Y:1989

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This page displays the top molecular interactions and top single events that were mentioned in the literature in 1989. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported in 1989. They are ordered first by their pain relevance and then by number of times they were reported in 1989. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in 1989 Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 3 0.64 2.12 14.2
2 INT10268 Binding of PDYN and POMC 11 1 0.39 0.08 10.36
3 INT26468 Ghrh Positive_regulation of Localization of Gh 21 1 0.37 3.26 9.21
4 INT26824 Crh Positive_regulation of Localization of Penk 7 6 0.54 0.42 6.49
5 INT20133 Trh Positive_regulation of Localization of Prl 23 2 0.78 2.04 5.44
6 INT11599 Calca Positive_regulation of Npr1 5 3 0.19 0.3 4.8
7 INT24742 Binding of Calca and Vip 1 4 0.37 0.18 4.68
8 INT1390 Trh Positive_regulation of Prl 14 3 0.67 4.42 4.39
9 INT11613 Cck Positive_regulation of Localization of Oxt 3 1 0.53 0 4.17
10 INT15984 Binding of Avp and Oxt 11 2 0.32 1.33 3.64
11 INT13729 GHRH Positive_regulation of Localization of GH1 13 1 0.62 0.59 3.2
12 INT26677 Penk Regulation of Localization of Trh 5 2 0.50 0 3.05
13 INT28235 Binding of Cck and Gast 5 1 0.38 0.73 2.96
14 INT25708 Oprl1 Positive_regulation of Adra2a 1 1 0.25 0.15 2.63
15 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 2 0.12 0 2.53
16 INT20411 Ghrh Positive_regulation of Gh1 6 1 0.56 0.62 2.47
17 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 1 0.46 0 2.23
18 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 1 0.38 0.16 2.16
19 INT18791 Crh Regulation of Penk 2 1 0.49 0 2.15
20 INT28387 Pomc Positive_regulation of Localization of LH 2 1 0.40 0.28 2.07
21 INT26222 Calca Positive_regulation of Calca Regulation of Gt(pU21)50Imeg 1 1 0.01 0 2.02
22 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 1 0.01 0 2.02
23 INT26948 Pomc Positive_regulation of Localization of Gh1 2 1 0.22 0.15 1.99
24 INT24942 Calca Regulation of TAC1 1 4 0.13 0.7 1.89
25 INT19496 Pomc Regulation of Localization of Ins1 1 2 0.55 0.33 1.82
26 INT24934 Calca Regulation of Nka1 3 2 0.05 0.43 1.73
27 INT26676 Pomc Regulation of Localization of Trh 3 2 0.14 0 1.73
28 INT27788 Gnrh1 Positive_regulation of Positive_regulation of LH 3 1 0.55 0.17 1.72
29 INT24817 Binding of POMC and VTN 8 7 0.42 0.39 1.71
30 INT24689 Binding of PLAT and Serpine1 1 7 0.00 3.77 1.64
31 INT26985 Cpe Negative_regulation of Localization of Ins1 1 2 0.02 0 1.57
32 INT27932 Binding of CCK and NCOR2 1 2 0.01 0.91 1.47
33 INT1314 Pomc Regulation of Localization of Gnrhr 2 1 0.16 0.14 1.45
34 INT26893 OGG1 Negative_regulation of Gh1 1 1 0.12 0 1.37
35 INT26812 SST Regulation of Localization of OXT 1 2 0.40 0.57 1.37
36 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 2 0.06 0 1.3
37 INT18324 Sst Negative_regulation of Localization of Ins1 2 2 0.46 1.09 1.24
38 INT25660 Binding of Penk and Pag1 1 1 0.01 0.67 1.19
39 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 1 0.00 0 1.18
40 INT27622 LOC360919 Positive_regulation of Protein_catabolism of Mbis1 1 1 0.00 0 1.18
41 INT25112 RYBP Negative_regulation of Binding of PLEKHM1 and 1 1 0.01 0 1.17
42 INT8308 Gnrh1 Regulation of Localization of LH 4 1 0.27 0 1.16
43 INT24796 ACE Positive_regulation of Localization of HMMR 1 2 0.00 0.58 1.16
44 INT25109 Negative_regulation of COL7A1 Positive_regulation of PLEKHM1 1 1 0.01 0 1.16
45 INT25026 PLOD1 Regulation of FSHR 4 1 0.19 0.38 1.15
46 INT25114 COL7A1 Positive_regulation of PLEKHM1 1 1 0.01 0 1.15
47 INT22176 Calca Regulation of Localization of Prl 4 1 0.69 0.39 1.11
48 INT25036 TRH Regulation of Prl 4 1 0.27 1.75 1.09
49 INT28186 CYP2E1 Regulation of Positive_regulation of RYBP 1 1 0.04 0.33 1.08
50 INT28657 Calca Regulation of Ghrh Positive_regulation of Gh1 1 1 0.19 0 1.05
51 INT25837 Binding of Dbp and Oprl1 1 1 0.10 0 1.05
52 INT19494 Pomc Positive_regulation of Localization of Ins1 2 1 0.62 0.38 1.02
53 INT25113 RYBP Negative_regulation of Binding of PTGER2 and 1 1 0.05 0 1.02
54 INT25155 TRH Positive_regulation of PRL 2 1 0.50 0.4 1
55 INT25111 Binding of PTGDS and PLEKHM1 1 1 0.01 0 0.97
56 INT25272 Binding of Ggh and Ghrh 1 1 0.22 0 0.97
57 INT24938 TAC1 Regulation of Calca 1 2 0.22 0.35 0.94
58 INT24939 TAC3 Regulation of Calca 1 2 0.01 0.35 0.94
59 INT27775 Binding of LH and Tst 1 1 0.25 0 0.93
60 INT24941 TAC3 Regulation of Nka1 1 2 0.00 0.34 0.92
61 INT25110 RYBP Negative_regulation of MTHFS 1 1 0.02 0 0.92
62 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 1 0.19 0 0.91
63 INT28921 Adra2a Positive_regulation of Localization of Prl 1 2 0.24 0 0.9
64 INT26991 Pomc Negative_regulation of Localization of Ins1 1 1 0.38 0 0.89
65 INT28194 Nppb Positive_regulation of CYP2B6 1 1 0.50 0.05 0.88
66 INT28193 Nppb Positive_regulation of Positive_regulation of RYBP 1 1 0.29 0.05 0.88
67 INT28192 Nppb Positive_regulation of CYP2B6 Positive_regulation of Positive_regulation of RYBP 1 1 0.33 0.05 0.88
68 INT28655 Calca Negative_regulation of Localization of Gh1 1 1 0.34 0 0.88
69 INT26987 Pomc Regulation of Ins1 1 1 0.40 0 0.87
70 INT24940 TAC1 Regulation of Nka1 1 2 0.10 0.34 0.87
71 INT26984 Cpe Regulation of Ins1 1 1 0.02 0 0.87
72 INT26529 Prl Regulation of Avp 1 1 0.08 0.26 0.85
73 INT25239 Ugt1a2 Positive_regulation of Ugt2b 1 1 0.30 0 0.85
74 INT26528 Prl Regulation of Oxt 1 1 0.26 0.26 0.85
75 INT28654 Calca Regulation of Localization of Gh1 1 1 0.36 0 0.84
76 INT28185 CYP2B6 Positive_regulation of Positive_regulation of RYBP 1 1 0.29 0 0.82
77 INT16933 Tsc22d3 Positive_regulation of Localization of Penk 2 1 0.24 0 0.76
78 INT28187 CYP2B6 Positive_regulation of RYBP 1 1 0.31 0.35 0.76
79 INT28620 Penk Regulation of Crh 2 1 0.40 0.25 0.75
80 INT26982 Cpe Regulation of Localization of Pomc 1 1 0.01 0 0.75
81 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 3 0.44 1.5 0.75
82 INT26983 Cpe Regulation of Localization of Ins1 1 1 0.02 0 0.75
83 INT17528 Prl Regulation of Gh 2 1 0.28 1.28 0.73
84 INT26986 Cpe Regulation of Pomc 1 1 0.01 0 0.73
85 INT26990 Pomc Regulation of Cpe 1 1 0.01 0 0.73
86 INT24967 Olr567 Regulation of Localization of Syt17 1 1 0.11 0.62 0.71
87 INT26872 ABAT Positive_regulation of Localization of POMC 1 1 0.03 0 0.71
88 INT27034 HERPUD1 Regulation of Gene_expression of IL2 1 2 0.38 0 0.71
89 INT28184 Binding of CYP1A2 and CYP2D6 1 1 0.00 0 0.7
90 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 1 0.38 0 0.7
91 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 1 0.22 3.78 0.69
92 INT28711 Binding of HLA-B and MRAP 2 1 0.23 0.96 0.69
93 INT27690 Ins1 Negative_regulation of GYPA 1 1 0.00 0.73 0.69
94 INT26230 Binding of GSR and HTR1D 1 2 0.12 0.15 0.69
95 INT26231 Binding of GSR and HTR1B 1 2 0.12 0.15 0.66
96 INT28079 POMC Regulation of ANPEP 1 1 0.08 0.16 0.66
97 INT28080 POMC Negative_regulation of Gene_expression of ITGAM 1 1 0.00 0.16 0.65
98 INT27526 Binding of Sdcbp and Eda 1 2 0.13 0 0.65
99 INT27426 Mtr Positive_regulation of Localization of Il1f5 1 1 0.06 0 0.63
100 INT25248 GNRH1 Regulation of CGA 4 1 0.30 1.22 0.62
101 INT25957 Gabrg1 Regulation of Localization of AVP 1 1 0.01 0 0.62
102 INT27067 Crh Positive_regulation of Localization of Avp 3 1 0.18 0.46 0.61
103 INT28845 su Negative_regulation of Positive_regulation of Scn2a1 1 1 0.27 1.27 0.61
104 INT26997 SST Positive_regulation of Negative_regulation of Gnrhr 1 1 0.00 0.08 0.59
105 INT26648 Binding of CEL and HP 1 1 0.04 0 0.58
106 INT25156 TRH Regulation of PRL 2 1 0.27 0.81 0.56
107 INT27871 Binding of FCGR1B and HSPD1 1 1 0.01 1.93 0.56
108 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 1 0.01 1.93 0.56
109 INT28119 Atm Negative_regulation of Cck 1 1 0.42 0 0.56
110 INT28925 Cpe Regulation of Sh2b3 1 1 0.04 0.14 0.55
111 INT25414 Positive_regulation of Drd2 Positive_regulation of Penk 1 1 0.38 0 0.53
112 INT24869 GAL Regulation of Localization of Gh 1 5 0.19 0.4 0.51
113 INT27730 Binding of ALB and Shbg 2 1 0.01 0.44 0.5
114 INT25524 Oprd1 Regulation of Localization of GCG 1 1 0.01 0.52 0.48
115 INT27066 Crh Positive_regulation of Localization of Oxt 1 1 0.40 0 0.48
116 INT28032 TNIP3 Negative_regulation of Acot1 1 1 0.00 0 0.47
117 INT26338 Binding of OPRM1 and Prl 1 1 0.02 0.37 0.47
118 INT26009 Cck Negative_regulation of Positive_regulation of Cckbr 1 1 0.26 0 0.47
119 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 1 0.06 0 0.46
120 INT27064 Kndc1 Positive_regulation of Localization of Oxt 1 1 0.00 0 0.46
121 INT28619 Negative_regulation of Penk Regulation of Crh 1 1 0.41 0 0.46
122 INT28081 POMC Regulation of Gene_expression of VIM 1 1 0.13 0.09 0.46
123 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 1 0.00 0 0.46
124 INT28863 Mtr Negative_regulation of Dhfr 1 1 0.04 0.87 0.45
125 INT28082 POMC Regulation of PDYN 1 1 0.04 0.09 0.45
126 INT25992 Pla2g5 Positive_regulation of Vip 1 1 0.49 0 0.45
127 INT28864 Mtx1 Negative_regulation of Dhfr 1 1 0.19 0.87 0.44
128 INT27997 Oprd1 Positive_regulation of Localization of Me1 1 1 0.03 0 0.44
129 INT25430 Gtf3a Regulation of Nppa 1 1 0.24 0.57 0.43
130 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 1 0.25 0 0.42
131 INT25618 Pomc Regulation of Gene_expression of Il1f5 1 2 0.17 0 0.42
132 INT25616 Pomc Regulation of Gene_expression of Il1 1 2 0.60 0 0.42
133 INT25157 TRH Regulation of TRH Regulation of PRL 1 1 0.29 0 0.42
134 INT27451 OPRM1 Positive_regulation of Localization of Lhb 1 1 0.01 0.1 0.41
135 INT26077 Binding of S1pr5 and St8sia2 1 2 0.00 0.14 0.39
136 INT28237 BBS2 Positive_regulation of Localization of Cck 1 1 0.04 0.33 0.39
137 INT24755 GAL Regulation of Regulation of Calca 1 1 0.16 0 0.38
138 INT27036 HERPUD1 Positive_regulation of Gene_expression of IL2 1 1 0.31 0 0.37
139 INT25763 Crh Positive_regulation of Prkacb 1 1 0.56 0.07 0.37
140 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 1 0.03 0.07 0.36
141 INT27032 ASNA1 Regulation of Gene_expression of IL2 1 1 0.03 0 0.36
142 INT26197 Qrfp Regulation of Localization of Crh 1 1 0.02 0 0.36
143 INT26168 Car2 Positive_regulation of Hrasls 1 1 0.10 0 0.36
144 INT28327 Binding of Sigmar1 and Abat 1 1 0.15 0.14 0.35
145 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 1 0.00 0.39 0.34
146 INT27029 HERPUD1 Regulation of Gene_expression of CD8A 1 1 0.41 0 0.34
147 INT24530 Gal Negative_regulation of Localization of Ins1 1 2 0.16 0.18 0.34
148 INT27033 HERPUD1 Regulation of Gene_expression of CD2 1 1 0.34 0 0.34
149 INT27848 Calca Positive_regulation of Localization of Ren 1 1 0.39 0.06 0.34
150 INT27030 HERPUD1 Regulation of CD4 1 1 0.41 0 0.34
151 INT27031 HERPUD1 Regulation of CD2 1 1 0.34 0 0.34
152 INT27035 HERPUD1 Regulation of CD8A 1 1 0.18 0 0.34
153 INT25526 Dst Regulation of Gh 1 1 0.00 0.26 0.34
154 INT27037 HERPUD1 Regulation of Gene_expression of CD4 1 1 0.55 0 0.34
155 INT27099 Vip Positive_regulation of Localization of Gnrhr 1 1 0.01 0.36 0.33
156 INT26193 OPRD1 Positive_regulation of MET 1 1 0.47 0 0.33
157 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 1 0.01 0.37 0.33
158 INT26196 Npy Positive_regulation of Localization of Crh 1 1 0.40 0 0.33
159 INT28005 NPC1 Negative_regulation of Rps6ka1 1 1 0.01 0.45 0.32
160 INT26071 Adarb1 Regulation of Localization of Crh 1 1 0.01 0.21 0.32
161 INT28688 Binding of Kng1 and Ctsl1 1 2 0.15 0 0.31
162 INT25614 Pomc Regulation of Localization of Il1f5 1 1 0.07 0 0.31
163 INT26235 Binding of GSR and Htr1a 1 1 0.12 0.09 0.31
164 INT26065 GHRH Regulation of Regulation of GH1 1 1 0.11 0 0.3
165 INT26737 Alox5 Regulation of Localization of Ins1 1 1 0.06 0.09 0.3
166 INT26738 Ca2 Positive_regulation of Localization of Ins1 1 1 0.12 0.09 0.3
167 INT25028 GNRH1 Positive_regulation of CGA 1 1 0.03 0 0.29
168 INT25169 GHRH Positive_regulation of Localization of Gh 1 2 0.12 0 0.29
169 INT25025 Regulation of GNRH1 Positive_regulation of CGA 1 1 0.03 0 0.29
170 INT26175 POMC Positive_regulation of GCG 2 1 0.47 0.57 0.28
171 INT25375 Trh Regulation of Gh 1 1 0.04 1.01 0.28
172 INT26942 Adra2c Positive_regulation of Localization of Ins1 1 1 0.13 0 0.28
173 INT26669 Nanog Regulation of Binding of Tlyr1 and 1 1 0.02 0 0.28
174 INT26577 SCN5A Positive_regulation of co 1 1 0.00 0 0.27
175 INT25946 Regulation of Binding of Penk and App 1 1 0.18 0.19 0.27
176 INT25944 Binding of Penk and App 1 1 0.15 0.19 0.27
177 INT25015 Binding of Spic and Vip 1 2 0.02 0.19 0.26
178 INT24529 Gal Regulation of Localization of Ins1 1 1 0.23 0.1 0.25
179 INT25247 TRH Regulation of CGA 1 1 0.26 0 0.24
180 INT25907 Binding of PRLR and Cish 1 1 0.00 0 0.23
181 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 1 0.00 0 0.22
182 INT26186 Binding of GREM1 and Cyth2 1 1 0.00 0 0.22
183 INT25720 Npy Negative_regulation of Avp 1 1 0.48 0.1 0.21
184 INT25721 Negative_regulation of Npy Negative_regulation of Avp 1 1 0.48 0.1 0.21
185 INT25617 Pomc Positive_regulation of Gene_expression of Il1 1 1 0.45 0 0.2
186 INT25615 Pomc Positive_regulation of Binding of Il1 and 1 1 0.49 0 0.2
187 INT27675 Plg Positive_regulation of Protein_catabolism of F13A1 1 1 0.00 0.75 0.2
188 INT25089 Glul Positive_regulation of Npr1 1 2 0.00 0 0.2
189 INT25951 Ins1 Regulation of Avp 1 2 0.16 0.15 0.19
190 INT28562 SOD1 Negative_regulation of Pacs1 1 2 0.03 2.63 0.19
191 INT28432 ADRA1D Positive_regulation of MPG 1 1 0.54 0.2 0.19
192 INT25495 AVP Positive_regulation of CRH 1 2 0.14 0 0.19
193 INT25053 Crh Regulation of PLOD1 1 1 0.11 0 0.19
194 INT25052 Crh Regulation of FSHR 1 1 0.08 0 0.19
195 INT26158 Binding of DBI and POMC 1 1 0.35 0.16 0.19
196 INT25497 AVP Positive_regulation of Localization of CRH 1 2 0.14 0 0.19
197 INT26089 S1pr5 Negative_regulation of Binding of S1pr5 and St8sia2 1 1 0.00 0.07 0.19
198 INT24759 Sct Positive_regulation of Gene_expression of Gast 1 1 0.08 0.63 0.18
199 INT25258 Fos Regulation of PENK 1 1 0.12 0.09 0.18
200 INT28722 Binding of T2 and Hdac11 1 2 0.11 0.14 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported in 1989. They are ordered first by their pain relevance and then by number of times they were reported in 1989. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in 1989 Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 1 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 48 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 51 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 106 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
6 INT1912 Gene_expression of Calca 18 1152 0.78 453.25 739.84
7 INT3439 Localization of Abat 44 1017 0.78 112.39 727.06
8 INT292 Localization of Penk 57 876 0.81 88.44 669.14
9 INT728 Positive_regulation of Penk 47 1068 0.70 186.9 636.87
10 INT2543 Positive_regulation of Calca 17 787 0.70 331.13 592.08
11 INT797 Regulation of Penk 27 812 0.62 111.13 542.24
12 INT5228 Positive_regulation of Fos 8 934 0.70 209.8 503.87
13 INT155 Positive_regulation of Prl 59 1233 0.70 317.93 457.82
14 INT1045 Localization of LH 42 1211 0.81 87.04 456.25
15 INT443 Localization of POMC 38 1020 0.81 284.52 443.17
16 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
17 INT4758 Positive_regulation of Localization of Calca 6 557 0.70 138.55 411.04
18 INT5895 Gene_expression of Oprm1 2 525 0.78 120.67 407.29
19 INT467 Gene_expression of POMC 29 1048 0.78 332.8 394.16
20 INT1395 Negative_regulation of Penk 24 537 0.59 87.33 389.81
21 INT2540 Negative_regulation of Calca 5 538 0.59 172.11 384.38
22 INT6580 Negative_regulation of Ptgs1 27 929 0.59 381.53 376.26
23 INT157 Positive_regulation of Localization of Prl 38 790 0.70 104.54 374.78
24 INT287 Localization of Cck 29 518 0.81 86.84 364.04
25 INT439 Localization of Gnrh1 38 976 0.81 100.96 363.25
26 INT720 Positive_regulation of POMC 38 807 0.70 237.37 353.83
27 INT5660 Binding of Oprd1 7 477 0.48 71.86 342.06
28 INT876 Localization of Gh1 28 843 0.80 67.75 340.82
29 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
30 INT2649 Regulation of Calca 32 433 0.62 146.05 330.95
31 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
32 INT162 Regulation of Prl 43 794 0.62 165.01 322.24
33 INT5979 Gene_expression of Oprd1 7 428 0.78 75.64 320.32
34 INT5540 Positive_regulation of Oprm1 2 344 0.70 76.77 319.71
35 INT4941 Positive_regulation of Oprd1 6 345 0.70 74.26 304.41
36 INT9131 Positive_regulation of Prkcg 1 431 0.70 130.8 302.41
37 INT477 Localization of Avp 23 813 0.81 131.58 300.4
38 INT161 Regulation of Localization of Prl 34 615 0.62 65.37 298.66
39 INT1352 Localization of Acot1 24 728 0.80 73.01 296.01
40 INT886 Gene_expression of Pomc 24 676 0.78 129.87 295.98
41 INT5379 Gene_expression of Fos 4 656 0.78 255.5 292.54
42 INT3579 Localization of Oxt 16 555 0.81 43.35 292.44
43 INT2365 Positive_regulation of Cck 10 354 0.70 87.8 277.41
44 INT6852 Localization of TNF 3 883 0.81 705.95 270.84
45 INT1396 Binding of Penk 11 355 0.48 22.79 269.65
46 INT5972 Gene_expression of IL1B 11 948 0.78 510.91 263.97
47 INT1893 Localization of Gh 44 1041 0.79 340.23 256.58
48 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
49 INT3948 Regulation of Cck 18 291 0.62 58.07 255.88
50 INT5501 Regulation of Oprd1 10 283 0.62 55.1 249.9
51 INT1005 Localization of Sst 14 385 0.81 26.31 244.56
52 INT738 Regulation of POMC 36 459 0.62 111.19 243.74
53 INT1902 Gene_expression of Cck 21 348 0.78 70.33 241.92
54 INT1562 Localization of Crh 35 499 0.81 126.74 236.68
55 INT5597 Gene_expression of Pdyn 15 433 0.78 62.97 235.47
56 INT1665 Positive_regulation of Pag1 8 270 0.68 186.63 229.87
57 INT4759 Negative_regulation of Localization of Calca 5 294 0.59 82.62 226.45
58 INT9987 Gene_expression of Abat 2 296 0.78 95.46 226.34
59 INT6406 Binding of Oprm1 2 280 0.48 40.54 226.26
60 INT1212 Binding of Oprl1 12 312 0.48 28.6 225.15
61 INT626 Localization of CALCA 8 289 0.81 125.39 221.15
62 INT1308 Localization of Pomc 14 457 0.81 66.83 217.5
63 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
64 INT767 Localization of Gnrhr 28 565 0.80 106.68 214.57
65 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
66 INT2651 Positive_regulation of Pomc 15 403 0.70 95.72 206.24
67 INT2391 Negative_regulation of PTGS1 4 501 0.59 207.62 205.6
68 INT798 Positive_regulation of Gene_expression of Penk 9 394 0.70 78.53 203.07
69 INT2211 Negative_regulation of Abat 7 267 0.59 66.51 200.98
70 INT156 Negative_regulation of Prl 37 542 0.59 131.97 192.24
71 INT528 Gene_expression of Prl 27 693 0.78 217.18 192.2
72 INT2085 Positive_regulation of LH 28 441 0.70 60.15 191.02
73 INT6354 Localization of Gabrg1 6 321 0.74 41.41 186.74
74 INT1652 Regulation of Pomc 10 387 0.62 61.01 186.51
75 INT24326 Gene_expression of Ngf 1 346 0.78 218.67 184.71
76 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
77 INT4803 Transcription of Penk 27 435 0.72 59.09 182.4
78 INT3440 Negative_regulation of Localization of Abat 13 221 0.57 33.94 180.36
79 INT12602 Negative_regulation of Oprm1 2 190 0.59 36.11 177.85
80 INT1429 Gene_expression of PDYN 9 308 0.78 61.33 175.65
81 INT19472 Gene_expression of Il1 8 554 0.76 419.75 175.35
82 INT943 Negative_regulation of Cck 9 205 0.59 38.42 174.78
83 INT26472 Regulation of Oprm1 3 191 0.62 35.84 173.1
84 INT5930 Positive_regulation of Oprm1 3 221 0.70 31.19 172.93
85 INT159 Negative_regulation of Localization of Prl 19 416 0.59 55.34 171.8
86 INT4937 Negative_regulation of Oprd1 8 224 0.59 44.51 171.11
87 INT438 Gene_expression of Crh 6 376 0.78 159.11 169.17
88 INT867 Gene_expression of IFNA1 1 930 0.78 594.85 168.03
89 INT739 Negative_regulation of POMC 15 358 0.59 102.28 166.77
90 INT1114 Localization of Ins1 37 748 0.80 192.95 165.48
91 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
92 INT2366 Binding of Cck 8 192 0.48 30.64 163.46
93 INT5127 Localization of Lhb 27 488 0.80 50.48 162.66
94 INT3448 Positive_regulation of Gh 22 521 0.69 180.03 161.18
95 INT5513 Negative_regulation of Pomc 11 295 0.59 60.9 158.63
96 INT21185 Binding of Ptprg 1 213 0.47 13.49 157.75
97 INT768 Positive_regulation of Oprl1 2 179 0.70 40.05 156.93
98 INT1303 Negative_regulation of Npr1 22 278 0.55 35.1 156.78
99 INT2640 Gene_expression of Pomc 18 424 0.78 120.72 155.37
100 INT6042 Binding of Oprm1 4 248 0.48 31.77 154.34
101 INT4740 Gene_expression of Th 10 298 0.78 61.27 154.03
102 INT2910 Regulation of Abat 2 169 0.62 36.95 153.53
103 INT1044 Negative_regulation of Localization of LH 8 358 0.59 25.95 151.31
104 INT4829 Positive_regulation of Localization of Abat 4 199 0.55 20.91 150.48
105 INT880 Positive_regulation of Localization of Gh1 11 304 0.70 14.79 150.23
106 INT5050 Regulation of Localization of Calca 3 149 0.62 41.25 148.57
107 INT6108 Gene_expression of Npy 4 292 0.78 110.65 148.21
108 INT13353 Positive_regulation of Tnf 1 332 0.70 248.75 148.1
109 INT2451 Positive_regulation of Avp 18 355 0.70 102.66 147.69
110 INT1033 Positive_regulation of Ca2 2 507 0.68 131.76 147.64
111 INT9852 Positive_regulation of Gpt 5 563 0.70 364.64 146.82
112 INT5116 Gene_expression of IL2 15 670 0.78 291.13 146.69
113 INT812 Localization of INS 23 1026 0.81 515.6 145.31
114 INT425 Localization of PRL 15 455 0.81 189.64 144.8
115 INT2379 Positive_regulation of Localization of LH 13 349 0.70 27.86 144.53
116 INT2780 Regulation of Gene_expression of Penk 4 265 0.62 32.45 143.88
117 INT1414 Regulation of Oprl1 12 169 0.62 32.05 139.99
118 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
119 INT1273 Gene_expression of Avp 15 356 0.78 90.56 138.7
120 INT2867 Gene_expression of CALCA 13 247 0.78 78.78 138.47
121 INT5061 Negative_regulation of Mme 15 306 0.59 51.97 136.9
122 INT4658 Binding of OPRM1 1 188 0.48 25.96 136.24
123 INT1047 Negative_regulation of LH 18 314 0.59 53.71 135.89
124 INT2541 Binding of Calca 10 200 0.48 67.14 134.62
125 INT5497 Positive_regulation of Crh 7 299 0.70 125.54 131.14
126 INT5380 Positive_regulation of Gene_expression of Fos 2 243 0.70 105.65 131.05
127 INT5595 Positive_regulation of Pdyn 11 223 0.70 48.37 130.14
128 INT1614 Gene_expression of Oprl1 2 164 0.78 31.43 127.74
129 INT5842 Gene_expression of Gfap 3 372 0.78 153.71 127.71
130 INT1878 Binding of HLA-B 6 440 0.48 321.16 127.36
131 INT695 Binding of POMC 15 304 0.48 56.66 126.85
132 INT5931 Regulation of Oprm1 1 149 0.62 18.15 125.93
133 INT6822 Gene_expression of Pdyn 9 215 0.78 35.99 125.76
134 INT416 Regulation of LH 17 253 0.62 31.48 125.55
135 INT6323 Positive_regulation of Gabrg1 6 213 0.70 45.08 124.34
136 INT4824 Positive_regulation of Tacr1 2 169 0.70 66.1 123.46
137 INT4259 Positive_regulation of Npr1 21 262 0.70 49.37 123.11
138 INT2106 Regulation of Localization of LH 11 279 0.62 22.37 122.77
139 INT252 Localization of GH1 19 529 0.80 227.4 122.05
140 INT6128 Positive_regulation of Localization of POMC 9 256 0.70 68.77 121.64
141 INT218 Positive_regulation of Th 3 245 0.70 40.5 120.1
142 INT2555 Positive_regulation of Localization of Penk 8 116 0.70 24.35 119.73
143 INT1026 Binding of Lbp 1 207 0.48 150.96 119.16
144 INT12501 Positive_regulation of Adarb1 5 166 0.58 36.94 118.92
145 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
146 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
147 INT7395 Localization of GNRH1 17 399 0.81 62.88 117.68
148 INT1438 Localization of Pomc 17 360 0.81 101.26 116.47
149 INT4207 Regulation of Avp 15 267 0.62 63.72 115.33
150 INT1793 Localization of CGA 18 379 0.81 67.38 114.69
151 INT90 Localization of Gast 12 400 0.81 137.67 113
152 INT1530 Regulation of Gh 24 382 0.61 115.96 112.47
153 INT7362 Gene_expression of Sst 4 185 0.78 41.73 111.37
154 INT7327 Regulation of Th 7 164 0.62 29.67 110.14
155 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
156 INT5283 Positive_regulation of Npy 3 191 0.70 66.77 109.2
157 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
158 INT8413 Gene_expression of Ptgs1 9 248 0.78 110.17 108.58
159 INT4936 Localization of Tacr1 5 125 0.80 35.7 107.7
160 INT3038 Gene_expression of INS 6 1583 0.78 1174.16 107.01
161 INT9012 Localization of Vip 18 283 0.81 31.71 106.16
162 INT12569 Localization of Oprd1 3 94 0.81 23.81 104.56
163 INT915 Positive_regulation of PRL 9 342 0.70 141.96 104.31
164 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
165 INT114 Binding of Oprl1 9 139 0.48 23 103.35
166 INT4742 Gene_expression of Tac1 1 177 0.78 69.99 102.66
167 INT1898 Regulation of Crh 9 220 0.62 61.33 102.64
168 INT5906 Negative_regulation of Oprm1 1 125 0.59 19.58 101.57
169 INT5940 Negative_regulation of Avp 19 236 0.59 67.86 101.2
170 INT397 Localization of SST 1 232 0.81 58.05 101.19
171 INT11381 Positive_regulation of IL1B 3 330 0.70 209.31 100.9
172 INT2159 Regulation of Localization of Gnrh1 11 200 0.62 13.28 99.07
173 INT1351 Gene_expression of Pag1 2 131 0.57 89.48 98.76
174 INT293 Protein_catabolism of Penk 3 161 1.00 11.71 98.45
175 INT7944 Positive_regulation of Fos 1 193 0.70 60.69 98.31
176 INT874 Positive_regulation of Gh1 2 244 0.70 27.17 97.98
177 INT4860 Positive_regulation of CALCA 1 148 0.00 73.35 97.61
178 INT4822 Localization of Ca2 4 417 0.80 99.57 96.45
179 INT940 Negative_regulation of Ptgs1 3 219 0.59 104.34 95.97
180 INT1004 Regulation of Sst 2 140 0.62 18.52 94.84
181 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
182 INT2862 Positive_regulation of Localization of Cck 2 108 0.70 20.75 94.25
183 INT11587 Gene_expression of CSF2 19 645 0.78 544.38 93.89
184 INT5865 Positive_regulation of Localization of Gh 18 282 0.69 84.86 93.5
185 INT203 Positive_regulation of Pomc 11 257 0.70 90.56 92.84
186 INT2122 Negative_regulation of Localization of Gnrh1 9 226 0.59 26.92 92.04
187 INT1281 Negative_regulation of Maoa 5 203 0.59 22.47 91.66
188 INT214 Localization of AVP 13 370 0.81 208.51 91.09
189 INT9516 Negative_regulation of Gabrg1 2 149 0.53 27.83 91.02
190 INT6437 Binding of YY1 5 154 0.47 26.3 90.46
191 INT1639 Negative_regulation of OPRM1 4 107 0.59 13.86 90.37
192 INT6585 Positive_regulation of Insrr 3 110 0.52 40.67 89.9
193 INT6214 Negative_regulation of Adarb1 9 123 0.50 26.39 89.57
194 INT1635 Gene_expression of Vip 5 245 0.78 53.36 88.13
195 INT7885 Positive_regulation of Localization of Oxt 7 160 0.70 14.36 87.7
196 INT3441 Regulation of Localization of Abat 6 117 0.38 8.67 87.59
197 INT5594 Regulation of Pdyn 11 137 0.62 27.04 86.63
198 INT1472 Positive_regulation of Ins1 2 349 0.69 146.2 86.36
199 INT5610 Positive_regulation of Insr 1 140 0.69 37.26 86.24
200 INT4798 Gene_expression of Nts 9 169 0.77 29.56 86.04
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