 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 100.00
104 INT54777 Positive_regulation of Bp28 1 0.01 0.94 0.77 100.00
105 INT54778 Regulation of Positive_regulation of Bp28 1 0.01 0.94 0.77 100.00
106 INT54780 Regulation of Bp28 1 0.01 0.94 0.77 100.00
107 INT305619 Negative_regulation of Regulation of MCRS1 1 0.04 1.35 0.35 100.00
108 INT54779 Binding of Bp28 1 0.01 0.93 0.7 100.00
109 INT262277 Regulation of CASP2 1 0.01 1.27 0.33 100.00
110 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 100.00
111 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 100.00
112 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49 100.00
113 INT150060 Localization of ACSM3 1 0.68 1.16 0.52 100.00
114 INT163969 Positive_regulation of Hypt 6 0.41 6.24 0.49 100.00
115 INT4652 Gene_expression of CB 13 0.32 7.41 5.57 100.00
116 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 100.00
117 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52 100.00
118 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
119 INT230778 Positive_regulation of Positive_regulation of MCRS1 1 0.03 0.75 0.27 100.00
120 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
121 INT17673 Negative_regulation of Localization of Lnpep 8 0.09 2.63 3.12 100.00
122 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
123 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 100.00
124 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 100.00
125 INT244315 Positive_regulation of Positive_regulation of Aliq1 1 0.04 2.94 0.5 100.00
126 INT331990 Negative_regulation of Ichs 1 0.11 0.89 0.21 100.00
127 INT120220 Gene_expression of ANIB1 4 0.65 1.82 1.92 100.00
128 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 100.00
129 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 100.00
130 INT11686 Regulation of IL3 15 0.45 8.69 2.54 100.00
131 INT356020 Binding of MKS1 1 0.02 1.36 0.2 100.00
132 INT244300 Localization of PTH1R 2 0.74 2.03 0.67 100.00
133 INT142761 Positive_regulation of TAs 6 0.40 2.28 2.61 100.00
134 INT39463 Positive_regulation of Tg 15 0.69 11.49 2.46 100.00
135 INT171995 Binding of PTH1R 8 0.35 1.16 0.31 100.00
136 INT296646 Transcription of Casp2 1 0.03 0.71 0.17 100.00
137 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 100.00
138 INT207451 Binding of PLA2G7 3 0.48 11.12 1.32 100.00
139 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39 100.00
140 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52 100.00
141 INT175916 Binding of Iph1 1 0.01 1.84 0.19 100.00
142 INT76957 Negative_regulation of ITGB3 6 0.57 2.82 1.13 100.00
143 INT163470 Localization of CMAHP 1 0.61 1.38 0.32 100.00
144 INT137976 Positive_regulation of ENTPD1 6 0.59 6.74 1.63 100.00
145 INT55284 Regulation of CTPP 3 0.60 1.07 1.31 100.00
146 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
147 INT17174 Transcription of F13A1 5 0.52 1.87 0.98 100.00
148 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46 100.00
149 INT244102 Phosphorylation of ACSM3 1 0.31 0.73 0.12 100.00
150 INT174986 Gene_expression of AIRN 20 0.57 6.13 0.64 100.00
151 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 100.00
152 INT317091 Localization of ENO1 1 0.65 0.32 0.1 100.00
153 INT180031 Gene_expression of IBGC1 1 0.05 1.38 0.2 100.00
154 INT311689 Positive_regulation of 119L04aR 2 0.01 1.09 0.1 100.00
155 INT261203 Binding of HTs 5 0.32 3.01 0.71 100.00
156 INT296650 Gene_expression of Casp2 2 0.30 1.49 0.17 100.00
157 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 100.00
158 INT184892 Positive_regulation of Localization of MCRS1 2 0.22 1.24 0.16 100.00
159 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
160 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 100.00
161 INT96 Binding of Adrb1 18 0.48 2.8 8.52 100.00
162 INT23034 Positive_regulation of Il1a 15 0.70 8.75 6.29 100.00
163 INT106433 Regulation of CCR5 11 0.59 6.93 2.75 100.00
164 INT171070 Positive_regulation of Hey2 8 0.05 10.12 1.96 100.00
165 INT56446 Positive_regulation of Positive_regulation of Icam1 7 0.40 8.84 1.64 100.00
166 INT30314 Negative_regulation of Ptgir 3 0.34 1.08 0.76 100.00
167 INT50061 Negative_regulation of Edn3 4 0.58 0.77 0.65 100.00
168 INT324672 Negative_regulation of Gene_expression of CEBPZ 2 0.36 2.75 0.48 100.00
169 INT68338 Gene_expression of PLEC 4 0.75 0.44 0.32 100.00
170 INT178765 Positive_regulation of Localization of GET4 1 0.17 1.17 0.05 100.00
171 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.98
172 INT477 Localization of Avp 813 0.81 131.58 300.4 99.98
173 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.98
174 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.98
175 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.98
176 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 99.98
177 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.98
178 INT252562 Positive_regulation of Sae1 1 0.03 3.4 0.99 99.98
179 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 99.98
180 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 99.98
181 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88 99.98
182 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84 99.98
183 INT104491 Positive_regulation of Phosphorylation of S100a4 1 0.14 0.85 0.65 99.98
184 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.98
185 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 99.98
186 INT79894 Gene_expression of Sae1 2 0.11 1.65 0.54 99.98
187 INT334126 Positive_regulation of Positive_regulation of Mip 1 0.20 1.65 0.67 99.98
188 INT319704 Negative_regulation of Binding of Rela 1 0.05 0.51 0.26 99.98
189 INT319719 Negative_regulation of Binding of Crebbp 1 0.14 0.51 0.26 99.98
190 INT254136 Regulation of PLEC 1 0.23 0.33 0.13 99.98
191 INT178767 Localization of GET4 1 0.26 1.15 0.05 99.98
192 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.96
193 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 99.96
194 INT46714 Positive_regulation of TNNC1 76 0.67 75.99 6.66 99.96
195 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 99.96
196 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97 99.96
197 INT296645 Positive_regulation of Gene_expression of Trpm2 1 0.48 1.25 0.3 99.96
198 INT77589 Negative_regulation of Negative_regulation of cerebral blood flow 1 0.00 0.57 0.29 99.96
199 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48 99.96
200 INT102836 Binding of LRP2 12 0.38 11.27 5.58 99.96
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox